Here's the link:
http://www.investor.jnj.com/pharmaceutical-pipeline
Search found 367 matches
- Tue Apr 17, 2018 3:37 pm
- Forum: ImetelChat
- Topic: J and J confirms continued Imetelstat development
- Replies: 2
- Views: 2975
- Tue Apr 17, 2018 3:34 pm
- Forum: ImetelChat
- Topic: J and J confirms continued Imetelstat development
- Replies: 2
- Views: 2975
J and J confirms continued Imetelstat development
Imetelstat remains on list for NME filing. Will post link. bp
- Sun Apr 15, 2018 6:02 am
- Forum: ImetelChat
- Topic: (08-02-2018) - Janssen BioTech applies for global patent for combo treatment for hematologic cancers, incl imetelstat
- Replies: 5
- Views: 11479
Re: (08-02-2018) - Janssen BioTech applies for global patent for combo treatment for hematologic cancers, incl imetelsta
Dogone, not to worry, you have not inhaled too much leaked gas. Yes the idea is that conventional chemo kills many cells but some cells appear to be chemo resistant with different CD markers and are considered CSCs (cancer stem cells) as they lead the recurrences back with a vengeance. These cells m...
- Thu Apr 12, 2018 3:17 am
- Forum: ImetelChat
- Topic: From the FDA re Breakthrough and AA
- Replies: 0
- Views: 2842
- Sat Apr 07, 2018 8:54 pm
- Forum: ImetelChat
- Topic: Important upcoming dates to watch
- Replies: 0
- Views: 2881
Important upcoming dates to watch
1. April 17th J and J first quarter release, if Imetelstat is still on list that would be a good thing (that would be an understatement) 2. April 25th ASCO program/abstract release--maybe some insight as to ongoing studies (unlikely) or a glimpse into early preclinical combination studies/AML (more ...
- Mon Apr 02, 2018 3:03 am
- Forum: ImetelChat
- Topic: Welcome to Q2
- Replies: 0
- Views: 2806
Welcome to Q2
Hello and best wishes for a Happy Passover/Easter season to all. We are now entering Q2. The importance of this quarter and the next need no emphasis but I will summarize what we know will and what I think might happen. We know that the next internal review will occur "before the end" of this quarte...
- Sat Mar 31, 2018 4:38 am
- Forum: ImetelChat
- Topic: Repost from SA by biopearl re recent events
- Replies: 2
- Views: 4474
Re: Repost from SA by biopearl re recent events
Hi jpheis, 1. John’s dose was 7.5. He was not allowed to increase his dose. If I remember correctly it was related to the FDA hold which basically paralyzed Dr. Teferri’s study. John’s amazing wife tried valiantly to get some flexibility in how his treatment was approached but was not successful eit...
- Thu Mar 29, 2018 4:49 am
- Forum: ImetelChat
- Topic: Repost from SA by biopearl re recent events
- Replies: 2
- Views: 4474
Repost from SA by biopearl re recent events
I just put down some thoughts that is a summary of some of the important discussion points that have been raised and examined by multiple posters on SA: First of all I want to start this post by thanking CKTC, HI, AW, Sdraw and especially MTB for helping me have this cathexis (not catharsis). I real...
- Tue Mar 27, 2018 5:05 pm
- Forum: ImetelChat
- Topic: Another nice summary from Sdraw
- Replies: 0
- Views: 2964
Another nice summary from Sdraw
Repost from YMB, Sdraw: sdrawkcabeman12 minutes ago Here’s a micro-brief on some of the publications: From the Huff, et al, paper on MM: “Over the course of treatment, the frequency of MM CSCs decreased significantly, on average 2 fold every 30 days.” 100% hematologic response in ET, with 89% CR, dr...
- Mon Mar 26, 2018 10:45 pm
- Forum: ImetelChat
- Topic: Link to recent article on pancreatic cancer cell lines
- Replies: 2
- Views: 4824
Link to recent article on pancreatic cancer cell lines
Repost from whyted/Sdraw: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663552/
- Sun Mar 25, 2018 8:49 pm
- Forum: ImetelChat
- Topic: Just saw a reference to a 2017 article in Blood
- Replies: 2
- Views: 2737
Re: Just saw a reference to a 2017 article in Blood
Yes indeed. If Jak 2 inhibitors encourage clonal drift toward resistant mutations such as the dreaded ASXL-1 mutation then the effects of Imetelstat in the R/R group may be even more profoundly important. bp
- Sun Mar 25, 2018 8:46 pm
- Forum: ImetelChat
- Topic: Does anyone have any idea how transparent Janssen
- Replies: 1
- Views: 2151
Re: Does anyone have any idea how transparent Janssen
Dog--They absolutely do not have to divulge. Scarlett has alluded to an extensive about of preclinical research (also know as skunkworks) that is going on at Janssen we know nothing about. Why tip your hand to the competition? Lots of hints that have open the door to one's imagination, the Yale stud...
- Sat Mar 24, 2018 3:37 pm
- Forum: ImetelChat
- Topic: Continuation of excellent posts by Sdraw on YMB
- Replies: 5
- Views: 6987
Re: Continuation of excellent posts by Sdraw on YMB
jpheis, Great Idea (I just have to learn how--will consult with Fish) bp
- Fri Mar 23, 2018 9:20 pm
- Forum: ImetelChat
- Topic: Continuation of excellent posts by Sdraw on YMB
- Replies: 5
- Views: 6987
- Fri Mar 23, 2018 6:40 pm
- Forum: ImetelChat
- Topic: Continuation of excellent posts by Sdraw on YMB
- Replies: 5
- Views: 6987
Re: Continuation of excellent posts by Sdraw on YMB
Here is a link to the rest of Sdraw's recent posts. Very worthwhile reading. bp
- Fri Mar 23, 2018 5:54 pm
- Forum: ImetelChat
- Topic: Continuation of excellent posts by Sdraw on YMB
- Replies: 5
- Views: 6987
Continuation of excellent posts by Sdraw on YMB
Reposted from ymb, Sdraw deconstructs arguments made by presumed short : sdrawkcabeman23 minutes ago (1 of 4 posts) Whyted, thanks for commuting my post to Alpha Exposure(AE). Unfortunately, reading AE’s response, I see he still hasn’t grasped the absurdity of what he wrote. He said, “You seem to ag...
- Fri Mar 23, 2018 1:47 pm
- Forum: ImetelChat
- Topic: Response to Sargasso (thanks for the great articles)
- Replies: 1
- Views: 4025
Response to Sargasso (thanks for the great articles)
After reading and thinking about the articles kindly provided by sargasso, even the Harvard Law Review has something to say about market manipulation by short sellers and hedge funds. In this age of big data, bots and fake news the best defense is to be sure we stay well educated and can make decisi...
- Fri Mar 23, 2018 12:14 am
- Forum: ImetelChat
- Topic: Concerning anonymous short sellers
- Replies: 5
- Views: 7977
Re: Concerning anonymous short sellers
Sargasso, thank you for reposting this. I have found virtually all of Sdrawkcabeman's posts to be insightful and informed. Thank you also for sharing the articles that help in understanding the attempts of "shorts" in manipulating markets. We had an up day despite a significant down market. One woul...
- Wed Mar 21, 2018 9:27 pm
- Forum: ImetelChat
- Topic: In case Sdraw reads this board--repost from SA
- Replies: 3
- Views: 5238
In case Sdraw reads this board--repost from SA
Jay, I read every one of Sdraw's posts carefully and slowly. He has really helped me think about the data and structure of the various studies. I hope he reads this board because this question is for him (or anyone else who might be able to respond). I have always been sensitive to the ethics of how...
- Wed Mar 21, 2018 7:36 pm
- Forum: ImetelChat
- Topic: General Announcement--Assistant Moderator
- Replies: 1
- Views: 3604
General Announcement--Assistant Moderator
Fish has asked me to be assistant moderator on this board and I am honored to do so. We have been fortunate to take advantage of Fish's high quality compilation of pertinent articles, videos and links to various company presentations/meeting/posters/abstracts etc. We have been very fortunate to have...