https://www.fda.gov/vaccines-blood-biol ... autologous
JNJ dropped the CD with Geron largely because they believed Car-T was the future of cancer treatments. This is a sad turn of events for cancer patients, but probably a good thing for Geron investors.
"The Food and Drug Administration (FDA) has received reports of T-cell malignancies, including chimeric antigen receptor CAR-positive lymphoma, in patients who received treatment with BCMA- or CD19-directed autologous CAR T cell immunotherapies. Reports were received from clinical trials and/or postmarketing adverse event (AE) data sources.
FDA has determined that the risk of T-cell malignancies is applicable to all currently approved BCMA-directed and CD19-directed genetically modified autologous CAR T cell immunotherapies. T-cell malignancies have occurred in patients treated with several products in the class. Currently approved products in this class (listed alphabetically by trade name) include the following:
Abecma (idecabtagene vicleucel)
Breyanzi (lisocabtagene maraleucel)
Carvykti (ciltacabtagene autoleucel)
Kymriah (tisagenlecleucel)
Tecartus (brexucabtagene autoleucel)
Yescarta (axicabtagene ciloleucel)
FDA Investigates Car T Immunotherapies
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Re: FDA Investigates Car T Immunotherapies
This just came out today, Nov 28, 2023.
Re: FDA Investigates Car T Immunotherapies
Abecma - Bristol Meyers Squibb (Celgene)
Breyanzi - Bristol Meyers Squibb
Carvykti - JNJ (Janssen)
Kymriah - Novartis
Tecartus - Gilead (Kite Pharma)
Yescarta - Gilead (Kite Pharma)
https://www.fiercepharma.com/pharma/fda ... -treatment
Wow!!!
Some fairly big M&A deals in pharma these past few years - two of the largest on the back of CAR-t.....
(2017) - Gilead buys Kite Pharma for $11.9B
https://www.gilead.com/news-and-press/p ... 19-billion
(2019) - Bristol Meyers buys Celgene for $74B
https://www.biospace.com/article/done-b ... on-merger/
.....what would Homer say? -Kmall
https://youtu.be/YkLUho5wLLY?si=a-IwnWXDZ1sXlpsa
Breyanzi - Bristol Meyers Squibb
Carvykti - JNJ (Janssen)
Kymriah - Novartis
Tecartus - Gilead (Kite Pharma)
Yescarta - Gilead (Kite Pharma)
https://www.fiercepharma.com/pharma/fda ... -treatment
Wow!!!
Some fairly big M&A deals in pharma these past few years - two of the largest on the back of CAR-t.....
(2017) - Gilead buys Kite Pharma for $11.9B
https://www.gilead.com/news-and-press/p ... 19-billion
(2019) - Bristol Meyers buys Celgene for $74B
https://www.biospace.com/article/done-b ... on-merger/
.....what would Homer say? -Kmall
https://youtu.be/YkLUho5wLLY?si=a-IwnWXDZ1sXlpsa
Last edited by kmall on Tue Nov 28, 2023 11:56 pm, edited 1 time in total.