Doth the plot thicken even further?

Forum rules
- Comments must be civil and on topic
- Back up claims with evidence/reasoning/sources (posting links is allowed)
- No commercials/harassment/spam
Post Reply
biopearl123
Posts: 2591
Joined: Fri Jul 20, 2018 5:13 pm

Doth the plot thicken even further?

Post by biopearl123 »

Date of patent August 26,2025:

United States Patent
Gryaznov et al.
(54) GUANINE ANALOGS AS TELOMERASE
SUBSTRATES AND TELOMERE LENGTH
AFFECTORS
(71) Applicant: Geron Corporation, Foster City, CA
(US)
(72) Inventors: Sergei M. Gryaznov, San Mateo, CA
(US); Ronald A. Pruzan, P'alo Alto,
CA (US); Kristina Pongracz,
Oakland, CA (US)
(73) Assignee: Geron Corporation, Foster City, CA
(US)
(*) Notice: Subject to any disclaimer, the term of this
patent is extended or adjusted under

Sergei of course is at MAIA

I was taken to task by some when I suggested that at least some of MAIAs IP might still be intertwined with Geron
seedylemon
Posts: 14
Joined: Thu Jan 24, 2019 8:57 pm

Re: Doth the plot thicken even further?

Post by seedylemon »

This is great news, biopearl.
The rights to the patent are transferred to Geron, giving credit to Sergei as inventor. Looks like we're still best buds.
biopearl123
Posts: 2591
Joined: Fri Jul 20, 2018 5:13 pm

Re: Doth the plot thicken even further?

Post by biopearl123 »

Seedylemon, truth is I dont have the IP sophistication to understand the full significance, but i think its good!
biopearl123
Posts: 2591
Joined: Fri Jul 20, 2018 5:13 pm

Re: Doth the plot thicken even further?

Post by biopearl123 »

Maybe HI could weigh in.
biopearl123
Posts: 2591
Joined: Fri Jul 20, 2018 5:13 pm

Re: Doth the plot thicken even further?

Post by biopearl123 »

These agents apparently could be administered orally.
biopearl123
Posts: 2591
Joined: Fri Jul 20, 2018 5:13 pm

Re: Doth the plot thicken even further?

Post by biopearl123 »

6 thio DG is a guanine analog. It can be administered orally or by other routes. Could this and other variants be the oral agent Dr. Scarlett alluded to? Anyone with knowledge of patents invited to comment.
biopearl123
Posts: 2591
Joined: Fri Jul 20, 2018 5:13 pm

Re: Doth the plot thicken even further?

Post by biopearl123 »

Looks like Geron could buy MAIA for (and return Sergei to the fold?) for about 42M.
Post Reply