Search found 601 matches
- Wed Apr 24, 2024 1:10 am
- Forum: ImetelChat
- Topic: 12-2, take the win right?
- Replies: 10
- Views: 3848
Re: 12-2, take the win right?
The side effect dangers (specifically Cytopenias and Nuetropenias) were discussed on March 14th. ODAC and others (blood cancer experts) put this problem into proper prospective (manageable and can be eliminated in a short time). The problem seems to be that not all benefit. The side effects can be ...
- Tue Apr 23, 2024 7:26 pm
- Forum: ImetelChat
- Topic: PPS
- Replies: 88
- Views: 137924
Re: PPS
There is much activity in both Geron's and MAIA's PPS. IMHO both will be great successes and will find some ways to work together for common goals. Today they are moving in opposite directions. ------------------------------------------------------------- NYSE American - Nasdaq Real Time Price•USD ...
- Mon Apr 22, 2024 6:52 pm
- Forum: ImetelChat
- Topic: PPS
- Replies: 88
- Views: 137924
Re: PPS
No one can cite a case where an ODAC (Oncology Data Advisory Committee) recommendation was rejected by the FDA. If it ever happened, it wasn't any time recently. The FDA has no reason to go against the advice of their blood cancer experts that I can imagine. Patients need treatment and Imetelstat i...
- Sat Apr 20, 2024 7:28 pm
- Forum: ImetelChat
- Topic: PPS
- Replies: 88
- Views: 137924
Re: PPS
I believe that we will get approval from the FDA based upon the long history of ODAC positive recommendations being accepted. Why would the FDA oppose their own blood cancer experts? There are no medical reasons, and I don't see any shenanigans or conspiracies. Let's get Imetelstat over the finish-l...
- Sat Apr 20, 2024 4:03 pm
- Forum: ImetelChat
- Topic: PPS
- Replies: 88
- Views: 137924
Re: PPS
Some Thoughts: Dr. Feller's presentation at the ODAC meeting (March 14th) was excellent. Dr. Scarlett will not sell the company any time soon because of the unlimited opportunities with combinations and partners. Some believe that Big Phramas are influencing ("sleeping with") this process . Others ...
- Thu Apr 18, 2024 4:12 pm
- Forum: ImetelChat
- Topic: PPS
- Replies: 88
- Views: 137924
Re: PPS
Longterm Investors & Short-term are Very Different Many on this board don't understand trading stocks for short term profits, especially small biotech companies such as Geron, with no approved (by FDA) medicine. This has little to do with the science or the quality of the medicine. With an approved...
- Wed Apr 17, 2024 7:43 pm
- Forum: ImetelChat
- Topic: Stifel Presentation Today
- Replies: 1
- Views: 640
Re: Stifel Presentation Today
We are all waiting for the formal approval of Imetelstat. As far as I can tell from John Scarlett's comments, everything is on track and ready to go. ODAC recommends (12 YES votes from blood cancer experts, 2 No votes) and the FDA approves. I don't believe that there has ever been any deviation from...
- Wed Apr 17, 2024 6:43 pm
- Forum: ImetelChat
- Topic: RYTELO
- Replies: 4
- Views: 1660
Re: RYTELO
Stifel Oncology Forum today very positive (replay now available). #1 take away (beyond transfusion independence) --- "Dynamic Increase of Hemoglobin".
- Tue Apr 16, 2024 12:49 am
- Forum: ImetelChat
- Topic: PPS
- Replies: 88
- Views: 137924
Re: PPS
As investors, now is the time to focus on the PPS. The uniqueness of Rytelo (imetelstat) as a treatment for blood cancers (starting with transfusion independence) is just beginning to be understood as very beneficial now (by itself) and as a treatment, building component, research tool, and in some...
- Mon Apr 15, 2024 4:23 pm
- Forum: ImetelChat
- Topic: RYTELO
- Replies: 4
- Views: 1660
Re: RYTELO
FOSTER CITY, Calif.--(BUSINESS WIRE) -- Geron Corporation (Nasdaq: GERN), a late-stage clinical biopharmaceutical company, announced that John A. Scarlett, M.D., Geron’s Chairman and Chief Executive Officer, is scheduled to present at the following virtual investor conferences: Stifel’s 2024 Virtua...
- Fri Apr 12, 2024 4:08 pm
- Forum: ImetelChat
- Topic: PPS
- Replies: 88
- Views: 137924
Re: PPS
I believe we can finally concentrate on the PPS. ODAC has spoken and the FDA always accepts their positive, overwhelmingly good recommendations (12 yes including blood cancer experts, 2 no ). I believe we are close to $4 PPS, and moving higher. Off-label uses will come into focus. =================...
- Thu Apr 11, 2024 5:11 pm
- Forum: ImetelChat
- Topic: RYTELO
- Replies: 4
- Views: 1660
Re: RYTELO
There is no medicine that does what Rytelo (imetelstat) can do as a stand alone medicine (transfusion independence, improved quality of life, longer life, disease modification, remissions, etc.). On approval (now a formality) off label uses will be suggested and tested. High on the list will be chem...
- Mon Apr 08, 2024 6:37 pm
- Forum: ImetelChat
- Topic: FDA v. Geron
- Replies: 35
- Views: 9570
Re: FDA v. Geron
In the case of ODAC (Oncology Drug Advisory Committee) when they recommend positively and overwhelmingly (12 Yes to 2) the FDA has NEVER rejected their expert advise. I know of no blood cancer oncologist that has spoken against RYTELO (Imetelstat). Many have spoken publicly on its behalf. NOTE: Of ...
- Sat Apr 06, 2024 10:36 pm
- Forum: ImetelChat
- Topic: RYTELO
- Replies: 4
- Views: 1660
Re: RYTELO
MIAMI, FLORIDA (March 14, 2024) – Dr. Mikkael Sekeres is an expert in blood cancers at Sylvester Comprehensive Cancer Center - University of Miami Health System. He served on the Oncologic Drugs Advisory Committee (ODAC) for the trial that led to imetelstat vote of support at the FDA today. Imetels...
- Sat Apr 06, 2024 7:04 pm
- Forum: ImetelChat
- Topic: 12-2, take the win right?
- Replies: 10
- Views: 3848
Re: 12-2, take the win right?
We know exactly what will happen. ODAC has recommended Imetelstat (March 14th) and the FDA always accepts overwhelmingly positive votes (12 YES votes from blood cancer oncologists, 2 NO votes from others). This is not controversial. Imetelstat kills cancer stem-cells in 2 ways and is needed now by ...
- Fri Apr 05, 2024 7:14 pm
- Forum: ImetelChat
- Topic: FDA v. Geron
- Replies: 35
- Views: 9570
Re: FDA v. Geron
The Chair (Ravi) was not up to speed on the importance of Imetelstat to the blood cancer world as a vital 'tool' in transfusion control and well beyond (quality of life, increased survival time, disease modification, combinations, hemoglobin increases ). I suspect he is there by now. ==============...
- Thu Apr 04, 2024 4:02 pm
- Forum: ImetelChat
- Topic: More JnJ Trouble on The Horizon?
- Replies: 1
- Views: 560
Re: More JnJ Trouble on The Horizon?
Turn off the SUN. It causes cancer. The alternatives are difficult to find. Many things cause cancer if you get too much. What is a safe level? (benefit vs. risk again) New, more sensitive sensors are always being invented.
- Tue Apr 02, 2024 6:47 pm
- Forum: ImetelChat
- Topic: FDA v. Geron
- Replies: 35
- Views: 9570
Re: FDA v. Geron
Imetelstat is a breakthrough blood cancer medicine that works for many today, and has almost unlimited potential (kills cancer stem-cells in two ways) in combinations going forward. The 12 YES, 2 NO votes was 100% favored by the ODAC oncology hematologists. “ While a significant minority of pa...
- Sun Mar 31, 2024 6:14 pm
- Forum: ImetelChat
- Topic: 12-2, take the win right?
- Replies: 10
- Views: 3848
Re: 12-2, take the win right?
The benefits of Imetelstat out weigh the risks (not even close) All of the important negatives are temporary and reversible for both responders and non-responders. Obviously, more research is required (partners are a consideration), but that is not a reason to deny it to those who can benefit today...
- Fri Mar 29, 2024 8:33 pm
- Forum: ImetelChat
- Topic: Hundreds of views every day
- Replies: 3
- Views: 1175
Re: Hundreds of views every day
The Die is Cast Certainly, JS knows more than he is telling us about partners and buyouts. There seems to be a 'Geron-factor' (some would say, a 'Geron-curse') with a level of uncertainty that is holding the PPS at these levels. CKTC found 2 cases (ODAC recommended, FDA rejected). If possible (curi...