Search found 2069 matches
- Tue Mar 18, 2025 1:51 am
- Forum: ImetelChat
- Topic: Survival studies in MF revisited
- Replies: 3
- Views: 671
Re: Survival studies in MF revisited
Lacour, enrollment to 100% is not required nor likely. It probably has nothing to do with Dr. Scarlett but rather a desire to have a watertight presentation of data for the FDA. They will follow the protocol to the letter unless the Data Safety Monitoring Board stops the study for efficiency. (They ...
- Mon Mar 17, 2025 8:11 pm
- Forum: ImetelChat
- Topic: Survival studies in MF revisited
- Replies: 3
- Views: 671
Survival studies in MF revisited
It looks like about 35% of BAT (non Imetelstat) R/R MF patients are dead between 6 and 10 months in these studies. Recall that the current study has a rolling enrollment, that is they don’t all leave the starting gate at the same time but each patient leaves the gate when there is “intention to trea...
- Mon Mar 17, 2025 3:31 pm
- Forum: ImetelChat
- Topic: An example of a reasonable discussion that got highjacked by the amygdala
- Replies: 1
- Views: 491
- Mon Mar 17, 2025 3:29 pm
- Forum: ImetelChat
- Topic: An example of a reasonable discussion that got highjacked by the amygdala
- Replies: 1
- Views: 491
An example of a reasonable discussion that got highjacked by the amygdala
We have seen many examples of the FDA doing good work. But like other organizations that impact medical research it is not above self examination. I think an overt example of this has affected us all and is not a “left/right” issue so please don’t go zero to 60 in one second over this. I submit for ...
- Sat Mar 15, 2025 4:26 am
- Forum: ImetelChat
- Topic: New FDA objectives......who could be against this?
- Replies: 7
- Views: 1743
Re: New FDA objectives......who could be against this?
Shut it down guys, please. There is no question that the FDA is being guided toward a change in focus. Left or right is immaterial to this discussion.
- Sat Mar 15, 2025 3:33 am
- Forum: ImetelChat
- Topic: Letter from Errol
- Replies: 2
- Views: 884
Re: Letter from Errol
Errol’s response, Hi, XXXX. Thank you so much for posting my letter on I-chat. I really appreciated your letter to Dawn! I think they will address all of your questions and concerns in a timely manner. New leadership always feels pressure not to repeat failures of the former. Great big thank you! Er...
- Fri Mar 14, 2025 8:59 pm
- Forum: ImetelChat
- Topic: New FDA objectives......who could be against this?
- Replies: 7
- Views: 1743
Re: New FDA objectives......who could be against this?
I will take it one step further (without getting political). I was once doing volunteer medical work in a third world country. At dinner I noted that the vegetables were perfect and tasted great. I asked my hosts how they accomplished this. The answer was, “that’s simple, we use DDT.” There certainl...
- Fri Mar 14, 2025 8:26 pm
- Forum: ImetelChat
- Topic: The unbearable lightness of being
- Replies: 1
- Views: 541
- Fri Mar 14, 2025 8:16 pm
- Forum: ImetelChat
- Topic: The unbearable lightness of being
- Replies: 1
- Views: 541
The unbearable lightness of being
Clinical trials site for the ongoing MF trial has been updated to show complete pushed out by about another 18 months (June 2028). It appears that if you drink from the Holy Grail, you live a long time.
- Fri Mar 14, 2025 5:50 pm
- Forum: ImetelChat
- Topic: New FDA objectives......who could be against this?
- Replies: 7
- Views: 1743
Re: New FDA objectives......who could be against this?
Hi guys we can definitely have this discussion without making it “political “. I submit for your consideration: trans fatty acids , remember them and carminic acid derived from red ants (eg red dye).
- Fri Mar 14, 2025 2:00 am
- Forum: ImetelChat
- Topic: This is a start, please add. Let’s get ready for May
- Replies: 1
- Views: 860
This is a start, please add. Let’s get ready for May
Dear Dawn, as you can see many posters and stockholders in general need some reassurance. I would encourage you to consider a special letter to stockholders to address how you view the changes in Geron’s leadership and your vision for the future. It has been a long road to reach this point. Transpar...
- Fri Mar 14, 2025 1:24 am
- Forum: ImetelChat
- Topic: Letter from Errol
- Replies: 2
- Views: 884
Re: Letter from Errol
Errol, To be sure your letter will be read by Geron management. I think you can take some comfort in Geron’s approach to physicians as gleaned from the various new positions they have established. I believe your recommendations are already being addressed and I would encourage you to see if Dr. XXXX...
- Fri Mar 14, 2025 1:19 am
- Forum: ImetelChat
- Topic: Letter from Errol
- Replies: 2
- Views: 884
Letter from Errol
One of my correspondents, Errol is undergoing treatment for his hematologic disorder. He has given me permission to share one of his recent letters to me: Hi XXXX I'm not a member of I-chat and not an eloquent writer. I want to share some ideas that you can post at I-chat if you see fit. I believe t...
- Thu Mar 13, 2025 12:40 pm
- Forum: ImetelChat
- Topic: "DAWN OF A NEW ERA!"
- Replies: 5
- Views: 1291
Re: "DAWN OF A NEW ERA!"
Stanley rock nice letter! Am on the road to Kansas City and will post something from “Errol” once I get settled.
- Wed Mar 12, 2025 12:42 am
- Forum: ImetelChat
- Topic: Kudos to Dr. Scarlett
- Replies: 6
- Views: 1349
Re: Kudos to Dr. Scarlett
Kmall, while it ain’t “X”, a lot of folks do read this board (well, maybe not Elon, wouldn’t it be great if he did?) I would not underestimate the weight of your words, both recent and past. There are not too many places for the BOD to take the pulse of those interested in Geron (I do not advise YMB...
- Tue Mar 11, 2025 10:57 pm
- Forum: ImetelChat
- Topic: Kudos to Dr. Scarlett
- Replies: 6
- Views: 1349
Kudos to Dr. Scarlett
John from me, thank you. For those who don’t remember the twists and turns successful navigated by John and his board, let me refresh. The company was trashed by his predecessor, Tom Okarma. John was wise enough to jettison the stem cell business which continues to flail under different management. ...
- Tue Mar 11, 2025 10:33 pm
- Forum: ImetelChat
- Topic: Calling BOD to act
- Replies: 8
- Views: 2836
Re: Calling BOD to act
Looks like the board heard your voices.
- Tue Mar 11, 2025 8:07 pm
- Forum: ImetelChat
- Topic: FWIW--EMA
- Replies: 6
- Views: 1265
Re: FWIW--EMA
You'd better buy some crutches, just in case.
- Tue Mar 11, 2025 4:39 pm
- Forum: ImetelChat
- Topic: FWIW--EMA
- Replies: 6
- Views: 1265
- Tue Mar 11, 2025 3:24 pm
- Forum: ImetelChat
- Topic: Calling BOD to act
- Replies: 8
- Views: 2836
Re: Calling BOD to act
Stanleyrock, The stockholders meeting is coming up in May. This is virtually the only time you can make your (and our) voice heard. There is obviously something in the works, good or bad, hopefully good. EU approval is pending but how much that will help the bottom line is questionable and we should...