ImetelChat

Absolutely. This is total mismanagement. Any other competent leader would sail this gem like a charm. Despite all these breakthrough science and drug, the company has been run lame.

EMA decision by first half has been their maintained stance. I do recall them stating that sometime. What is not clear is that, why the sentiment turned this negative with the flat sales? More importantly, how did the fund managers knew this well in advance. Management!

Is this the trigger for selloff today? This has been one mystery investment for life. 12 years into, other than the optimism on science that many of use share here, the investment aspect has been beyond terrible. I wonder if the management even cares.

Despite the optimism that many of us have painfully shared and hoped for, the way this company and its valuation are managed seems to follow a different script. When it comes to communication or addressing the interests of retail investors, Geron management is, at best, far from exemplary.

Wow, 6 of them. Time to parse the details. We are in for good times ahead!

I see these two. Do you see more?

[ 1 ]
Initial Results from the QTc Substudy of the IMerge Phase 3 Trial Demonstrate Clinically Meaningful Efficacy, Manageable Safety, and Absence of Proarrhythmic Risk in Patients with Lower-Risk Myelodysplastic Syndromes Who Received Prior Therapies Beyond ...

In the June slide (slide 16) had a text stating that, J-code submission process initiated. So likely the approval came sometime this quarter?

https://s201.q4cdn.com/710325604/files/ ... -FINAL.pdf

Imetelstat's further query: (ChatGPT)

Imetelstat is directly related to the discussion of telomere length and telomerase expression as prognostic factors in cancers like lymphoma. Here’s how imetelstat comes into play:

1. Imetelstat’s Mechanism of Action:
Telomerase Inhibition:
Imetelstat is a ...

Here is what ChatGPT says:


Telomere length and telomerase expression have been studied extensively as potential biomarkers for prognosis in various cancers, including B-cell and T-cell lymphomas. Here’s an overview of how telomere length and telomerase activity can serve as predictors of survival ...

Not quite the same topic, but I found this comparison as per ChatGPT interesting: (Verbatim)


2. Indications:
Luspatercept (Reblozyl):
Approved for the treatment of anemia in adults with beta-thalassemia and MDS who require regular red blood cell transfusions.
Imetelstat (Raytelo):
Approved by the ...

I think. it is just about now. 6PM CEST.
https://congress-apps.ehaweb.org/eha2024/en-GB/pag/session/96161

OVERALL SURVIVAL, CLINICAL BENEFIT, AND DURABLE TRANSFUSION INDEPENDENCE WITH IMETELSTAT IN THE IMERGE PHASE 3 TRIAL OF RED BLOOD CELL-TRANSFUSION DEPENDENT LOWER-RISK MYELODYSPLASTIC ...

Wow! This has brought some serious nostalgia and I can't resist from writing a few words. I do recall the Turtle islands (and several such) discussions 10 years ago (Even Irishtrader was participating back then I guess). Since fishermangents's unfortunate passing, kinda lost interest. I had been a ...