Search found 353 matches
- Mon Dec 11, 2023 9:04 pm
- Forum: ImetelChat
- Topic: Adverse effects
- Replies: 8
- Views: 11384
Re: Adverse effects
True. Bluebird’s box warning was related to the risk of emergence of rare cancers. Fortunately, the grade 3 and 4 events with Imetelstat were not and appear to be reversible. Again agree. “Adverse effects” are in different leagues, however Geron seemingly will need to put in effort to avoid any war...
- Mon Dec 11, 2023 5:05 pm
- Forum: ImetelChat
- Topic: Adverse effects
- Replies: 8
- Views: 11384
Re: Adverse effects
True, good point.
Tangentially, Bluebird treatment got slapped with a box Warning. To state the obvious, Not looked on positively.
Tangentially, Bluebird treatment got slapped with a box Warning. To state the obvious, Not looked on positively.
- Sun Dec 10, 2023 8:58 pm
- Forum: ImetelChat
- Topic: ASH - twitter
- Replies: 10
- Views: 12924
Re: ASH - twitter
Nice, extended follow-ups and breakout of subgroup (using IPSS, prognostic scoring system).
Let’s see if this Phase III extended data leads to a Plenary…
Let’s see if this Phase III extended data leads to a Plenary…
- Thu Dec 07, 2023 7:31 pm
- Forum: ImetelChat
- Topic: An open inquiry..
- Replies: 5
- Views: 6973
Re: An open inquiry..
I think it’s sooner rather than later biotechs are going to implement AI to find potential optimizations to their drugs (molecules) as well as analyzing combinations , etc etc etc…. Probably another reason why the global giants have a huge advantage with their IP. I would gather that company announc...
- Tue Dec 05, 2023 8:23 pm
- Forum: ImetelChat
- Topic: Dr. Patnaik, editorial comment in Lancet
- Replies: 10
- Views: 17803
Re: Dr. Patnaik, editorial comment in Lance
Like every major featured article in a top tier medical journal, a prominent physician is asked to comment. I did "buy" 24 hour access to the comments by Dr. Patnaik of the Mayo in Rochester. I am sure I had to agree not to reproduce it so I will just summarize a few points. Dr. Patnaik summarized ...
- Mon Dec 04, 2023 9:44 pm
- Forum: ImetelChat
- Topic: things have a way of coming full circle
- Replies: 6
- Views: 8836
Re: things have a way of coming full circle
Ryan, I did not mean to cast doubt on your ability or anyone else’s to appreciate the current presentation of the Imetelstat data. I was merely sharing my own reaction to my first subscription to the NEJM as a first year, first day 22 year old medical student. No aspersions or judgements were meant...
- Mon Dec 04, 2023 5:12 pm
- Forum: ImetelChat
- Topic: things have a way of coming full circle
- Replies: 6
- Views: 8836
Re: things have a way of coming full circle
The commentary that accompanies the Lancet article: https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(23)02187-6/fulltext# takes us back to the Mayo Clinic in Rochester Minn. I hope Dr. Tefferi is able to find some satisfaction in seeing a close colleague of his bring further recognit...
- Sun Dec 03, 2023 11:58 pm
- Forum: ImetelChat
- Topic: twitter
- Replies: 11
- Views: 13798
Re: twitter
And the best response of all;) !
When the data is so amazing, but of course very difficult to comprehend on a basic (normal people like us) level, just post a “:)”
- Sun Dec 03, 2023 11:56 pm
- Forum: ImetelChat
- Topic: twitter
- Replies: 11
- Views: 13798
Re: twitter
“Ready for Prime Time”
There it is, the overnight success story that was 12 years in the making.
- Sun Dec 03, 2023 11:54 pm
- Forum: ImetelChat
- Topic: twitter
- Replies: 11
- Views: 13798
Re: twitter
Nice, ‘#MDS Gurus from around the world’ pretty much says it all
(Quoted the wrong tweet, it was Dr. Madanat’s tweet that says this.)
- Fri Dec 01, 2023 11:50 pm
- Forum: ImetelChat
- Topic: 2 year anniversary.......
- Replies: 2
- Views: 4048
Re: 2 year anniversary.......
Ouch. Getting roasted.
Wonder if that’s worth over a million in salary and options in that time
He still has time to come through!
Wonder if that’s worth over a million in salary and options in that time
He still has time to come through!
- Mon Nov 20, 2023 5:27 pm
- Forum: ImetelChat
- Topic: Top Geron Clinician Goes To Vividion Therapeutics.....
- Replies: 29
- Views: 55593
Re: Top Geron Clinician Goes To Vividion Therapeutics.....
The Gong didn’t work :roll: I like seeing the background of new hires. Not sure I’m too worried about someone who has probably become Dr Rizo’s friend / confidant over the years. As refernced, ai further that an exodus of science experts (not worried about the CLO or CFO) from the company. Noting th...
- Fri Nov 17, 2023 9:49 pm
- Forum: ImetelChat
- Topic: Priority Review
- Replies: 5
- Views: 4645
Re: Priority Review
So no one is buying into the New Molecular Entity thing I see.
Me neither.
Me neither.
- Wed Nov 15, 2023 8:06 pm
- Forum: ImetelChat
- Topic: Today the EMA Approves Modification to Imetelstat PIP
- Replies: 23
- Views: 14223
Re: Today the EMA Approves Modification to Imetelstat PIP
I would say that every time there is a modification to this trial, a lot of flags are raised and flown, a lot of cheers and exuberance… but, I agree that this is a non-issue. It’s been stated that this is part and parcel with an application for marketing approval with the EMA. If a new trial were be...
- Sun Nov 12, 2023 7:16 pm
- Forum: ImetelChat
- Topic: Another feather in the cap........
- Replies: 4
- Views: 2936
Re: Another feather in the cap........
Such valid conjecture there.
From the data, I would be absolutely stunned/shocked absolutely flummoxed, choose your word… if Imetelstat is not approved for marketing authorization by the FDA…
— But from the vibes and the Geron share price, I wouldn’t be surprised in the least <— go figure.
From the data, I would be absolutely stunned/shocked absolutely flummoxed, choose your word… if Imetelstat is not approved for marketing authorization by the FDA…
— But from the vibes and the Geron share price, I wouldn’t be surprised in the least <— go figure.
- Sun Nov 12, 2023 7:13 pm
- Forum: ImetelChat
- Topic: on australian news
- Replies: 5
- Views: 3232
Re: on australian news
Notice this is not Geron PR involved in this press, articles and news clips, in Australia. Dr. Lane and Dr. Claudia B are independently interacting with journalists, who find their discoveries news worthy. That is their right as industry experts, but it is clear Geron is not involved in this ‘public...
- Thu Nov 09, 2023 12:03 am
- Forum: ImetelChat
- Topic: Claudia has been chasing this chimera for a long time and deserves a whole lot of credit
- Replies: 2
- Views: 1984
Re: Claudia has been chasing this chimera for a long time and deserves a whole lot of credit
So true. Her quote from the article I posted (“Dr Lane speaks”) definitely shows her excitement about reaching this point in what clearly was/is a long and winding road: Lead author Dr Claudia Bruedigam from QIMR Berghofer said the research involved years of tireless work by an international researc...
- Tue Nov 07, 2023 3:53 pm
- Forum: ImetelChat
- Topic: $382 Million
- Replies: 7
- Views: 6529
Re: $382 Million
Share price is controlled by buyers and sellers. There is no entity or entities “controlling” the stock price behind the proverbial curtain. Take notice that the management times every, single private share offering or intent to offer… with good news.
No need to respond LWS. Please don’t.
No need to respond LWS. Please don’t.
- Sun Nov 05, 2023 7:36 pm
- Forum: ImetelChat
- Topic: $382 Million
- Replies: 7
- Views: 6529
Re: $382 Million
Well you were incorrect about the current funds, however, have been pretty right about the clear disdain for individual shareholders by management. Once again, they drop a stink bomb on what otherwise would have been catalyst-creating amazing news. The agreement for $100M at the market authorized sh...
- Sat Nov 04, 2023 3:46 pm
- Forum: ImetelChat
- Topic: Professor Lane speaks
- Replies: 0
- Views: 6541
Professor Lane speaks
“Having this extra weapon in our arsenal would create so much opportunity particularly in combining this drug, and others like it, with existing treatments like chemotherapy and other novel cancer therapies," Professor Lane said. "This could transform the way we think about treating patients with bl...