Search found 24 matches

by jpheis
Fri Sep 28, 2018 1:57 am
Forum: ImetelChat
Topic: A tough day
Replies: 4
Views: 4220

Re: A tough day

BP- your thoughts are well supported with facts and your input is greatly appreciated. First off, I humbly implore you to remain as the moderator. While the momentary monetary defeat is of great pain (ok shuddering) your contributions and the legacy you have assumed command a greater audience. Your ...
by jpheis
Sat Sep 22, 2018 4:38 am
Forum: ImetelChat
Topic: Recent Blood Advances article
Replies: 1
Views: 3083

Recent Blood Advances article

m Published September 21. I found this via StockTwits so don’t give me credit. Appears to support the MF first thesis. Interesting pursuit of in vivo and in vitro. You guys are smarter then me. I am eager to hear thoughts. Tea leaves, absurd valuations, newbie thesis, and mundane conjecture could us...
by jpheis
Wed Sep 19, 2018 5:10 pm
Forum: ImetelChat
Topic: Why Imbark gets approved
Replies: 7
Views: 8795

Re: Why Imbark gets approved

Phil- nice post. Thank you. I fully agree that MF gets approval first. The recent MF update on clinical trials.org indicates to me that significant impact was realized with 4.7, and perhaps there is a benefit for some/more compromised patients to start at 4.7 then escalating to the higher dose. Add ...
by jpheis
Thu Sep 13, 2018 8:28 pm
Forum: ImetelChat
Topic: For those interested:Janssen Pharma presentation
Replies: 2
Views: 3408

Re: For those interested:Janssen Pharma presentation

Something that caught my attention on the slide that lists Imetelstat as an NME. MF is listed first (blue for NME) and MDS is listed as a line extension(black). So wouldn’t this mean MF goes for NDA first?
by jpheis
Tue Aug 28, 2018 9:21 pm
Forum: ImetelChat
Topic: An appeal from biopearl
Replies: 3
Views: 3759

Re: An appeal from biopearl

BP- I share your sentiment and will gladly contribute. Let us know if Fish Jr provides the hospital info. I’m also happy to contribute to the costs of this site. Fish is a big part of my oversized position and returns in Geron. His raw knowledge was incredible and his belief in Imetelstat was infect...
by jpheis
Mon Jul 23, 2018 11:20 pm
Forum: ImetelChat
Topic: Pediatric Consortium Study
Replies: 2
Views: 3989

Re: Pediatric Consortium Study

I found this on anr2018.org. A Molecularly Driven Pharmacological Approach for Neuroblastoma: Targeting TERT and CKS1b Neuroblastoma is the most common extracrainal solid tumour in childhood. The high risk, metastatic form of neuroblastoma has very poor prognosis, and the survival rate after 5 years...
by jpheis
Fri Jul 13, 2018 12:07 am
Forum: ImetelChat
Topic: New telomerase article
Replies: 8
Views: 17413

Re: New telomerase article

I tried to edit my post but hit a glitch. I wanted to add that I am going off memory at this point and have yet to review previous filings for 203 mention(s).
by jpheis
Fri Jul 13, 2018 12:02 am
Forum: ImetelChat
Topic: New telomerase article
Replies: 8
Views: 17413

Re: New telomerase article

BP/Hoosier/MTB/etc. Look at page 10 and beginning of page 11. I have not seen Delaware Section 203 mentioned in any previous filings. At first glance it appears Geron is electing to abide by 203 yet I question the staying power of the decision in unforeseen events.
by jpheis
Wed Jul 11, 2018 3:43 am
Forum: ImetelChat
Topic: New telomerase article
Replies: 8
Views: 17413

Re: New telomerase article

Ryan- all good points. I am cautious of the short term SP with the dogs circling on the 250mm - but taken holistically the appearance is of perculating binary events. Please take caution to SA rumors as we see they can matriculate to the true essence of a rumor, albeit with good intentions. Please r...
by jpheis
Wed Jul 11, 2018 3:16 am
Forum: ImetelChat
Topic: General Announcement from bio pearl
Replies: 6
Views: 40568

Re: General Announcement from bio pearl

No- thank you. My apologies for not seeing. Looks like my browser pulled a cached version because now I see several updated posts. I am grateful for all that you are doing for this board and your contributions to SA as well. Regards, jpheis
by jpheis
Tue Jul 10, 2018 2:34 pm
Forum: ImetelChat
Topic: General Announcement from bio pearl
Replies: 6
Views: 40568

Re: General Announcement from bio pearl

Biopearl- looks like you have an awesome new article for the library
https://bmccancer.biomedcentral.com/tra ... 018-4633-x
by jpheis
Thu Jun 14, 2018 5:25 am
Forum: ImetelChat
Topic: Goodbye
Replies: 9
Views: 13299

Re: Goodbye

Mark’s passing is heavy to my heart. I am so grateful for his contributions and the diligence he displayed in maintaining an above board forum. His passion for imetelstat was contagious and a main driver behind my outsized emotional and financial involvement in Geron. Bio-thank you taking up the tor...
by jpheis
Wed Jun 06, 2018 4:43 am
Forum: ImetelChat
Topic: Recent Interesting article
Replies: 2
Views: 4680

Re: Recent Interesting article

June 14-August 1 is ASH abstract submission time. Late breakers are Oct 18-30. All abstracts posted Nov 1
by jpheis
Fri Jun 01, 2018 2:54 am
Forum: ImetelChat
Topic: Recent Interesting article
Replies: 2
Views: 4680

Re: Recent Interesting article

Nice find BP. Thank you. I’m not posting much due to a recent imbalance in my life:work ratio but I’m reading. From the outside it looks like a concerted effort to publish MOA. I have yet to decide if there anything to take away from the March 20 update. Authors normally only edit when something sig...
by jpheis
Fri May 18, 2018 4:13 am
Forum: ImetelChat
Topic: EHA
Replies: 3
Views: 4234

Re: EHA

BP- many thanks for the link. If you have the time I would sincerely appreciate your take on the abstract. I am impressed this is oral, as that criteria is far more stringent than a poster. And I am quite aware an abstract and actual presentation likely and most often vary dramatically. I’m tempted ...
by jpheis
Tue Apr 24, 2018 11:05 pm
Forum: ImetelChat
Topic: Clinical trials site shows high risk study primary completion date
Replies: 1
Views: 2488

Re: Clinical trials site shows high risk study primary completion date

Nice find BP. J&J might be looking for Imetelstat’s prospects to divert attention from the settlement on talc.
by jpheis
Sat Mar 31, 2018 1:43 am
Forum: ImetelChat
Topic: Repost from SA by biopearl re recent events
Replies: 2
Views: 4432

Re: Repost from SA by biopearl re recent events

Gratitude BP. I have read through your post multiple times and keep coming back to two questions. 1-what was John’s dose? I can’t remember for the life of me. 2-if only 8 weeks is needed on the MDS TI read out, how soon do we get an update? Theoretically late April the data is complete since the sli...
by jpheis
Mon Mar 26, 2018 11:08 pm
Forum: ImetelChat
Topic: Geron to present at 17th Needham Healthcare Conference on March 27, 2018
Replies: 5
Views: 8498

Re: Geron to present at 17th Needham Healthcare Conference on March 27, 2018

Scott- I have listened to Geron investor conferences since Q4 2014 and historically speaking Scarlett has not used investor conferences as forums for significant new information. New information may require additional disclosure under SEC rules. Scarlett does sometimes expand upon or clarify researc...
by jpheis
Sat Mar 24, 2018 1:17 pm
Forum: ImetelChat
Topic: Continuation of excellent posts by Sdraw on YMB
Replies: 5
Views: 6958

Re: Continuation of excellent posts by Sdraw on YMB

Sdraw is top shelf. He has all the attributes of a Chief Medical Officer with a clear passion for Imetelstat. We should re-post all of his writings into a thread here.