Search found 1665 matches

by biopearl123
Fri Aug 18, 2023 11:45 pm
Forum: ImetelChat
Topic: By my count, day 60 is Saturday
Replies: 23
Views: 11534

Re: By my count, day 60 is Saturday

Expletive allowed, especially under the circumstances.
by biopearl123
Fri Aug 18, 2023 10:34 pm
Forum: ImetelChat
Topic: By my count, day 60 is Saturday
Replies: 23
Views: 11534

Re: By my count, day 60 is Saturday

KT, first off thanks for your kind words it been really fun and interesting for me to have so many thoughtful posters such as yourself. I think the time line goes like this. No time served. Clock for review starts with acceptance of NDA, 6 months for priority review and ten for standard. Whether rol...
by biopearl123
Fri Aug 18, 2023 8:23 pm
Forum: ImetelChat
Topic: By my count, day 60 is Saturday
Replies: 23
Views: 11534

Re: By my count, day 60 is Saturday

Thanks Gwik! LWS, as to your comments. Geron has been very straightforward in guiding their intention to file, and when confirming when they actually did file, so it seems that they have committed themselves to us to provide the ultimate status of the NDA at day 60. That takes care of your options 1...
by biopearl123
Fri Aug 18, 2023 5:15 pm
Forum: ImetelChat
Topic: By my count, day 60 is Saturday
Replies: 23
Views: 11534

Re: By my count, day 60 is Saturday

Earfool, thanks for the kind words. I honestly think Geron goes about their business (hiring) while waiting for the FDA to go about theirs. They can’t say much during the FDA vetting process. They can’t buy or sell stock themselves since they are in possession of “inside” info. I find it a little re...
by biopearl123
Fri Aug 18, 2023 1:41 pm
Forum: ImetelChat
Topic: By my count, day 60 is Saturday
Replies: 23
Views: 11534

Re: By my count, day 60 is Saturday

Thank you bucbeard. Much appreciated.
by biopearl123
Fri Aug 18, 2023 3:24 am
Forum: ImetelChat
Topic: By my count, day 60 is Saturday
Replies: 23
Views: 11534

Re: By my count, day 60 is Saturday

I know the kind of friend you were to Matt. Had one myself once before he drank himself to death. It’s a once in a lifetime thing only a few can understand. But you do. Hands across the water. Best wishes old friend.
by biopearl123
Fri Aug 18, 2023 3:19 am
Forum: ImetelChat
Topic: I'm induced
Replies: 3
Views: 2491

Re: I'm induced

You made me laugh yet again.
by biopearl123
Fri Aug 18, 2023 3:17 am
Forum: ImetelChat
Topic: By my count, day 60 is Saturday
Replies: 23
Views: 11534

Re: By my count, day 60 is Saturday

Hasn’t it though? Thank you kmall, most kind. You have been the best sidekick a buckaroo could ask for. Ryan pointed out that the PR for NDA filing was actually a 6 am event suggesting the actual filing was June 19 so maybe tomorrow???
by biopearl123
Fri Aug 18, 2023 1:14 am
Forum: ImetelChat
Topic: By my count, day 60 is Saturday
Replies: 23
Views: 11534

By my count, day 60 is Saturday

Best wishes and good luck to all. I look forward to the day when I can sign off, knowing I kept my promise to a dying man I never met and to his son. bp
by biopearl123
Wed Aug 16, 2023 2:37 am
Forum: ImetelChat
Topic: Biogen buys Reata for $7.3B.....
Replies: 3
Views: 2402

Re: Biogen buys Reata for $7.3B.....

So much goes on behind the scenes. We can only wonder what John has been up to. Reata projecting 1.5 B sales in 2030. Geron 7B in 2033.
by biopearl123
Tue Aug 15, 2023 5:59 pm
Forum: ImetelChat
Topic: Hat tip to Luis Alberto, YMB
Replies: 2
Views: 1762

Re: Hat tip to Luis Alberto, YMB

I’m with you, “pretty pretty good”. Hat tip to Larry David.
by biopearl123
Sat Aug 12, 2023 9:42 pm
Forum: ImetelChat
Topic: More on the role of inflammation
Replies: 2
Views: 1936

Re: More on the role of inflammation

Yes. Inflammation in cancer is very important and may impact other causes of morbidity and mortality. Understanding the role of implantation better may lead to different combination approaches and also provide predictive value.
by biopearl123
Sat Aug 12, 2023 5:06 pm
Forum: ImetelChat
Topic: It appears that I have been banned from YMB
Replies: 1
Views: 1020

It appears that I have been banned from YMB

Interesting. I wonder what they are afraid I would say?
by biopearl123
Sat Aug 12, 2023 12:25 am
Forum: ImetelChat
Topic: NDA submitted
Replies: 22
Views: 13292

Re: NDA submitted

I wonder if by taking its time to review the NDA now, Geron will be given a shorter PUDUFA date. In theory, since the application was granted rolling review, each module has already been closely examined by the FDA over an extended period of time with the possible exclusion of the last submitted mod...
by biopearl123
Sun Aug 06, 2023 9:49 pm
Forum: ImetelChat
Topic: If you are feeling anxious about the future of Imetelstat in LR MDS…
Replies: 5
Views: 2284

Re: If you are feeling anxious about the future of Imetelstat in LR MDS…

Kmall, wellllll, I have no counter argument to your points. Not a one. This all should have happened a looong time ago. A long (insert word) time ago. “Fast track” is laughably euphemistic.
by biopearl123
Sun Aug 06, 2023 7:41 am
Forum: ImetelChat
Topic: If you are feeling anxious about the future of Imetelstat in LR MDS…
Replies: 5
Views: 2284

If you are feeling anxious about the future of Imetelstat in LR MDS…

As we approach the NDA acceptance date, if you are feeling a little anxious, ask your self the following: 1. Are you aware of any agent in development or in the clinic that has shown conclusive disease modification in this condition. Answer: Yes you are. 2. Are you aware of any agent in development ...
by biopearl123
Sun Aug 06, 2023 12:23 am
Forum: ImetelChat
Topic: My G-d this is frustrating
Replies: 3
Views: 2531

Re: My G-d this is frustrating

No sh-t.
by biopearl123
Fri Aug 04, 2023 8:39 pm
Forum: ImetelChat
Topic: Hat tip to Fern64 from stocktwits
Replies: 1
Views: 1265

Hat tip to Fern64 from stocktwits

https://www.onclive.com/view/imetelstat-for-lower-risk-mds-data-from-the-imerge-trial Very nice 10 min discussion. Worth listening all the way to the end for clarity on the “extension” study (QT study) which was a back door in for patients who had also also received HMA’s. The QT part of the study (...