Search found 202 matches
- Sun Jan 17, 2021 8:04 pm
- Forum: ImetelChat
- Topic: Musings on Geron's current and future position
- Replies: 3
- Views: 3159
Re: Musings on Geron's current and future position
Moderna has a large oncology division, working on mRNA vaccines that can be customized against any cell with a mutated antigen.
- Tue Jan 12, 2021 10:45 pm
- Forum: ImetelChat
- Topic: Short interest near all-time highs
- Replies: 0
- Views: 2365
Short interest near all-time highs
It is almost back to where it was in 2018 before the Discontinuation.
High short interest is a good statistical predictor of stock underperformance.
https://www.nasdaq.com/market-activity/ ... t-interest
High short interest is a good statistical predictor of stock underperformance.
https://www.nasdaq.com/market-activity/ ... t-interest
- Fri Jan 08, 2021 7:00 pm
- Forum: ImetelChat
- Topic: New presentation with timelines
- Replies: 2
- Views: 2518
Re: New presentation with timelines
Yes, "topline results" in 2024. We already know the timeline.
What we NEED is some transparency about recruiting so we can see the odds of them meeting the timeline.
What we NEED is some transparency about recruiting so we can see the odds of them meeting the timeline.
- Wed Dec 30, 2020 8:41 pm
- Forum: ImetelChat
- Topic: Dr. Bose on ASH
- Replies: 3
- Views: 2733
Re: Dr. Bose on ASH
From the video: "There is no new data here"
- Wed Dec 30, 2020 8:31 pm
- Forum: ImetelChat
- Topic: Just for fun... and happier hope
- Replies: 2
- Views: 2672
Re: Just for fun... and happier hope
Many cancer cures have been "found" (e.g. gene vectors to put in more copies of p53).
But only a REAL psychic can tell you when one will be APPROVED
Happy New Year, let's hope 2021 is less stupid than 2020.
But only a REAL psychic can tell you when one will be APPROVED
Happy New Year, let's hope 2021 is less stupid than 2020.
- Mon Dec 21, 2020 7:11 pm
- Forum: ImetelChat
- Topic: Where's Waldo?
- Replies: 3
- Views: 2999
Re: Where's Waldo?
> if you could look into my mind you would see something more akin to a lava lamp
Yes, that's the inevitable result of listening to four or more Calls Of Chipthulhu.
Yes, that's the inevitable result of listening to four or more Calls Of Chipthulhu.
- Wed Dec 09, 2020 8:16 pm
- Forum: ImetelChat
- Topic: A view by a patient and investor
- Replies: 3
- Views: 2381
Re: A view by a patient and investor
Best of luck to you karagozoglu12345 with your transplant process.
Be careful about catching anything while you're immune-suppressed, of course. Take your Vitamin D etc.
https://clinicaltrials.gov/ct2/show/NCT ... w=2&rank=2
Be careful about catching anything while you're immune-suppressed, of course. Take your Vitamin D etc.
https://clinicaltrials.gov/ct2/show/NCT ... w=2&rank=2
- Thu Dec 03, 2020 4:01 pm
- Forum: ImetelChat
- Topic: Luspatercept moves into MF field
- Replies: 0
- Views: 2005
- Mon Nov 30, 2020 8:47 pm
- Forum: ImetelChat
- Topic: The Scarlett Letter
- Replies: 3
- Views: 2521
Re: The Scarlett Letter
Don't forget the recent large dilution at $1.30, and the fact that Scarlett is sitting on yet another ATM issue. If Geron had some good news (e.g., finally completing enrollment of a trial), Scarlett stands ready to crush the stock price yet again. The market has been burned by Geron dozens of times...
- Fri Oct 23, 2020 5:42 pm
- Forum: ImetelChat
- Topic: Full text link to review paper on MPNs
- Replies: 0
- Views: 2535
Full text link to review paper on MPNs
https://sci-hub.st/10.1080/17474086.2020.1831381
Paper stresses the need for a full-length Phase 3 on imetelstat, says that presently patients' main hope is stem cell transplant. Still, at least imet is on the radar.
Paper stresses the need for a full-length Phase 3 on imetelstat, says that presently patients' main hope is stem cell transplant. Still, at least imet is on the radar.
- Fri Oct 16, 2020 4:52 pm
- Forum: ImetelChat
- Topic: Trying to connect dots that may or may not exist and if they do, they move like the three body problem
- Replies: 5
- Views: 3626
Re: Trying to connect dots that may or may not exist and if they do, they move like the three body problem
There are at least four other drugs under consideration or awarded orphan status for myelofibrosis in the EU, including luspatercept: https://www.ema.europa.eu/en/search/search/field_ema_web_categories%253Aname_field/Human/ema_group_types/ema_orphan/field_ema_orp_disease_condition%253Aname_field/Tre...
- Sun Oct 04, 2020 4:20 pm
- Forum: ImetelChat
- Topic: Why would GERN need $75M facility?
- Replies: 5
- Views: 4813
Re: Why would GERN need $75M facility?
I think it's clear cut... they haven't been able to recruit enough patients for the trials, and they're behind schedule. They're just making sure that they can cross the finish line on one trial before running out of money.
And it's not $75 million UNLESS they hit their milestones.
And it's not $75 million UNLESS they hit their milestones.
- Tue Sep 22, 2020 3:53 pm
- Forum: ImetelChat
- Topic: CD 47 continued again
- Replies: 2
- Views: 2836
Re: CD 47 continued again
There was nothing "strange" about the volume on Friday, it was index rebalancing plus a little option expiration.
You've seen this a dozen times before, just look it up.
You've seen this a dozen times before, just look it up.
- Wed Sep 16, 2020 10:55 pm
- Forum: ImetelChat
- Topic: Forty Seven
- Replies: 1
- Views: 2132
Re: Forty Seven
Yes, this is an important result. I posted about FortySeven last year, now they have GILD backing too. While they aren't starting out aiming at low risk MDS, this could limit Geron's expansion into AML... although it's always possible that the most effective genetic targets are different, or even th...
- Mon Sep 14, 2020 8:19 pm
- Forum: ImetelChat
- Topic: Wainright Presentation
- Replies: 1
- Views: 2126
Re: Wainright Presentation
I'm sure Geron will get into ASH. Even if the trial results were negative, they're still human trial results on a new MOA, so are important either way.
- Mon Sep 14, 2020 8:18 pm
- Forum: ImetelChat
- Topic: Hoosier Investor please comment
- Replies: 5
- Views: 3923
Re: Hoosier Investor please comment
@Ryan: not only did I not "knock" Geron's preclinicals... I DID the first preclinicals on imetelstat while I was at Shay-Wright lab :roll: And I lost a bundle when JNJ and Scarlett tricked us into believing that JNJ was going to continue (the "job posting", the compassionate-use listing, and all the...
- Mon Sep 14, 2020 8:11 pm
- Forum: ImetelChat
- Topic: Hoosier Investor please comment
- Replies: 5
- Views: 3923
Re: Hoosier Investor please comment
Thanks for looking at the patents, HI. I agree that Geron's "concept patent" (something that is not supposed to exist) on "telomerase inhibitors in MF, MDS, and AML" (I know it's three blood cancers, hope I remember the AML correctly?) does apply. The other patents mention "modified Guanines" and in...
- Fri Sep 04, 2020 6:40 pm
- Forum: ImetelChat
- Topic: Here’s the relevant patent hat tip to Cheng Ho and Robespierre
- Replies: 2
- Views: 2120
Re: Here’s the relevant patent hat tip to Cheng Ho and Robespierre
The patent on "any telomerase inhibitor in MF, MDS, and AML" should apply as well.
- Fri Sep 04, 2020 6:39 pm
- Forum: ImetelChat
- Topic: Orphan being discussed AML/MDS/JMML
- Replies: 9
- Views: 5540
Re: Orphan being discussed AML/MDS/JMML
What they're discussing is waiving the pediatric testing requirement, as you'll remember was done for the Phase 2.
This is a very good thing, it will speed up the trial... and as biopearl points out, incidence in children is super rare.
This is a very good thing, it will speed up the trial... and as biopearl points out, incidence in children is super rare.
- Tue Sep 01, 2020 9:00 pm
- Forum: ImetelChat
- Topic: New telomerase-inhibitor company MAIA has new paper
- Replies: 0
- Views: 2296
New telomerase-inhibitor company MAIA has new paper
Paper on MAIA's telomerase-inhibitor drug 6-thiodG coming out this month:
https://www.businesswire.com/news/home/ ... ncouraging
https://www.businesswire.com/news/home/ ... ncouraging