ImetelChat

I think we might see some activity on the following fronts: 1. Announcement of first patient dosed (imminent) along with an update of addition of new sites (North Dakota, Israel etc as outlined in new side presentation) along with changes in status to active in sites now designated as completed or i...

Yes, I have definitely seen them do this in the past. bp

As everyone knows the MF clinical trials site was updated on in July to reflect the addition of a single Italian site (that interestingly was the source of a study suggesting MOS of 22 months). Also during this time period Geron would have had to initiated application for fast track (FT is initiated...

rccola335, I think your math is correct and the total number of patients is as you say 225 but since the first 55 are not randomized, it is reasonable to suggest that part I will lack the statistical validity required by the FDA (no p value or Kaplan Meier curves). Part II should address this, but w...

It seems likely we will know after Friday's presentation if not before. bp

Thanks Ryan, you got to this before I did. It is welcome news. I think have a rolling submission process in place could mean that time to approval following the FDA meeting 1st quarter could be short. bp

Here's the link: http://ir.geron.com/news-releases/news- ... imetelstat bp

Thank you Jingle, Buc and G., Jingledsassy, it is my sincerest hope that I am not the lead lemming. Thank you all for your support. bp

Kmall, well you have made a virtual trip around the world to our benefit and to the benefit of patients who may benefit from all of your efforts. Now on to the real world (I don't know if you realize that you are making a metaphorical evolution to RWD!). I salute your efforts to bring the Imetelstat...

Fellow board members, In a wild and perhaps unattainable hope, I have culled what appear to be the over 6500 bogus "requests" for posting privileges. To those (and it could only be one person for all I know) who are trying to destroy this board, I ask you in the kindest way to leave us alone and all...

Why was there a late addition of an Italian site to the MF trial (which was no longer enrolling patients)? Well one might speculate that the "outlier" study: "18.Palandri F, Elli EM, Polverelli N, Bonifacio M, Benevolo G, Abruzzese E, Bergamaschi M, Tieghi A, Iurlo A, Crugnola M, Cavazzini F, Binott...

From Geron's "career opportunities" posting: "The Clinical Project Manager (CPM) will manage one or more allocated Phase I through IV Clinical Trials that may be local, regional or global in scope. The CPM will be 100% accountable for the success of their projects." AFAIK, there is no P I and no P I...

I was pleased to get a prompt response from Jacob. The "completed" designation applies to part I of the study. I would hope these sites will be participating in part II but unless/until the clinical trials site is further updated we won't know. To summarize, "completed" does not mean those sites are...

There is an understandable amount of confusion in my mind as to the actual number of sites that will be actively enrolling in Part II of the P III study. Those listed as "completed" on the surface look like they have completed enrollment in part II and are ready to treat. However, I don't know if th...

Hunt, thanks for reposting this from YMB. I stiglg6 has followed Geron closely and made some interesting and valuable observations and while happy with the repost, he was not happy with the repost being on my moderated site. To me that is unfortunate. He has taken issue with me over my contention th...

Back in the USA! Sorry for the radio silence, have been on a long anticipated retirement trip of a couple of weeks. Also have been trying to deal with the now several thousand bogus registration attempts. Someone (s) want to make this site unusable. Can only assume its is some form of short attack s...

Will be out of the country for a couple of weeks. Would appreciate it if any of our regulars can keep the board up to date. There is a good post from Stig on YMB and recent good discussions on SA. Best Wishes, bp

Thanks 1boardersooner, I can't take credit for that nice summation, it belongs to Ryan, a long time contributor. bp