Search found 11 matches

by Bigfun
Mon Mar 24, 2025 4:11 pm
Forum: ImetelChat
Topic: I had a vision…
Replies: 5
Views: 22882

Re: I had a vision…

"What are they gonna say about him? What are they gonna say? He was a kind man? He was a wise man? He had plans? He had wisdom?"
by Bigfun
Fri Jun 07, 2024 4:54 am
Forum: ImetelChat
Topic: WE ARE APPROVED
Replies: 52
Views: 57473

Re: WE ARE APPROVED

Congratulations to all! I've been dumb enough to wait over 20 years for Geron to get somewhere like this. Lots of inducement grants and finally they induced the RYTELO baby.

Also of course very thankful that the patients will finally get access to this. I truly wish Fishermangents had a chance to ...
by Bigfun
Thu Apr 25, 2024 7:09 am
Forum: ImetelChat
Topic: Paul Walker - NEA Venture Capital, Geron Portfolio Manager
Replies: 2
Views: 4073

Re: Paul Walker - NEA Venture Capital, Geron Portfolio Manager

Thanks for the post kmall!

Interesting that a majority of the companies in the life sciences portfolio have been acquired...
https://www.nea.com/portfolio?category=life-sciences
by Bigfun
Sat Apr 06, 2024 6:14 pm
Forum: ImetelChat
Topic: need more activity here - quiet before the storm?
Replies: 3
Views: 3299

Re: need more activity here - quiet before the storm?

Thanks for those links rccola335! While we wait through the quiet bit I thought this may be of interest. Slightly off topic but you may find this news regarding an evolving brain tumor treatment inspiring. This part of the write up reminded me of some of the ADCOM discussion around mitigating AEs ...
by Bigfun
Wed Mar 27, 2024 8:16 pm
Forum: ImetelChat
Topic: Take me to your leader
Replies: 5
Views: 5486

Re: Take me to your leader

Thanks for the video link rccola3365!

I thought this was one of the better interviews JS has ever given. I think most on this board would find it well worth watching. Let's hope we all " ride into the sunset" soon as he mentioned. This is the full video here
https://www.biotechtv.com/post/geron ...
by Bigfun
Fri Mar 22, 2024 5:27 am
Forum: ImetelChat
Topic: Ferroptosis Article (NIH)
Replies: 5
Views: 4609

Re: Ferroptosis Article (NIH)

Hi Hoosier, thanks for your thoughts and setting up this thread. I was reading through the other article you posted and was really interested in the other diseases where ferroptosis may play a role. There is a lot to think about there. There are many terms that I will need to lookup just to try and ...
by Bigfun
Thu Mar 21, 2024 4:41 am
Forum: ImetelChat
Topic: Are they getting more positive results
Replies: 6
Views: 5300

Re: Are they getting more positive results

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8840702/#:~:text=Cellular%20ferroptosis%20may%20be%20induced,GSH%2C%20the%20cofactor%20of%20GPX4.

Hi Folks, I was digging around some more today regarding ferroptosis. This Australian study got me thinking about it again. What was really interesting was ...
by Bigfun
Mon Mar 18, 2024 3:29 am
Forum: ImetelChat
Topic: Quite Surprising that....
Replies: 10
Views: 13770

Re: Quite Surprising that....

Thanks LWS, yea that was my understanding as well. I just thought maybe there were some clues as to why some do better that maybe did not come to the forefront of the ADCOM meeting but that had maybe been discussed. I would think that having more information here would be a good marketing tool and ...
by Bigfun
Sun Mar 17, 2024 7:24 pm
Forum: ImetelChat
Topic: Quite Surprising that....
Replies: 10
Views: 13770

Re: Quite Surprising that....

Yea talk about throwing the baby out with the bath water with those no votes, especially after hearing first hand from patients and doctors who are specialists on the frontlines of this thing. The chair seemed very casual and chipper with his vote, not sure the other really justified his "no" very ...
by Bigfun
Thu Mar 14, 2024 8:47 pm
Forum: ImetelChat
Topic: Vote 12-2 in Favor
Replies: 15
Views: 19435

Re: Vote 12-2 in Favor

Phew! I could not watch all of it but seems to me that the less positive views expressed were because they were looking at the risk across the whole population of low-risk MDS. They were concerned about the risks to groups that would maybe not respond but still potentially be exposed to the side ...
by Bigfun
Tue Mar 12, 2024 4:38 am
Forum: ImetelChat
Topic: Additional comments to FDA
Replies: 10
Views: 21458

Re: Additional comments to FDA

Hi Folks,

Thanks to BP for giving me access a while back! I have followed this board for sometime and appreciate you all for keeping the discussions going.

Not sure if anyone has mentioned this but there is a waiver listed for the ODAC regarding a conflict of interest for a doctor who is involved ...