Search found 1665 matches
- Thu Jan 11, 2024 3:24 pm
- Forum: ImetelChat
- Topic: 50 New Positions Posted Today.........
- Replies: 11
- Views: 4241
Re: 50 New Positions Posted Today.........
Kmall, agree. Geron could support this sales force for 5 years with just the extra burden imposed by the FDA delay.
- Tue Jan 09, 2024 3:38 pm
- Forum: ImetelChat
- Topic: ICER - Institute for Clinical and Economic Review
- Replies: 5
- Views: 1212
Re: ICER - Institute for Clinical and Economic Review
Thanks for the background, pretty impressive advisory board. Will be interesting to see what their analysis reveals. It appears as a non profit, that they could be self appointed watch dogs to reign in or at least shine a spotlight on excessive medical costs. We really don’t know how Imetelstat will...
- Tue Jan 09, 2024 2:27 pm
- Forum: ImetelChat
- Topic: ICER - Institute for Clinical and Economic Review
- Replies: 5
- Views: 1212
Re: ICER - Institute for Clinical and Economic Review
Ryan, thanks for posting. Can you give us a primer on who ICER is and would would have commissioned this review (Geron, FDA, Pharmas?). thanks, bp
- Tue Jan 09, 2024 3:04 am
- Forum: ImetelChat
- Topic: 50 New Positions Posted Today.........
- Replies: 11
- Views: 4241
Re: 50 New Positions Posted Today.........
Wow, that’s a lot of positions. I think these positions are basically for “drug reps” who will call on doctors, hospitals and pharmacists. There are 50 of them. One person can not cover an entire state or other widely defined geography, especially if “50%” of the time they are traveling. Geron is bu...
- Sun Jan 07, 2024 6:12 pm
- Forum: ImetelChat
- Topic: Off-Topic - GERN stock
- Replies: 4
- Views: 1519
Re: Off-Topic - GERN stock
Geron has added (at expense) many layers of experts including those who specialize in being sure all the FDA t’s are crossed and i’s dotted. MA should be highly likely bolstered by virtually every expert we have heard who makes a point of emphasizing that the grade 3 and 4 cytopenias are actually “o...
- Sat Jan 06, 2024 10:22 pm
- Forum: ImetelChat
- Topic: 3 days ago
- Replies: 1
- Views: 815
Re: 3 days ago
Thanks RC. Good presentation with Imet highlights. What is striking to me is the willingness to offer BMT even to prolong life for a few months. An effective treatment agent is what they want especially one that modifies disease. For those who are “concerned/critical” of Imetelstats adverse effects,...
- Fri Dec 29, 2023 7:45 pm
- Forum: ImetelChat
- Topic: A few thoughts for the end of the old year and the beginning of the new
- Replies: 5
- Views: 2163
Re: A few thoughts for the end of the old year and the beginning of the new
MG, nice! Thanks for sharing and best wishes for the New Year.
- Thu Dec 28, 2023 7:19 pm
- Forum: ImetelChat
- Topic: A few thoughts for the end of the old year and the beginning of the new
- Replies: 5
- Views: 2163
A few thoughts for the end of the old year and the beginning of the new
2024 should be quite the year for us. Despite recent poorly researched hit articles (be careful where you get your advice, especially here!), 2024 should reveal new AML data, a window into the oral agent development and of course FDA approval. A few recent comments from the experts bear emphasis. I ...
- Thu Dec 28, 2023 12:11 am
- Forum: ImetelChat
- Topic: Thank you AGAIN Kaz, YMB
- Replies: 2
- Views: 1196
Re: Thank you AGAIN Kaz, YMB
RC either we are missing something or the FDA is. You know who gets my vote.
- Wed Dec 27, 2023 7:45 pm
- Forum: ImetelChat
- Topic: Audentes Fortuna Luvat
- Replies: 0
- Views: 1221
Audentes Fortuna Luvat
Nice shout out to Geron from Dr Zeidan for persistence in the face of Janssen hissy fit.
- Wed Dec 27, 2023 5:04 pm
- Forum: ImetelChat
- Topic: Thank you AGAIN Kaz, YMB
- Replies: 2
- Views: 1196
Thank you AGAIN Kaz, YMB
youtu.be/EeqbocpDmGI?si=YiL6A9aQOM6ye-Ce
- Tue Dec 26, 2023 1:24 am
- Forum: ImetelChat
- Topic: this might be interesting
- Replies: 1
- Views: 935
- Tue Dec 26, 2023 12:53 am
- Forum: ImetelChat
- Topic: Putting 6-thio-Dg into perspective
- Replies: 15
- Views: 14411
Re: Putting 6-thio-Dg into perspective
CKTC, I was hoping this patent might get your attention. Thanks for sharing your thoughts. I can’t imagine Geron would just roll on this without attempting some agreement on royalties (or merger—time to come home Sergei?) Happy holidays to all. bp
- Mon Dec 25, 2023 4:07 pm
- Forum: ImetelChat
- Topic: Putting 6-thio-Dg into perspective
- Replies: 15
- Views: 14411
- Fri Dec 22, 2023 4:56 am
- Forum: ImetelChat
- Topic: Kaz yet again keep them coming
- Replies: 2
- Views: 1183
Re: Kaz yet again keep them coming
RC, yes, this one is worth a careful listen even though it is very short. Points made: that Lus doesn’t seem to promote the malignant clone was viewed as good news. But no statement as to whether Lus suppresses the malignant clone. Dr. Brenner foresees the day when early disease can be detected and ...
- Fri Dec 22, 2023 4:39 am
- Forum: ImetelChat
- Topic: 2023 - What a Long, Strange Trip it’s Been
- Replies: 3
- Views: 2762
Re: 2023 - What a Long, Strange Trip it’s Been
HI and Ryan, I agree. Highly doubtful we will see Imet 2.0 before the end of the year. Another over promise and under deliver, Yes, John, you did say by the end of the year. I have to wonder (again) if the envelope between the intentional and unintentional is breached with intent or just irrational ...
- Thu Dec 21, 2023 11:01 am
- Forum: ImetelChat
- Topic: Kaz yet again keep them coming
- Replies: 2
- Views: 1183
Kaz yet again keep them coming
Many thanks:
youtu.be/Dlv2jcS3bQ4?si=CtmFzwLzsuX41n5Y
https://m.youtube.com/watch?si=CtmFzwLz ... e=youtu.be
youtu.be/Dlv2jcS3bQ4?si=CtmFzwLzsuX41n5Y
https://m.youtube.com/watch?si=CtmFzwLz ... e=youtu.be
- Wed Dec 20, 2023 6:20 pm
- Forum: ImetelChat
- Topic: CKTC
- Replies: 2
- Views: 2900
CKTC
Been thinking about your last post. Here’ MAIA with an “elegant” drug with advantages at least in theory over Imetelstat and significant human assets like Sergei M. Gryaznov and Jerry Shay both of whom were once part of Geron. And yet… And yet, they seem to be way behind in clinical development and ...
- Wed Dec 20, 2023 5:14 pm
- Forum: ImetelChat
- Topic: Putting 6-thio-Dg into perspective
- Replies: 15
- Views: 14411
Re: Putting 6-thio-Dg into perspective
CKTC, thanks as always for posting. I do wonder if the lag time for Imetelstat is much less of an issue with AML since the cell doubling time is measured in hours. Also the “non canonical” effects of Imetelstat, now known to be related to ferroptosis effects might be at play. Of course the subtext o...
- Sun Dec 17, 2023 6:16 pm
- Forum: ImetelChat
- Topic: Hat tip again to Kaz YMB
- Replies: 1
- Views: 4740
Hat tip again to Kaz YMB
https://www.youtube.com/watch?v=EfI-CqCMubw https://www.youtube.com/watch?v=EfI-CqCMubw Rami says ADCOM in April Other salient feature, Grade 3-4 neutropenia in 68 % (manageable and transient) but notably only 1% with febrile neutropenia. It’s a stretch and a guess but regarding the need for hospita...