Search found 250 matches
- Sat Dec 24, 2022 7:12 pm
- Forum: ImetelChat
- Topic: We have done our homework, now the hard part, patience
- Replies: 15
- Views: 4325
Re: We have done our homework, now the hard part, patience
Thanks all for your good thoughts and wishes! And kmall, all good thoughts and important reminders for caregivers. I am very sorry about your brother’s passing and I’m thankful for not having so much windshield time on top of taking care of my wife as with your father-in-law. I think the grieving pa...
- Thu Dec 22, 2022 6:26 am
- Forum: ImetelChat
- Topic: We have done our homework, now the hard part, patience
- Replies: 15
- Views: 4325
Re: We have done our homework, now the hard part, patience
Thanks to all for piling in here and for all recent posts on ImetelChat. And to stanleyock, thanks for your post and congratulations on maintaining your sanity and investment, a few here have not. I am grateful that we have such a great board to vent, sound off, unite, support, challenge, learn, etc...
- Tue Dec 20, 2022 11:51 pm
- Forum: ImetelChat
- Topic: We have done our homework, now the hard part, patience
- Replies: 15
- Views: 4325
We have done our homework, now the hard part, patience
The Imetelstat TI science has shown: 1. Net net: Strong safety and efficacy, clinical benefits correlated with decreased telomerase activity and depletion of malignant cells. 2. Benefits: Recovery of bone marrow, healthy blood production, survival increased, symptom relief Even so we are edgy, frust...
- Fri Dec 16, 2022 9:28 pm
- Forum: ImetelChat
- Topic: More Ash 2022 - check out at 6 min 25 sec
- Replies: 1
- Views: 619
- Sat Apr 23, 2022 10:50 pm
- Forum: ImetelChat
- Topic: Questions for the Shareholders meeting
- Replies: 7
- Views: 2877
Re: Questions for the Shareholders meeting
Many great thankyou’s again biopearl123 for all you do on and for this board regarding our understanding and use in our personal medical and investing lives! I’m not sure there are many legitimate additional questions to be added to your list but I will submit a couple that you can add or not. Just ...
- Sat Apr 09, 2022 10:38 pm
- Forum: ImetelChat
- Topic: There are many ways to think about partnering
- Replies: 177
- Views: 371418
Re: There are many ways to think about partnering
VIVO Capital steps up with an aggregate number of shares equaling a 5.9% position (22,857,143) in Geron. The aggregate per the Schedule 13G consists of 15,238,095 common stock shares and 7,619,048 shares of common stock shares issuable upon exercise of certain warrants. https://d18rn0p25nwr6d.cloudf...
- Tue Jan 11, 2022 6:28 am
- Forum: ImetelChat
- Topic: 2022 - a Monumental Year.........
- Replies: 3
- Views: 1947
Re: 2022 - a Monumental Year.........
Thanks again kmall for your efforts here! I think a bell you rang for me on this post along with your “A Purple Squirrel & Venetoclax Combo – AML & Lymphoid Market Potential” is that dots are being connected, late stage CTs are progressing and new ones, even combinations, are getting ready to start ...
- Tue Jan 11, 2022 6:26 am
- Forum: ImetelChat
- Topic: There are many ways to think about partnering
- Replies: 177
- Views: 371418
Re: There are many ways to think about partnering
While it may not always sound like it, I do believe partnerships have great value and are coming. However, put me in the “be cautious” column regarding partnering. I actually hope the Ex-US partnerships come sooner and are even more significant in value than we expect but I think it is helpful to un...
- Sat Jan 08, 2022 11:02 pm
- Forum: ImetelChat
- Topic: Time Flies Like An Arrow
- Replies: 9
- Views: 3260
Re: Time Flies Like An Arrow
Kmall and biopearl, thanks for the good thoughts and perspective as usual! Yes, there are times when a padded room is the only reprieve with some of the mystifying things occurring with the Imetelstat studies. With all the “bright minds and regulatory procedure alternatives” at the FDA, can anyone t...
- Sat Jan 08, 2022 10:30 pm
- Forum: ImetelChat
- Topic: Ashah’s search for p values
- Replies: 2
- Views: 1515
Re: Ashah’s search for p values
biopearl, thanks again for pushing the envelope here! I know you know this but the concepts and usage of p-value is not for the faint of heart! I have a BA in math with a fair amount of statistics included but given that education is now well over 50 years in the past, p-value is merely a faint remn...
- Sat Jan 08, 2022 9:19 pm
- Forum: ImetelChat
- Topic: There are many ways to think about partnering
- Replies: 177
- Views: 371418
Re: There are many ways to think about partnering
Thanks for the feedback bucbeard, always nice to hear from you! LWS I appreciated your various cuts at this thread’s thought process and your opinions on the way forward. I have, as most here, spent time on understanding what the JNJ/Geron partnership offered and what was missing. Much of what went ...
- Mon Dec 20, 2021 11:36 pm
- Forum: ImetelChat
- Topic: Time Flies Like An Arrow
- Replies: 9
- Views: 3260
Re: Time Flies Like An Arrow
Time flies like an arrow most of the time, but not always. When you are wasting away due to hematological cancer or the clock ticking for any cancer for that matter, time definitely tends to “fly like an arrow”. However, when one is in the dentist’s chair not so much. And certainly not when waiting ...
- Tue Dec 14, 2021 11:42 pm
- Forum: ImetelChat
- Topic: COVID-19 Has Contributed to Chronic Blood Shortage
- Replies: 0
- Views: 1769
COVID-19 Has Contributed to Chronic Blood Shortage
With all the things going on with these P3 studies I hope the blood supply issues doesn’t get lost in the shuffle! “The shortages affect many people, but perhaps cancer patients most of all. People with cancer need more blood transfusions than those with any other disease, and they use about a quart...
- Wed Dec 08, 2021 7:34 pm
- Forum: ImetelChat
- Topic: There are many ways to think about partnering
- Replies: 177
- Views: 371418
There are many ways to think about partnering
This from the Geron Website (About Us tab drop down under Partnering) Partnering Corporate Development Since our founding, Geron has focused on strong science and the pursuit of R&D excellence to discover and develop innovative, first-in-class therapies for the treatment of cancer as evidenced throu...
- Fri Nov 05, 2021 5:41 pm
- Forum: ImetelChat
- Topic: Hunt
- Replies: 10
- Views: 2724
Re: Hunt
biopearl123, as expected you have spent considerable time trying to discern where Geron could be going here and what questions we could ask to find the answers we are looking for on attacking these diseases, approval, investments, etc. I personally do not feel like we have enough pieces of the puzzl...
- Mon Oct 04, 2021 11:52 pm
- Forum: ImetelChat
- Topic: Dr John Mascarenhas – "I'm a believer"
- Replies: 0
- Views: 1665
Dr John Mascarenhas – "I'm a believer"
Found this interview on Patient Power educational and another glimpse of what we have in Imetelstat. Current Myelofibrosis Research, Clinical Trials, and Treatments (Published on July 6, 2021) https://patientpower.info/experts-share-primary-myelofibrosis-research-updates/?ap=590&utm_source=e-News+Su...
- Mon Oct 04, 2021 10:51 pm
- Forum: ImetelChat
- Topic: While we're waiting......you're hired !!! Pt 3
- Replies: 8
- Views: 2355
Re: While we're waiting......you're hired !!! Pt 3
Great investigative work kmall! I don’t think I have ever seen the likes of what you have compiled re: a company’s employees from an external view point. And I like the logic and analysis you have added with it. Just very good due diligence and efforts not typical for most of us who just look at the...
- Fri Oct 01, 2021 9:16 pm
- Forum: ImetelChat
- Topic: Sept 30 presentation
- Replies: 4
- Views: 1961
Re: Sept 30 presentation
Agreed, Dr. Scarlett is exuding excitement about Geron’s prospects, of course in his low key manner. And has dropped new hints and slants in each presentation to keep it interesting and continually pressing key points regarding the differentiation of Imetelstat’s TI characteristics to other drugs. I...
- Wed Sep 29, 2021 5:49 pm
- Forum: ImetelChat
- Topic: On the topic of blood transfusions
- Replies: 7
- Views: 2701
Re: On the topic of blood transfusions
I did mention in the "Btw" on my last post that the current math would change as Imetelstat 2.0 and combinations come into the market. I personally don’t see anything to rival the reductions in RBC transfusions, not now, not in 8-10 years, probably just naïve. But I think Imetelstat and Geron stand ...
- Mon Sep 27, 2021 11:06 pm
- Forum: ImetelChat
- Topic: On the topic of blood transfusions
- Replies: 7
- Views: 2701
Re: On the topic of blood transfusions
Okay thank you biopearl123, I didn’t do my homework very well and your estimates from the “Reality check” post from April-2020 continues to be in the ballpark. But I’m going to continue to beat the dead hope of sanity here. If I take from your link above, the 50% of LR MDS patients have a TB of 8/16...