In fairness

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biopearl123
Posts: 1665
Joined: Fri Jul 20, 2018 5:13 pm

In fairness

Post by biopearl123 » Fri Mar 26, 2021 5:25 pm

If you can access this article you can see that as bad as COVID 19 has been in the US, we are better equipped than many places to deal with it. Our vaccine program has momentum and now will reach 200 million vaccinations in President Biden's first 100 days. Not so for other places:

https://www.washingtonpost.com/world/th ... story.html

Brazil represents one one of many countries where Geron has the Herculean task of running studies. Places like South Korea and Israel are faring better but the challenge of enrollments is daunting and not the fault of Geron's management. I think we need to continue to understand the horrors COVID has wrought and begin to understand how the pandemic has slowed Imetelstat's march to market. (Almost as much as Janssen did)

Last year's shareholder letter discussed the next likely study (high risk MDS/AML) which was put on ice. This is likely what Dr. Scarlett was alluding to in the last quarterly call but really, why the secrecy?? We as shareholders deserve to know the company's further development plans beyond the two struggling PIII's. We deserve an update on the MDS durability data and an explanation as to why this was not provided at ASH. We also need an enlightened FDA ( and DMSB) to allow reevaluation of the current study design (FDA supposed to provide ongoing guidance under rubric of "fast track") to allow for the possibility that both primary and secondary end point could be reached statistically before full enrollment in the MDS study is complete. An acceleration of development (eg assessment of combination studies) is called for as "infrastructure" plans come out of Washington.

We have lost a lot of time at the hands of the Cyclops Janssen and now the Cerberus of Hades, COVID. Enlightened minds should turn to ways to help us make it up. Stay Healthy and be glad you live in this country for any of a thousand reasons. bp

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