Search found 9 matches

by Edward
Tue May 18, 2021 3:31 pm
Forum: ImetelChat
Topic: I think the best way to deal with this:
Replies: 15
Views: 5316

Re: I think the best way to deal with this:

Sorry if this is missing something obvious, but aren’t there free message board services we could use? I’d hate for anyone to spend money on hosting if it can be avoided.
by Edward
Wed Mar 17, 2021 6:37 pm
Forum: ImetelChat
Topic: That was a shock
Replies: 7
Views: 4781

Re: That was a shock

Hey Ryan, thanks for the different perspective. Would you mind sharing where you’re getting those market cap projections from? And what sort of timeframe you’re expecting for it to scale up to that? I hope to re-invest some day (closer to commercialization), so I’d love to be wrong about what the fu...
by Edward
Sat Mar 13, 2021 8:33 am
Forum: ImetelChat
Topic: That was a shock
Replies: 7
Views: 4781

Re: That was a shock

I can now see why so many people have lost faith in Geron as a company. Whether you want to call it bad luck, a JNJ conspiracy, or mismanagement, the end result is the same. And the stock will be diluted to the point where the upside is all but erased. There’s no shortage of positive sentiment out t...
by Edward
Sun Jan 10, 2021 11:32 pm
Forum: ImetelChat
Topic: short interest
Replies: 17
Views: 8466

Re: short interest

Thanks, I was really wondering about that. If shorts were able to cover on 25 mil shares and the price only performed as it did then it would be pretty concerning.
by Edward
Thu Dec 10, 2020 12:23 am
Forum: ImetelChat
Topic: Dr. Scarlett has done a great job differentiating...
Replies: 4
Views: 3085

Re: Dr. Scarlett has done a great job differentiating...

Yeah, I’m getting deeply concerned to be honest. I don’t doubt that imetelstat can still get approval, but it seems like the commercial prospects are shrinking, the wait is still very long, and there won’t be much encouraging news to boost the stock in the meantime. Hard to make an argument that thi...
by Edward
Tue Dec 08, 2020 9:39 pm
Forum: ImetelChat
Topic: CRSPR
Replies: 5
Views: 2996

Re: CRSPR

Is it a lower or higher bar to demonstrate improvement in patients who are treatment refractory? Could be one argument for the study designs to date. At least in my field, if someone comes in with mild symptoms we know they’re a lot less likely to show a big treatment effect. Or maybe its a higher b...
by Edward
Tue Dec 08, 2020 5:03 pm
Forum: ImetelChat
Topic: CRSPR
Replies: 5
Views: 2996

Re: CRSPR

Wouldn’t stopping the cancer proliferation with Imetelstat be worth doing right off the bat, followed by (or concurrent with) symptom management? Or will Constellation’s drug handle that well enough by itself?
by Edward
Tue Dec 08, 2020 5:53 am
Forum: ImetelChat
Topic: Article that addresses challenges to enrollment
Replies: 3
Views: 2172

Re: Article that addresses challenges to enrollment

bp, are/were you in HMS somewhere? Not trying to dox myself but I work at an affiliated hospital. I’ve thought about using that connection to bug Steensma about Imetelstat but figured it would be completely unprofessional and I’m not even a medical doctor, let alone in heme/onc.