Search found 550 matches

by LWS
Fri Mar 01, 2024 4:43 pm
Forum: ImetelChat
Topic: Pfizer's big push into the Oncology space
Replies: 1
Views: 497

Re: Pfizer's big push into the Oncology space

Imetelstat works (safe and effective) and is proven for blood cancers in a variety of ways (note KOLs and ODAC meeting March 14th). Pfizer's acquisition ($43B) will increase the interest in and value of Imetelstat. The potential in combinations and chemotherapy is vast for many cancers, both blood ...
by LWS
Wed Feb 28, 2024 7:11 pm
Forum: ImetelChat
Topic: PPS
Replies: 73
Views: 129466

Re: PPS

Some comments from Feb. 28 to ponder. March 14 (ODAC meeting) is the next critical date. ====================================  Geron Corporation Reports Business Highlights and Fourth Quarter and Full Year 2023 Financial Results February 28, 2024 June 16, 2024 PDUFA date for imetelstat NDA for the t...
by LWS
Wed Feb 28, 2024 3:51 pm
Forum: ImetelChat
Topic: PPS
Replies: 73
Views: 129466

Re: PPS

I will try to listen to the Conference Call later today. Is there anything that is forward looking and encouraging (for those that listened live)?
by LWS
Fri Feb 23, 2024 10:27 pm
Forum: ImetelChat
Topic: PPS
Replies: 73
Views: 129466

Re: PPS

Press Release Details Geron to Announce Fourth Quarter and Full-Year 2023 Financial Results on February 28, 2024 FOSTER CITY, Calif.--(BUSINESS WIRE)-- Geron Corporation (Nasdaq: GERN), a late-stage clinical biopharmaceutical company, announced that it will release its fourth quarter and full-year ...
by LWS
Fri Feb 23, 2024 7:29 pm
Forum: ImetelChat
Topic: FDA v. Geron
Replies: 18
Views: 3381

Re: FDA v. Geron

Since the list of negatives has not been added to, I am assuming that there is nothing important or credible to be added. We will hear something on Feb. 28, with the ODAC meeting (March 14) highly anticipated. We would like to know more about that meeting's structure and the KOLs (and others) that ...
by LWS
Thu Feb 22, 2024 4:06 pm
Forum: ImetelChat
Topic: Blood
Replies: 3
Views: 818

Re: Blood

bp --- Later today, I will go back and modify the post that contains "comments regarding blood shed by violence ", as you suggest. As far as Imetelstat goes, so goes ODAC and the KOLs that they will bring into this discussion. March 14th is only 3 weeks away, and I believe there will be some commen...
by LWS
Wed Feb 21, 2024 9:23 pm
Forum: ImetelChat
Topic: THANK YOU IMETELCHAT BOARD !!!!!
Replies: 19
Views: 1850

Re: THANK YOU IMETELCHAT BOARD !!!!!

Kmall -- The subject here is blood (blood cancers, horseshoe crab blood, blood of our allies). All are important. The FDA is also of great importance and needs to be allowed to operate based upon the successful trials and patients' needs. We are talking about humanity, and a functional FDA in a dem...
by LWS
Wed Feb 21, 2024 7:15 pm
Forum: ImetelChat
Topic: THANK YOU IMETELCHAT BOARD !!!!!
Replies: 19
Views: 1850

Re: THANK YOU IMETELCHAT BOARD !!!!!

Kmall --- I totally agree with you. I thought about this for a longtime, and decided that we have such problems, because the 'good-guys' tend to be very quiet. Everything worthwhile for humanity is on the line. After-the -fact is too late.
by LWS
Wed Feb 21, 2024 6:33 pm
Forum: ImetelChat
Topic: THANK YOU IMETELCHAT BOARD !!!!!
Replies: 19
Views: 1850

Re: THANK YOU IMETELCHAT BOARD !!!!!

This is another off-subject post. I doubt if anyone on this board would disagree with the fright, bewilderment and the challenge to the USA. "United we stand, divided we fall". Blood is important to all species. This board is especially interested in human blood transfusions, at this point in time....
by LWS
Wed Feb 21, 2024 12:47 am
Forum: ImetelChat
Topic: Bayer's deep pockets running dry.....
Replies: 1
Views: 438

Re: Bayer's deep pockets running dry.....

JNJ with talcum powder; Bayer with Round-up. There were some very bad decisions made here, which in someways affected Geron and Imetelstat in the past and will in the future.
by LWS
Mon Feb 19, 2024 11:08 pm
Forum: ImetelChat
Topic: FDA v. Geron
Replies: 18
Views: 3381

Re: FDA v. Geron

Thank you bp for the reference These limited criticisms of Imetelstat are characterized as a "soft endorsement". I suspect that the KOLs (March 14th ODAC meeting) will have some "strong endorsements". These are early days in the life and uses of Imetelstat. Some prefer to wait and see (very conserv...
by LWS
Mon Feb 19, 2024 8:30 pm
Forum: ImetelChat
Topic: FDA v. Geron
Replies: 18
Views: 3381

Re: FDA v. Geron

Negatives???? I do not have access to the Mayo editorial. With any new and transitional medicine (Imetelstat) not everything can be known in the early stages. Some features will be uncovered (like 2 ways to kill cancer cells) that were not known earlier (some positive and, perhaps, some negative). ...
by LWS
Mon Feb 19, 2024 3:48 pm
Forum: ImetelChat
Topic: FDA v. Geron
Replies: 18
Views: 3381

Re: FDA v. Geron

The Medical Negatives for Imetelstat Continued The Positives: 1/Transfusion independence 2/ Overall Survival Time 3/ Disease modification 4/ Two ways to kill cancer cells (MOA) -- normal cells OK 5/ Off label uses (in combination --- chemotherapy and other promising combinations when approved) 6/ V...
by LWS
Sun Feb 18, 2024 6:22 pm
Forum: ImetelChat
Topic: THANK YOU IMETELCHAT BOARD !!!!!
Replies: 19
Views: 1850

Re: THANK YOU IMETELCHAT BOARD !!!!!

I signed the petition. Kmall -- In both cases, the FDA is in focus. We all agree that the FDA delays are unwarranted and unnecessary (both horseshoe crabs & blood cancers). I believe that the KOLs will be overwhelmingly positive (March 14th) supporting Imetelstat, and the FDA will follow ODAC's rec...
by LWS
Sun Feb 18, 2024 4:41 pm
Forum: ImetelChat
Topic: THANK YOU IMETELCHAT BOARD !!!!!
Replies: 19
Views: 1850

Re: THANK YOU IMETELCHAT BOARD !!!!!

The FDA in Focus Kmall - The "correlation" with the FDA, one way or the other, has been discussed on this board for a long time. There has been much speculation about why Imetelstat has been "derailed" and not granted "priority review". Some have suggested "shenanigans", while others have suggested...
by LWS
Fri Feb 16, 2024 6:55 pm
Forum: ImetelChat
Topic: PPS
Replies: 73
Views: 129466

Re: PPS

The PPS for Geron is a Mystery As far as I can tell, from what I read, Imetelstat is medically proven to be a very good medicine for a variety of blood cancer conditions (alone, combinations, ongoing trials, etc.). Apparently, many large institutions are accumulating Geron's stock. There are no "sh...
by LWS
Thu Feb 15, 2024 3:50 pm
Forum: ImetelChat
Topic: FDA v. Geron
Replies: 18
Views: 3381

Re: FDA v. Geron

Call for Medical Negatives Concerning Imetelstat This thread was created to list medical negatives that would reduce the chances of ODAC's positive recommendations (from March 14th Imetelstat meeting). The conclusion that I have come to is that the list has no items because none exist. There have b...
by LWS
Wed Feb 14, 2024 7:15 pm
Forum: ImetelChat
Topic: PPS
Replies: 73
Views: 129466

Re: PPS

PPS to be Determined by ODAC (March 14th Meeting) Recommendation to FDA There is little doubt now (none, as far as I am concerned) that the NDA for Imetelstat will be granted. My $4 PPS prediction by Valentines Day was premature. Goldman Sachs still has a "Buy" on Geron with a $4 price target. The ...
by LWS
Tue Feb 13, 2024 5:09 pm
Forum: ImetelChat
Topic: ADCOM
Replies: 96
Views: 288685

Re: ADCOM

ODAC Composition We know that ODAC (Oncology Data Advisory Committee to the FDA) will meet on March 14th, 2024 and the subject will be Imetelstat. This is their first meeting since Nov. 16, 2023. John Scarlett suggested that the current ODAC group is more flexible than prior groups (fireside chat)....
by LWS
Mon Feb 12, 2024 4:12 pm
Forum: ImetelChat
Topic: Everyone catch this one last night?
Replies: 5
Views: 1329

Re: Everyone catch this one last night?

Kmall -- This exposure highlights the interest in fighting cancer (remember the Cancer Moonshot). Imetelstat should be in great demand as a proven blood cancer medicine that is needed now (patients, investors, KOLs, potential partners) across the board. The game was one of the best ever. ==========...