Are the abstracts posted?

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biopearl123
Posts: 1720
Joined: Fri Jul 20, 2018 5:13 pm

Are the abstracts posted?

Post by biopearl123 » Tue May 14, 2024 4:19 pm

If you find them please post a link

rccola335
Posts: 365
Joined: Sat Sep 28, 2019 10:00 pm

Re: Are the abstracts posted?

Post by rccola335 » Tue May 14, 2024 5:12 pm

They were supposed to be posted to 16:00 CEST which means they are posted - we do not have a press release from Geron which means they probably don’t have anything


kmall
Posts: 778
Joined: Thu Mar 21, 2019 3:57 pm

Re: Are the abstracts posted?

Post by kmall » Tue May 14, 2024 5:28 pm

Courtesy of Frogg on the Stocktwits board:

This one is embargoed until 6/14

https://library.ehaweb.org/eha/2024/eha ... imetelstat



*On another note - JNJ-75276617 gets an oral presentation in combo with VENETOCLAX AND AZACITIDINE IN RELAPSED/REFRACTORY ACUTE MYELOID LEUKEMIA

https://library.ehaweb.org/eha/2024/eha ... ed%3D18498

rccola335
Posts: 365
Joined: Sat Sep 28, 2019 10:00 pm

Re: Are the abstracts posted?

Post by rccola335 » Wed May 15, 2024 1:04 am

the embargo regarding overall survival - the summary says the overall survival is not worse than placebo - is that a vague statement due to the embargo - are they going to present that Imetelstat has increased overall survival? Surprised Geron did not give a press release. I can't see them making that presentation unless they are going to present increased overall survival and I can't see the EHA giving an oral to hear that OS is the same for imetelstat and the placebo .
June 14-16 will be the presentations (PDUFA on the 16th) - if imetelstat displays an increase in overall survival doesn't that warrant leap frogging to front line treatment?
this is odd to say the least

biopearl123
Posts: 1720
Joined: Fri Jul 20, 2018 5:13 pm

Re: Are the abstracts posted?

Post by biopearl123 » Wed May 15, 2024 2:21 am

Pretty nice abstract rating an oral presentation with updated data continuing to confirm dramatic rises in Hgb in responders and long durations of TI. I don’t think there is anything that will touch that. Interesting about the OS and the conclusion that at about two years the OS is similar in both groups. What looked interesting was that the K-M curves diverged early on with about a little less that 100% of responder patients still alive at 18 months and about 20-25% of non responders dead. Then the curves start to converge and at 2 years are about the same. bp

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