Search found 377 matches

by rccola335
Mon Jun 24, 2024 3:44 am
Forum: ImetelChat
Topic: Where we are at
Replies: 3
Views: 222

Where we are at

Impress is in phase 2 and paused for a midpoint review - I do not recall midpoint reviews for MDS or MF - we have seen the positive news from QIMR regarding their treatment of patients in the trial (and also the new discovery of Ferroptosis) -Imetelstat is approved for low risk MDS and went through ...
by rccola335
Sat Jun 22, 2024 9:08 pm
Forum: ImetelChat
Topic: Geron website says looking for partners
Replies: 6
Views: 999

Re: Geron website says looking for partners

My guess - it is providing cover when a potential move happens so people can’t say other companies didn’t have an opportunity to make a pitch - can’t think this would be for any other reason
by rccola335
Fri Jun 21, 2024 1:14 pm
Forum: ImetelChat
Topic: New video
Replies: 4
Views: 1168

Re: New video

yes - they really spend a long time discussing imetelstat and the high risk success is huge - if this pause shows definitive success with imetelstat I could see approval for this usage - maybe that is what scarlett meant by us investors being able to ride of into the sunset soon
by rccola335
Thu Jun 20, 2024 9:38 pm
Forum: ImetelChat
Topic: New video
Replies: 4
Views: 1168

New video

by rccola335
Thu Jun 20, 2024 3:03 am
Forum: ImetelChat
Topic: Stealth Study Update
Replies: 8
Views: 1860

Re: Stealth Study Update

Yes the Impress trial
by rccola335
Thu Jun 20, 2024 1:42 am
Forum: ImetelChat
Topic: Stealth Study Update
Replies: 8
Views: 1860

Re: Stealth Study Update

I emailed Geron - we are at the half way point review that was planned - I believe this is what we had been told would happen in January 2024 and was delayed due to slow enrollment - so I would expect some really good news or bad news coming soon
by rccola335
Wed Jun 19, 2024 4:10 am
Forum: ImetelChat
Topic: Stealth Study Update
Replies: 8
Views: 1860

Re: Stealth Study Update

my very strong guess is the Impress trial will continue to enroll and is only paused for a planned safety/efficacy review
by rccola335
Sun Jun 16, 2024 2:12 am
Forum: ImetelChat
Topic: EHA
Replies: 13
Views: 2209

Re: EHA

they said regarding MDS trial at EHA - they could not determine survival months in the non imetelstat arm
by rccola335
Fri Jun 14, 2024 11:51 pm
Forum: ImetelChat
Topic: from abstract of EHA presentation today!
Replies: 3
Views: 834

Re: from abstract of EHA presentation today!

nothing new - that is why Geron did not do a PR for it - I bet we get an update early next week on the Impress trial
by rccola335
Fri Jun 14, 2024 5:17 pm
Forum: ImetelChat
Topic: Ode to a Duck
Replies: 6
Views: 1360

Re: Ode to a Duck

I sent an email to Geron PR - they won’t give me the answer but might prod them to make a public disclosure
by rccola335
Fri Jun 14, 2024 3:43 pm
Forum: ImetelChat
Topic: EHA
Replies: 13
Views: 2209

EHA

The presentation was this morning - not seeing anything popping up on Twitter
by rccola335
Fri Jun 14, 2024 3:15 am
Forum: ImetelChat
Topic: In total there are 142 users online
Replies: 1
Views: 567

Re: In total there are 142 users online

I think for people who wants serious discussion this is the only place - the yahoo message board has gotten worse over the years and is a waste of time anymore
by rccola335
Thu Jun 13, 2024 2:23 am
Forum: ImetelChat
Topic: AML/HR MDS change in study status, ?good news?
Replies: 7
Views: 1229

Re: AML/HR MDS change in study status, ?good news?

reading the details - this is a 4 month study - if things are closed for further enrollment it won't take long for the last patient to finish

my guess is they feel they have what they need to get phase 3 approved
by rccola335
Wed Jun 12, 2024 9:22 pm
Forum: ImetelChat
Topic: AML/HR MDS change in study status, ?good news?
Replies: 7
Views: 1229

Re: AML/HR MDS change in study status, ?good news?

Uwe is the principal investigator and of course will be at the EHA meeting this week
https://x.com/allgtrials/status/1668561 ... CXgoldHN1Q
by rccola335
Wed Jun 12, 2024 8:57 pm
Forum: ImetelChat
Topic: AML/HR MDS change in study status, ?good news?
Replies: 7
Views: 1229

Re: AML/HR MDS change in study status, ?good news?

https://x.com/qimrb_institute/status/17 ... CXgoldHN1Q

Let me share this again because it is applicable to this thread
by rccola335
Wed Jun 12, 2024 8:32 pm
Forum: ImetelChat
Topic: this study is starting 7/12/2024
Replies: 8
Views: 1504

Re: this study is starting 7/12/2024

Should of posted the link https://clinicaltrials.gov/study/NCT06247787?cond=Aml&term=Imetelstat&rank=2 Would imagine the fact more studies branching off is a good sign Is the impress trial closed due to 1- ineffective - unethical to allow treatment 2 - effective - to the point it is obvious and shou...
by rccola335
Wed Jun 12, 2024 8:09 pm
Forum: ImetelChat
Topic: AML/HR MDS change in study status, ?good news?
Replies: 7
Views: 1229

Re: AML/HR MDS change in study status, ?good news?

this is what I have been saying - we are getting some answers soon for the value of imetelstat - this is due to the MF and AML studies - this is why no need to take on a partner in europe when the company will be sold before the end of the year - and thus "we get to ride off into the sunset"
by rccola335
Wed Jun 12, 2024 7:59 pm
Forum: ImetelChat
Topic: AML/HR MDS change in study status, ?good news?
Replies: 7
Views: 1229

Re: AML/HR MDS change in study status, ?good news?

https://clinicaltrials.gov/study/NCT055 ... aml&rank=1

I was looking at this earlier - it was a year ago the first person enrolled - says we are at 23 - this was updated today
by rccola335
Wed Jun 12, 2024 5:50 pm
Forum: ImetelChat
Topic: this study is starting 7/12/2024
Replies: 8
Views: 1504

this study is starting 7/12/2024

A Study to Find the Highest Dose of Imetelstat in Combination With Fludarabine and Cytarabine for Patients With AML, MDS or JMML That Has Come Back or Does Not Respond to Therapy