Search found 157 matches

by cheng_ho
Wed Sep 28, 2016 11:41 pm
Forum: ImetelChat
Topic: Sergei Gryaznov (Alios/JnJ) to present about imetelstat 28 September 2016
Replies: 9
Views: 5515

Re: Sergei Gryaznov (Alios/JnJ) to present about imetelstat 28 September 2016

Here's a tweet from the conference to prove Sergei was there... but according to pursang on Seeking Alpha, the meeting wasn't recorded or archived. They suggest that people can "contact Sergei directly if they have questions".

https://twitter.com/AnnemiekeAarts2/sta ... 29280?s=09
by cheng_ho
Wed Sep 28, 2016 10:08 pm
Forum: ImetelChat
Topic: Sergei Gryaznov: the interview
Replies: 2
Views: 2625

Re: Sergei Gryaznov: the interview

Let's be glad that computer companies don't work this slowly :mrgreen:
by cheng_ho
Wed Sep 28, 2016 10:07 pm
Forum: ImetelChat
Topic: Where can one with MF go to get in line for Imetelstat treatments?
Replies: 3
Views: 3771

Re: Where can one with MF go to get in line for Imetelstat treatments?

We passed a "right to try" law last year in NH. Last weekend the NH GOP added FDA nullification to the party platform.

The only way medicine can progress is if the terminally ill are allowed to try new treatments.
by cheng_ho
Mon Sep 19, 2016 7:06 pm
Forum: ImetelChat
Topic: For Cheng Ho
Replies: 8
Views: 4397

Re: For Cheng Ho

>the PRs/CRs observed by Mayo seemed to be exciting enough

I was directly quoting Tefferi, from his Italian talk. Take it up with him... if we can. Has anyone seen anything from his talk on Saturday? There's nothing on the MPN foundation site or their FB page...
by cheng_ho
Sun Sep 18, 2016 10:49 pm
Forum: ImetelChat
Topic: The MDS market
Replies: 7
Views: 3843

Re: The MDS market

Sargasso, I presume you're being sarcastic. But having no sense of humor, I'm going to point out that Fossel's recent book suggests that Alzheimer's is caused by glial cell aging and must be treated with telomerase activators, not inhibitors.
by cheng_ho
Sun Sep 18, 2016 10:44 pm
Forum: ImetelChat
Topic: For Cheng Ho
Replies: 8
Views: 4397

Re: For Cheng Ho

What did Dr. Tefferi tell patients at the MPN Bay Area Conference today? He's the one who knows whether imet by itself shows any signs of being approvable for blood cancers. At the Shay lab we showed that imet works in a dish (which is nothing, even Vitamin C is a miracle treatment in a dish...if th...
by cheng_ho
Fri Sep 09, 2016 6:20 pm
Forum: ImetelChat
Topic: Link to EU ODD mtg kindly provided by Anne YMB
Replies: 7
Views: 4159

Re: Link to EU ODD mtg kindly provided by Anne YMB

Thanks Scott. Obviously I don't know what the EMA is talking about, because they don't release their meeting minutes for over a month (wonder how many times they get rewritten over that time...) I was just passing on the SA discussion.
by cheng_ho
Thu Sep 08, 2016 8:51 pm
Forum: ImetelChat
Topic: Link to EU ODD mtg kindly provided by Anne YMB
Replies: 7
Views: 4159

Re: Link to EU ODD mtg kindly provided by Anne YMB

Now on SA they're saying the ODD application had nothing to do with imet. Just more random noise...
by cheng_ho
Wed Sep 07, 2016 2:55 am
Forum: ImetelChat
Topic: Link to EU ODD mtg kindly provided by Anne YMB
Replies: 7
Views: 4159

Re: Link to EU ODD mtg kindly provided by Anne YMB

Looks like there must have been some action at the EMA. Too bad they're so nontransparent, it usually takes a month to get the meeting minutes.
by cheng_ho
Tue Sep 06, 2016 4:42 pm
Forum: ImetelChat
Topic: Is Taz on here?
Replies: 10
Views: 5009

Is Taz on here?

Taz, what's the exact name of that patient FB group? I don't get anything when I search on "MPD Myeloprolferative". Thanks.
by cheng_ho
Tue Sep 06, 2016 4:40 pm
Forum: ImetelChat
Topic: Sept 16 Tefferi talk
Replies: 13
Views: 6356

Re: Sept 16 Tefferi talk

Tefferi is fine, he fought against the big pharma push for JAK inhibitors. He's totally focused on getting something that works. As far as the conference goes, there's no way to give patients data without it getting to investors. And there's no way to help patients if the patients don't know what tr...
by cheng_ho
Sun Sep 04, 2016 4:46 pm
Forum: ImetelChat
Topic: Sept 16 Tefferi talk
Replies: 13
Views: 6356

Re: Sept 16 Tefferi talk

this meeting is about informing patients, not investors.
There is no way to separate the two. If Tefferi gives patients news on drug effectiveness, investors will know as well (especially those investors that send someone to the meeting).
by cheng_ho
Wed Aug 31, 2016 7:34 pm
Forum: ImetelChat
Topic: Sdrawkcabeman: the pediatric waiver is a concrete marker of progress towards EU market authorization
Replies: 4
Views: 4908

Re: Sdrawkcabeman: the pediatric waiver is a concrete marker of progress towards EU market authorization

Maybe JNJ will just send one of those iPad remotes to ASH with Tefferi's face on it... he has to be bursting to say something by now, good or bad.
by cheng_ho
Wed Aug 31, 2016 7:32 pm
Forum: ImetelChat
Topic: Sept 16 Tefferi talk
Replies: 13
Views: 6356

Re: Sept 16 Tefferi talk

Yeah, thanks Tangken. Now I know which day to take my anti-depressant Rhodiola supplement :mrgreen:

(Assuming that anything is actually released of course, I'm still remembering ASCO where I was way too optimistic.)
by cheng_ho
Mon Aug 29, 2016 10:25 pm
Forum: ImetelChat
Topic: Need an efficient process for obtaining transformative drugs before approval
Replies: 23
Views: 10532

Re: Need an efficient process for obtaining transformative drugs before approval

Wealthy people don't use "right to try"... they simply leave and use overseas clinics. That's why no one has set a legal precedent, those with enough lawyers use their Gulfstreams instead.
by cheng_ho
Mon Aug 29, 2016 10:23 pm
Forum: ImetelChat
Topic: Sept 16 Tefferi talk
Replies: 13
Views: 6356

Re: Sept 16 Tefferi talk

Anne claims that Tefferi is speaking on Sept 17. (Of course she also claimed that Jannsen had posted a GERN press release... she was reading some small Mexican web site and couldn't tell where she was. We're all way too old :mrgreen:
by cheng_ho
Mon Aug 29, 2016 10:21 pm
Forum: ImetelChat
Topic: AML 2H 2016?
Replies: 3
Views: 1983

Re: AML 2H 2016?

The fact that it disappeared and wasn't mentioned in the last CC is disturbing.
by cheng_ho
Mon Aug 29, 2016 10:20 pm
Forum: ImetelChat
Topic: Sdrawkcabeman: the pediatric waiver is a concrete marker of progress towards EU market authorization
Replies: 4
Views: 4908

Re: Sdrawkcabeman: the pediatric waiver is a concrete marker of progress towards EU market authorization

We went over this two months ago when it came out. All this did was say that Jannsen doesn't have to test in kids for a geriatric medicine. It's good as far as it goes, but it has nothing to do with approval.... and it's from June.
by cheng_ho
Wed Aug 24, 2016 3:27 pm
Forum: ImetelChat
Topic: Sept 16 Tefferi talk
Replies: 13
Views: 6356

Sept 16 Tefferi talk

Anyone know if his talk will be posted online?
by cheng_ho
Thu Aug 04, 2016 4:23 pm
Forum: ImetelChat
Topic: New Shay lab paper
Replies: 4
Views: 2193

Re: New Shay lab paper

Good point, Fisher, imet often shows an effect long before it "should"... somehow interfering with telomerase, interferes with cell division long before the telomeres shorten. If we understood exactly how we might just use that effect and forget the telomere shortening entirely :mrgreen: