ImetelChat

Are the patients in the J@J study worse in their condition than the one used in the MAYO study?

Yes, they are either patients who responded to Jakafi and then stopped responding or failed to respond in the first place. In other words end stage disease with failure to respond to conventional therapy. They have about a seven month life expectancy. bp

biopearl wrote:Yes, they are either patients who responded to Jakafi and then stopped responding or failed to respond in the first place. In other words end stage disease with failure to respond to conventional therapy. They have about a seven month life expectancy. bp

Thanks, biopearl i guess i was misled on YMB by william i thought that they were a different subset of patients.

I can't speak with certainty as some of the Mayo patients may have overlapped in criterion with the J and J population. Nonetheless the J and J population is distinguished by the end of the line nature of the natural history of their disease and their difficult to treat status.