Search found 246 matches

by huntingonthebluffs
Sun Jul 25, 2021 12:23 am
Forum: ImetelChat
Topic: the wording is tricky here but important
Replies: 6
Views: 3392

Re: the wording is tricky here but important

Thanks again biopearl123, for taking this deeper and wider as usual! I continue to believe the reason we don’t have a partner, etc. as Dr. John Scarlett has said, the terms are not reflective of Geron/Imetelstat’s value and I suspect the starting point of the stock price will need to be considerably...
by huntingonthebluffs
Mon Jul 19, 2021 5:30 pm
Forum: ImetelChat
Topic: the wording is tricky here but important
Replies: 6
Views: 3392

Re: the wording is tricky here but important

Bottomline for Constellation and Curis, even MAIA, and any others trying to enter this space, they much later to the game than Geron? I wonder are they just looking for additional “targets and hits” per ashah’s link or really trying to go head-to-head with Imetelstat. Disease modification (DM) is a ...
by huntingonthebluffs
Sun May 30, 2021 8:56 pm
Forum: ImetelChat
Topic: The way forward
Replies: 7
Views: 5052

Re: The way forward

There is no problem if donations exceed the goal of $1000. euros. So far only 18 donations have been made so if one values this site and would like to push above the goal, IMO that would be great. With $1000 euros goal achieved, we can all breathe a sigh of relief, however that goal will only cover ...
by huntingonthebluffs
Tue May 25, 2021 5:30 pm
Forum: ImetelChat
Topic: The way forward
Replies: 7
Views: 5052

Re: The way forward

Thank you Fish Jr.! Very thoughtful response and perfectly on target in my view. Also, a big thank you as well to biopearl123 for his many contributions and to ashah for the generous offer to step up to moderate the ImetelChat community going forward!
by huntingonthebluffs
Mon May 24, 2021 9:16 pm
Forum: ImetelChat
Topic: Post to Fish Jr.
Replies: 4
Views: 1586

Post to Fish Jr.

Dear Fish Jr. I am a member on ImetelChat and FWIW, I wanted to share my take on ImetelChat with you. In my opinion, if at all possible the site should be kept up and running for the next few years. I also realize it is a long shot for this to happen given both you and biopearl123 are wanting to ste...
by huntingonthebluffs
Sat May 15, 2021 7:25 pm
Forum: ImetelChat
Topic: I think the best way to deal with this:
Replies: 15
Views: 5319

Re: I think the best way to deal with this:

First, a huge thank you to Fishermangents Sr./Jr. and you for all your time, effort and continuous contributions. I personally can say that this board is the only place I care to post on and find the information and analysis provided here to be of significant value to me but quite likely expect to o...
by huntingonthebluffs
Sun May 09, 2021 2:04 am
Forum: ImetelChat
Topic: In support of Cheng Ho’s arguments
Replies: 3
Views: 2310

Re: In support of Cheng Ho’s arguments

Ha! So granted my hunting analogy was crude at best, but I think both hunting and aiming in the right location is usually far more advantageous than speed to indiscriminate senescence or generalized coverage possibly excessively exacerbating cytopenias. Which I don’t believe was or could be fairly a...
by huntingonthebluffs
Sun May 09, 2021 1:00 am
Forum: ImetelChat
Topic: Partner for European Rights
Replies: 4
Views: 2542

Re: Partner for European Rights

I personally am not opposed to a partnership, however on the boards, we tend to generalize the partnership agreement which leaves so much to ones imagination or not. As we know, not all partnerships workout but they can have advantages and/or disadvantages. As JS/BOD/Geron gains traction in the regu...
by huntingonthebluffs
Fri May 07, 2021 9:09 pm
Forum: ImetelChat
Topic: In support of Cheng Ho’s arguments
Replies: 3
Views: 2310

Re: In support of Cheng Ho’s arguments

Thanks again biopearl for posting these insightful links. This research paper, published in November 2018 and to date has not been updated. One has to wonder if JNJ incorrectly interpreted this information prior to the negative CD. Certainly an interesting paper, however, IMHO the goal seems to be r...
by huntingonthebluffs
Tue Apr 20, 2021 6:39 pm
Forum: ImetelChat
Topic: New Tefferi paper
Replies: 2
Views: 2043

Re: New Tefferi paper

Thanks for sharing. Excellent and very interesting work again by Dr. Ayalew Terreri. Seems like it’s been a while since he’s shown up on our radar like this and clearly provided a significant level of support for Imetelstat. While I appreciate the contribution, It’s a stretch to say Geron blew anyth...
by huntingonthebluffs
Thu Mar 25, 2021 6:55 pm
Forum: ImetelChat
Topic: It all comes down to confidence
Replies: 1
Views: 1589

Re: It all comes down to confidence

Part 2: Over the next couple years Geron will complete building the vertical organization and infrastructure to deliver Imetelstat to patients with hematologic cancers and eventually to patients with other malignancies. Will any BP do it faster and better starting now? Will any BP be more focused on...
by huntingonthebluffs
Thu Mar 25, 2021 6:54 pm
Forum: ImetelChat
Topic: It all comes down to confidence
Replies: 1
Views: 1589

It all comes down to confidence

Part 1: Do you have confidence in this company or not? For me, that is the question, period. I don’t think it is just about what did or didn’t happen to date, what the share price is/is not doing, the CEO, the BOD, the A or B team’s talent and motivation, KOLs, the CRO, shareholders, the drug and as...
by huntingonthebluffs
Tue Aug 25, 2020 10:43 pm
Forum: ImetelChat
Topic: Quote from Dr. Stephen Hahn FDA Commissioner
Replies: 3
Views: 2531

Re: Quote from Dr. Stephen Hahn FDA Commissioner

biopearl123, that is an interesting analogy, as a 35% mortality reduction is an impressive number in this context as is Imetelstat’s results in MOS for R/R MF as well as, TI in MDS. However, I think it might be comparing apples to oranges if you are looking at MOS in R/R MF vs recovery from a virus....
by huntingonthebluffs
Sat Aug 15, 2020 11:34 pm
Forum: ImetelChat
Topic: Re EU MA
Replies: 13
Views: 6640

Re: Re EU MA

biopearI123, think this is a very good discussion to have. I really like and appreciate this thread. This could also be expanded into other considerations given an MA from any entity not just the EMA although it seems obvious that the regulatory agencies work together and try to stay in sync and pro...
by huntingonthebluffs
Wed Jun 17, 2020 6:35 am
Forum: ImetelChat
Topic: Imagine reading this
Replies: 6
Views: 4496

Re: Imagine reading this

Thanks, biopearl for that link regarding the FDA guidelines for allowing a donor to donate blood as it sheds some light on the criticality of the availability of blood for RBCTs and the demand for over 40K RBCTs per day in the US. I am very grateful not to require RBCTs and I believe anyone would ha...
by huntingonthebluffs
Tue Jun 16, 2020 8:13 am
Forum: ImetelChat
Topic: Imagine reading this
Replies: 6
Views: 4496

Re: Imagine reading this

bp, your focus on the number of RBC transfusions (RBCT) seems to me to be a relatively new and un-vetted line of thought for this board and for anyone focusing on the benefits of Imetelstat. I think you are maybe shining a bright light on an issue that should be difficult to ignore and it maybe the ...
by huntingonthebluffs
Sat May 23, 2020 10:11 pm
Forum: ImetelChat
Topic: Thoughts on this interesting take from YMB:
Replies: 10
Views: 5825

Re: Thoughts on this interesting take from YMB:

Given our CEO is shrewd and a risk taker and heavily vested in making the best / right steps in bringing Imetelstat to market in the greatest way possible, I think we can rest assured that there is a lot of “out of the box” thinking going on right now. These discussions certainly include funding, pa...
by huntingonthebluffs
Wed Apr 22, 2020 11:52 pm
Forum: ImetelChat
Topic: Patience and balance are virtues needed for the Geron journey
Replies: 9
Views: 6065

Re: Patience and balance are virtues needed for the Geron journey

Yes, patience is hard in this space and time, as well as elsewhere for some of us, myself included. And I don’t mean to be overly philosophical with these posts and realize with so many people, patients and investors alike, struggling with their interest and participation in Geron / Imetelstat has b...
by huntingonthebluffs
Tue Apr 14, 2020 12:28 am
Forum: ImetelChat
Topic: Patience and balance are virtues needed for the Geron journey
Replies: 9
Views: 6065

Re: Patience and balance are virtues needed for the Geron journey

Thanks bucbeard for your kind response as always. I certainly would feel much more at home on the bluffs in hunting gear than in a lounge chair on Turtle Island but who knows what the impending may bring. And either would be a welcome venue for meeting up with you somewhere in the future. And thanks...
by huntingonthebluffs
Sat Apr 11, 2020 1:25 am
Forum: ImetelChat
Topic: Patience and balance are virtues needed for the Geron journey
Replies: 9
Views: 6065

Re: Patience and balance are virtues needed for the Geron journey

Part 3 of 3: Now we should all come back to face our confirmation biases, especially where our fortunes are at stake. I think a significant part of our CB flows from our nature versus the data, results or ideas presented. However, in regards to our Geron investments, I believe most of us will ultima...