Upcoming Phase 3 MF Trial

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CKTC
Posts: 50
Joined: Sun May 31, 2020 4:26 am

Upcoming Phase 3 MF Trial

Post by CKTC » Wed Jun 17, 2020 4:31 pm

WOW! Dr. Srdan Verstovsek from MD Andersen, the Principal Investigator for Incyte’s COMFORT Phase 3 MF ruxolitinib trial, and the man I call “Dr. Ruxolitinib” as he historically has been the primary apologist for everything related to the drug, is going to be the co-Principal Investigator with Dr. Mascarenhas on the upcoming imetelstat Phase 3 MF trial. Dr. Verstovsek has “worked” with Incyte for years on numerous ruxolitinib trials. This is a very interesting development.

CKTC
Posts: 50
Joined: Sun May 31, 2020 4:26 am

Re: Upcoming Phase 3 MF Trial

Post by CKTC » Wed Jun 17, 2020 11:02 pm

To add a little color to my comment above, Dr. Verstovek has been the Principal Investigator on seven ruxolitinib trials that enrolled over 800 patients, including the Phase 3 studies that won Incyte FDA approval for the drug in Myelofibrosis and Polycythemia Vera. He’s been the lead author on scores of published papers discussing ruxolitinib. Bringing Dr. Verstovek into the imetelstat loop is a savvy move.

FC4364
Posts: 23
Joined: Sun Dec 23, 2018 11:02 pm

Re: Upcoming Phase 3 MF Trial

Post by FC4364 » Thu Jun 18, 2020 1:56 am

CKTC, curious as to where this is posted. I know there are scores of information out there in regards to Imetelstat. Almost impossible to keep up with it - LOL. Thank you

biopearl123
Posts: 1665
Joined: Fri Jul 20, 2018 5:13 pm

Re: Upcoming Phase 3 MF Trial

Post by biopearl123 » Thu Jun 18, 2020 6:14 am

FC4364, Dr. Verstovek is verified as co lead investigator in Geron's presentation today. His CV is as CKTC has outlined. This is very good news and first class institutions are leading the way with Mt. Sinai and MD Anderson. bp

FC4364
Posts: 23
Joined: Sun Dec 23, 2018 11:02 pm

Re: Upcoming Phase 3 MF Trial

Post by FC4364 » Thu Jun 18, 2020 3:17 pm

BP, thank you. Have not had a chance to listen to the presentation and this is prenominal good news. Thanks again. FC

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