Iron overload and its complications

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biopearl123
Posts: 1670
Joined: Fri Jul 20, 2018 5:13 pm

Iron overload and its complications

Post by biopearl123 » Sun Apr 18, 2021 9:57 pm

Iron overload doesn't just increase the risk of AML:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4553145/

biopearl123
Posts: 1670
Joined: Fri Jul 20, 2018 5:13 pm

Re: Iron overload and its complications

Post by biopearl123 » Sun Apr 18, 2021 11:30 pm

From the above:

"A separate retrospective review of a US health insurance claims database (1997–2004) also showed that receipt of RBC transfusions significantly increased the risk of iron overload-related complications including cardiomyopathy/heart failure, conduction/rhythm disorders, diabetes, and liver disease [40]. Hospitalization data from the Australian state of Victoria also showed that RBC-TD patients had significantly higher rates of congestive heart failure, bacterial and fungal infections, transformation to AML, and sepsis as cause of death [25]"

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