How does Imetelstat compare to antibiotics that inhibit telomerase?

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rinconj
Posts: 6
Joined: Tue Jul 24, 2018 5:05 pm

How does Imetelstat compare to antibiotics that inhibit telomerase?

Post by rinconj » Wed May 26, 2021 6:08 am

Just found some articles on using some antibiotics that inhibit telomerase to treat cancers:


1.https://www.nature.com/articles/s41467-021-23068-1
2.https://today.uic.edu/can-antibiotics-t ... infections
3.https://m.ebiotrade.com/newsf/2013-7/20 ... 328895.htm

I am wondering if Imetelstat holds any advantage over other telomerase inhibitors?

rinconj
Posts: 6
Joined: Tue Jul 24, 2018 5:05 pm

Re: How does Imetelstat compare to antibiotics that inhibit telomerase?

Post by rinconj » Wed May 26, 2021 6:16 am

Excerpted from the following book:” Antibiotics oflaxacin and levofloxacin inhibit the telomerase in cell extracts. Helenalin (a natural sesquiterpene lactone), polyunsaturated fatty acids with cis-double bond, also inhibit the telomerase [ 20 ]. However, some dietary polyphenols have been suggested as telomerase inhibitors [ 38 ].”

https://www.intechopen.com/books/enzyme ... 2038%20%5D.

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