ImetelChat

Wow, you are amazing Fishermangents! It is impressive that you can pull so much information together from so many sources and put it into something coherent that a person like myself can comprehend. Thank you again for your thoughts and efforts here and doing the heavy lifting on this board. So it w...

As we continue to learn about the development process / progress on ImetelChat that Geron is struggling through with it’s j”transformative” drug Imetelstat and our own personal difficulties trying to procure the drug as life slipped away, I think and hope there must be more that could be done here. ...

Okay, thanks again for your perspective as it certainly reflects our experience regarding accessibility to the drug outside of a CT. ODD should be considered primarily beneficial to the businesses involved and possibly those participating in related CTs. Others with the disease and not fitting the C...

Thanks Fishermangents for your reply and always very good thoughts, all of which reflect and educate us on the challenges faced by the principals. I would reflect that given we on the outside recognize the awesome capabilities and potential of Imetelstat, how much more might they on the inside know ...

Orphan drug designation I’m sorry about this being so long, edit as necessary if you keep it up. It has been a weighty subject for me for a long time and I suspect many suffering with the diseases of MF and MDS as well. What does ODD really mean and why haven’t we seen more attention on this aspect ...

Okay, thank you. Just wasn't looking in the right places or maybe just not paying attention. Interesting reading on the use of these drugs, dosing, combinations, cycles, etc. You probably have seen this but found this interesting: http://www.myelomabeacon.com/news/2014/04/02/revlimid-velcade-dexamet...

Was wondering if anyone had listened to the Charlie Rose (Bloomberg) interview of Tom Brokaw (NBC News) last night (5-17-16)? I think he said he suffered from Multiple Myeloma beginning late 2013 and was diagnosed at the Mayo Clinic? Based on his comments, I was wondering what treatment was responsi...

Okay, thanks. Will check out the article but will probably find it too technical as well.

Thanks Fishermangents for the information and I assume your comments following the three points on the AACR poster presentations. Not being very knowledgeable on the science at this level, I was wondering if you could elaborate on what the on-target mechanisms of Imetelstat are that affect the plate...

I saw a post regarding this web blog today in the Geron YMB, Didn't think there was any news in this info regarding using Imetelstat for AML but maybe I'm missing something. So much going on with Imetelstat in & outside of the US but nothing official on an AML clinical trial, but suspect we are gett...