Search found 529 matches

by Fishermangents
Sun Dec 20, 2015 6:17 pm
Forum: ImetelChat
Topic: JNJ: A Collaborative Touch (Motley Fool, 19 Dec 2015)
Replies: 0
Views: 1579

JNJ: A Collaborative Touch (Motley Fool, 19 Dec 2015)

A quote from the article 'Will JNJ raise its dividend in 2016?' by Sean Williams, Motley Fool 19 Dec 2015 A collaborative touch The last piece of the puzzle for J&J, and somewhat an extension of the pharmaceutical segment discussion above, is that it has been outstanding when it comes to forging col...
by Fishermangents
Sat Dec 19, 2015 11:42 am
Forum: ImetelChat
Topic: Yesterday volume 15 mln, AH 5 mln: what happened?
Replies: 3
Views: 2217

Re: Yesterday volume 15 mln, AH 5 mln: what happened?

From jwjmurphy (YMB, 19 Dec 2915) "Smart hedges covering. Hedged all along now they own the stock!!! No choice really. see one MM on both sides the trade with 10,000 bids/asks one penny apart! But today, often 2 whole big pennies apart, rare. Then covered at close and later cause the game is up. The...
by Fishermangents
Sat Dec 19, 2015 11:24 am
Forum: ImetelChat
Topic: Yesterday volume 15 mln, AH 5 mln: what happened?
Replies: 3
Views: 2217

Yesterday volume 15 mln, AH 5 mln: what happened?

Yesterday (Dec 18) the volume was almost 10x higher than average. AH only was 5 mln, yet without significant price movement. What happened? Who were sellers and who were buyers? How can shorts cover (if they did) without moving PPS up more significantly than it did based on such volumes? Any thoughts?
by Fishermangents
Sat Dec 19, 2015 11:19 am
Forum: ImetelChat
Topic: Time line comparison Imetelstat vs Daratumumab
Replies: 0
Views: 2063

Time line comparison Imetelstat vs Daratumumab

From sdrawkcabeman (YMB), 18 Dec 2015 Genmab announced a partnership with Janssen for exclusive worldwide development and manufacture of Daratumumab on Aug 30, 2012. Breakthrough therapy announced on May 1, 2013. Approval in Nov 2015, 3 years 3 months from the partnership announcement. Geron announc...
by Fishermangents
Thu Dec 17, 2015 5:33 pm
Forum: ImetelChat
Topic: MPN Research Updates From a Panel of Experts at ASH 2015
Replies: 0
Views: 1398

MPN Research Updates From a Panel of Experts at ASH 2015

Panel interview at YouTube with Ruben Mesa (Mayo Clinic Scottsdale) and Bart Scott (Fred Hutchinson Cancer Research Center) about progress in MPN research and treatment options. 15.22: Rubin Mesa mentions imetelstat 18.07: Bart Scott mentions imetelstat in the context of promising drugs that seem to...
by Fishermangents
Thu Dec 17, 2015 3:37 pm
Forum: ImetelChat
Topic: Continuation decission (JnJ) and opt-in rights (Geron)
Replies: 0
Views: 1521

Continuation decission (JnJ) and opt-in rights (Geron)

Under the terms of the Collaboration Agreement, Janssen is not obligated to make any additional payments to us until it makes an affirmative Continuation Decision following the results of the IMbarkTM Study, or, if the IMbarkTM Study is terminated early or suspended for an extended period of time, w...
by Fishermangents
Thu Dec 17, 2015 3:33 pm
Forum: ImetelChat
Topic: Milestone payments
Replies: 0
Views: 1619

Milestone payments

From the 10Q in August, just to have all the formal information. In the event that Janssen elects to continue to maintain its license rights and advance the development of imetelstat in any indication within the applicable timeframe set forth in the Collaboration Agreement (such election, the Contin...
by Fishermangents
Thu Dec 17, 2015 2:43 pm
Forum: ImetelChat
Topic: Telomeres Rule
Replies: 0
Views: 1373

Telomeres Rule

Interesting article about telomeres, telomerase, cancer and imetelstat. Some quotes: 'Telomerase balances the telomere shortening that occurs during cell division by adding telomere repeats onto chromosome ends. While the enzyme exists at very low or undetectable levels in normal somatic cells, it i...
by Fishermangents
Wed Dec 16, 2015 11:17 pm
Forum: ImetelChat
Topic: 'Good Spirits' from Irish
Replies: 1
Views: 1172

'Good Spirits' from Irish

from Yahoo MB:

'John back from Mayo again. Continues to do well. Everyone at Mayo in good spirits.'
by Fishermangents
Tue Dec 15, 2015 11:21 am
Forum: ImetelChat
Topic: Geron: Calcualting the Potential Value Gap
Replies: 3
Views: 1907

Re: Geron: Calcualting the Potential Value Gap

I_B_I, thanks for your reflections. From a business point of view the 25% higher prices for a 1 year of imetelstat treatment is nice, from a societal point of view we may run into some trouble... But that is, I believe, beyond our reach. However, pricing is a strategic choice. We have this phenomeno...
by Fishermangents
Tue Dec 15, 2015 10:55 am
Forum: ImetelChat
Topic: Hello Everyone!
Replies: 3
Views: 1819

Re: Hello Everyone!

Hi irish, great to have you here! I am so happy John is going well. He seems to be responding exceptionally well! Yahoo has become a strange place. Not because of all the speculation, but more because of the manipulation and constant bullying. Multiple id's have destroyed credibility. Let's make sur...
by Fishermangents
Mon Dec 14, 2015 8:45 pm
Forum: ImetelChat
Topic: What's next on the agenda?
Replies: 5
Views: 2172

Re: What's next on the agenda?

There are people who think that it will remain silent for months from now. Although we don't see any scheduled events, I am not so sure about that. JnJ and Geron are not sending out PR's on any occasion, while Dr.Scarlett seems not be over-promising. That doesn't mean that there are no dynamics unde...
by Fishermangents
Mon Dec 14, 2015 4:07 pm
Forum: ImetelChat
Topic: Geron: Calcualting the Potential Value Gap
Replies: 3
Views: 1907

Geron: Calcualting the Potential Value Gap

On 17 September we have seen the article on SA titling "Geron: Calcualting the Potential Value Gap". This was a nice attempt to provide rationale for a potential value gap and to quantify it. In the meanwhile we know more, so there may be some parameters which we now can fill into this calculation. ...
by Fishermangents
Mon Dec 14, 2015 3:54 pm
Forum: ImetelChat
Topic: Investing In Johnson & Johnson's Pharmaceutical Collaborations Can Provide Dramatic Returns
Replies: 1
Views: 2134

Re: Investing In Johnson & Johnson's Pharmaceutical Collaborations Can Provide Dramatic Returns

Here are some interesting comments by Phil from SA: "Very nice article that is logical and straightforward. I noted the same algorithm in my articles in GERN and felt that algo was a primary basis for JNJ's interest (and hence my interest) in the name. If you actually look at the algo and input numb...
by Fishermangents
Fri Dec 11, 2015 6:45 pm
Forum: ImetelChat
Topic: Investing In Johnson & Johnson's Pharmaceutical Collaborations Can Provide Dramatic Returns
Replies: 1
Views: 2134

Investing In Johnson & Johnson's Pharmaceutical Collaborations Can Provide Dramatic Returns

Some quotes from SA article: JNJ is now one of the world's fastest drug developers. Since 2009, JNJ has enjoyed the most FDA approvals of any company, launching 14 new drugs that generated cumulative sales of $18.7B through year-end 2014. The company expects an additional 10 new product filings by 2...
by Fishermangents
Fri Dec 11, 2015 3:34 pm
Forum: ImetelChat
Topic: What's next on the agenda?
Replies: 5
Views: 2172

Re: What's next on the agenda?

In Europe we have the EHA 2016 - The 21st European Hemathology Association Congress (Copenhagen, 9 - 12 June 2016). Would be good to make an overview of events up to July 2016.
by Fishermangents
Fri Dec 11, 2015 1:58 pm
Forum: ImetelChat
Topic: JNJ: anticipated imetelstat NME filing in 2017
Replies: 0
Views: 1879

JNJ: anticipated imetelstat NME filing in 2017

This presentation is dated 20 May 2015. But I just found the presentation to be so comprehensive and important that I made it available through https://imetelstat.eu/commercial. It is a PDF (19 MB, 254 slides!) which downloads directly when you click on it. If it doesn't open you should get it from ...
by Fishermangents
Fri Dec 11, 2015 11:21 am
Forum: ImetelChat
Topic: My take on Geron's strategy in the JnJ partnership
Replies: 1
Views: 1629

My take on Geron's strategy in the JnJ partnership

In a strategic partnership the complementary aspects of the cooperation are the basis of any successful partnership (one of the things I once learned at INSEAD...). In order to start a discussion I try give my views on how Geron may want to keep its cooperation with JnJ successfull and sustainable. ...
by Fishermangents
Thu Dec 10, 2015 3:43 pm
Forum: ImetelChat
Topic: Take aways from Oppenheimer
Replies: 6
Views: 3297

Re: Take aways from Oppenheimer

Phil: agree with your observation. Dr. Scarlett didn't become too frenzy about it, probably because formally TI is not primary end point. But he clearly stated that they will measure everything they could in order to indicate the depth and nature of the responses. Clearly TI is a major one, in fact ...
by Fishermangents
Thu Dec 10, 2015 9:23 am
Forum: ImetelChat
Topic: Welcome!
Replies: 0
Views: 1423

Welcome!

Dear all, thanks for joining this board. I highly value you as being members of the first hour! We'll try to keep this MB clean and honest. Hopefully it will become a place where people with various interests and backgrounds feel comfortable. There are some things that are important in making this p...