There are various presentations about imetelstat and telomerase. The melanoma one is interesting (potential new indication?), because it is a very agressive and deadly disease. We absolutely have to monitor these presentations and get a hold of the abstracts as soon as they are released.
(Thanks Ligas, for pointing us to this!)
Session Category: Molecular and Cellular Biology / Genetics
Abstract Number: 2731
Presentation Title: Impact of hypomethylating agents on hTERT expression and synergistic effect in combination with imetelstat, a telomerase inhibitor, in AML cell lines
Presentation Time: Tuesday, Apr 19, 2016, 8:00 AM -12:00 PM
Location: Section 2
Poster Board Number: 19
Author Block: Joshua Rusbuldt, Jacqueline Bussolari, Aleksandra Rizo, Fei Huang. Janssen Research & Development, LLC, Spring House, PA
Link: http://www.abstractsonline.com/Plan/Vie ... 0fb1922267
Abstract Number: 2732
Presentation Title: Myelosuppression in patients treated with the telomerase inhibitor imetelstat is not mediated through activation of toll-like receptors
Presentation Time: Tuesday, Apr 19, 2016, 8:00 AM -12:00 PM
Location: Section 2
Poster Board Number: 20
Author Block: Gabriela M. Baerlocher1, Joshua Rusbuldt2, Fei Huang2, Jacqueline Bussolari2. 1Inselspital/University Hospital of Bern, CH-3010 Bern, Switzerland; 2Janssen Research & Development, LLC, Spring House, PA
Link: http://www.abstractsonline.com/Plan/Vie ... 0fb1922267
Abstract Number: 2714
Presentation Title: Inhibition of human telomerase by new purine analogs
Presentation Time: Tuesday, Apr 19, 2016, 8:00 AM -12:00 PM
Location: Section 2
Poster Board Number: 2
Author Block: Wilnelly M. Hernandez-Sanchez1, Diane Baus1, Anthony J. Berdis2, Derek J. Taylor1. 1Case Western Reserve University, Cleveland, OH; 2Cleveland State University, Cleveland, OH
Link: http://www.abstractsonline.com/Plan/Vie ... 0fb1922267
Abstract Number: 2730
Presentation Title: Association of TERT promoter mutations with telomerase expression in melanoma
Presentation Time: Tuesday, Apr 19, 2016, 8:00 AM -12:00 PM
Location: Section 2
Poster Board Number: 18
Author Block: Seungjae Lee1, Patricia Opresko2, Alberto Pappo1, John Kirkwood3, Armita Bahrami1. 1St. Jude Children's Research Hospital, Memphis, TN; 2University of Pittsburgh Cancer Institute, Pittsburgh, PA; 3University of Pittsburgh Medical Center, Pittsburgh, PA
Link: http://www.abstractsonline.com/Plan/Vie ... 0fb1922267
Abstract Number: 2741
Presentation Title: A novel branched DNA-based multiplex method for telomere analysis at the single-cell level by flow cytometry
Presentation Time: Tuesday, Apr 19, 2016, 8:00 AM -12:00 PM
Location: Section 2
Poster Board Number: 29
Author Block: Steve Lai, Leslie Sias, Castle Funatake. Affymetrix, Inc., Santa Clara, CA
Link: http://www.abstractsonline.com/Plan/Vie ... 0fb1922267
AACR2016: imetelstat and telomerase on the agenda; melanoma as a new indication?
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Fishermangents
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Fishermangents
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Re: AACR2016: imetelstat and telomerase on the agenda; melanoma as a new indication?
Two observations:
- telomerase is becoming a regular topic on major conferences
- Janssen R&D steps up to the stage as co-author of the two imetelstat papers
- telomerase is becoming a regular topic on major conferences
- Janssen R&D steps up to the stage as co-author of the two imetelstat papers