Search found 1665 matches

by biopearl123
Wed Apr 12, 2023 4:27 pm
Forum: ImetelChat
Topic: Incyte's "Purple Chair" commercial for JAKafi........
Replies: 2
Views: 748

Re: Incyte's "Purple Chair" commercial for JAKafi........

Well done and poignant. Real patients and a series that might actually give other new patients some help and guidance. I hope Geron can build on this.
by biopearl123
Tue Apr 11, 2023 4:50 pm
Forum: ImetelChat
Topic: increase shares proposal
Replies: 28
Views: 10336

Re: increase shares proposal

Zhears, I suspect you are right. The timing of the meeting and the extremity of the “ask”, suggests that they want to maximize the likelihood of some positive antecedent event that will garner support for what is as of now a very ill defined need for the approval for more shares.
by biopearl123
Mon Apr 10, 2023 9:39 pm
Forum: ImetelChat
Topic: Senior Director, Global Pricing and Contracting - another JNJ alum.....
Replies: 11
Views: 2698

Re: Senior Director, Global Pricing and Contracting - another JNJ alum.....

Good points all around, good enough that I won’t bet a dollar on it.
by biopearl123
Mon Apr 10, 2023 8:05 pm
Forum: ImetelChat
Topic: Senior Director, Global Pricing and Contracting - another JNJ alum.....
Replies: 11
Views: 2698

Re: Senior Director, Global Pricing and Contracting - another JNJ alum.....

Bucbeard, J and J had 153,000 employees (!!). I am guessing there is plenty of redundancy regarding positions of this nature, doubt they feel the attrition. Kmall has helped us understand whether these folks are leaving J and J for greener pastures, e.g. Geron or whether they represent an “advance t...
by biopearl123
Sun Apr 09, 2023 5:26 pm
Forum: ImetelChat
Topic: You've got to be kidding me........
Replies: 10
Views: 3291

Re: You've got to be kidding me........

LWS you are on notice and I will ban you. Don’t push your luck
by biopearl123
Sun Apr 09, 2023 4:33 am
Forum: ImetelChat
Topic: You've got to be kidding me........
Replies: 10
Views: 3291

Re: You've got to be kidding me........

I think there is no issue regarding the FDA’s independence regarding approval (or not) of Imetelstat. The glacial speed of evaluation for approval speaks for itself. I think these points have been made and emphasized at this point.
by biopearl123
Sun Apr 09, 2023 1:39 am
Forum: ImetelChat
Topic: Imetelstat Displays Early Efficacy in Myelofibrosis; Phase 3 Trial Is Underway
Replies: 1
Views: 938

Re: Imetelstat Displays Early Efficacy in Myelofibrosis; Phase 3 Trial Is Underway

Ryan, thanks for posting this. Dr. M continues to emphasize that Imetelstat is one of the few (?only) treatments in the “clinic or in development” that targets the cancer stem cell and the malignant clone. That has always been a touchstone for me. Be so interesting to see if combination therapy affe...
by biopearl123
Sun Apr 09, 2023 12:17 am
Forum: ImetelChat
Topic: You've got to be kidding me........
Replies: 10
Views: 3291

Re: You've got to be kidding me........

OK,OK this thread has gotten way off of our mission here. This is one of the very rare times I will use the red pen. I will let the discussion stand for a few hours and then delete the parts that are irrelevant to Geron and Imetelstat and the topic of cancer treatments in general. Don’t take it pers...
by biopearl123
Thu Apr 06, 2023 4:40 pm
Forum: ImetelChat
Topic: increase shares proposal
Replies: 28
Views: 10336

Re: increase shares proposal

Kmall, when I first said it, I confess that tongue was inserted firmly in cheek. But after all, we have supported John and the Geron board from the moment he took over. I can’t remember one board proposal that was defeated by shareholder vote ever. So if ever there were a time to acknowledge the loy...
by biopearl123
Thu Apr 06, 2023 4:30 pm
Forum: ImetelChat
Topic: Specific question
Replies: 3
Views: 1408

Re: Specific question

Gwickley, Imetelstat was tested in multiple myeloma over a decade ago. Two institutions were involved, University of Maryland and Johns Hopkins. The study showed a reduction in the number of circulating myeloma stem cells. It did not rate an oral or poster presentation at a major meeting. As far as ...
by biopearl123
Wed Apr 05, 2023 11:56 pm
Forum: ImetelChat
Topic: increase shares proposal
Replies: 28
Views: 10336

Re: increase shares proposal

Bucbeard, only if those share find their way to the market. Then yes even managements share value is diluted. It’s about the threat. The sword remains sheathed. At least for now. As Sun Tzu said: “the strongest warrior never has to fight”. A poison pill kills everyone. Best not to take it.
by biopearl123
Wed Apr 05, 2023 8:27 pm
Forum: ImetelChat
Topic: increase shares proposal
Replies: 28
Views: 10336

Re: increase shares proposal

Maybe that’s because Dr. Scarlett wants to give his long suffering shareholders a special stock dividend?
by biopearl123
Wed Apr 05, 2023 12:43 am
Forum: ImetelChat
Topic: And another job down
Replies: 1
Views: 800

And another job down

Two left up on positions site.
by biopearl123
Mon Apr 03, 2023 5:47 am
Forum: ImetelChat
Topic: You've got to be kidding me........
Replies: 10
Views: 3291

Re: You've got to be kidding me........

You knew!
by biopearl123
Mon Apr 03, 2023 3:55 am
Forum: ImetelChat
Topic: You've got to be kidding me........
Replies: 10
Views: 3291

Re: You've got to be kidding me........

I bet you $1.00 the April/May miracle makes you change your mind. 😊
by biopearl123
Sun Apr 02, 2023 8:17 pm
Forum: ImetelChat
Topic: You've got to be kidding me........
Replies: 10
Views: 3291

Re: You've got to be kidding me........

Well you can’t deny that she has experience and maybe learned some hard lessons from it.
by biopearl123
Sat Apr 01, 2023 4:24 am
Forum: ImetelChat
Topic: increase shares proposal
Replies: 28
Views: 10336

Re: increase shares proposal

Ryan, perhaps you would like to lead the discussion as to how a poison pill might work as it pertains to Geron and how that might protect share holder value. If this is part of a poison pill strategy, Geron must be concerned about a potential hostile takeover.
by biopearl123
Sat Apr 01, 2023 1:09 am
Forum: ImetelChat
Topic: increase shares proposal
Replies: 28
Views: 10336

Re: increase shares proposal

HI, was waiting for your take on this. Either they think someone is going to want a whole of shares e.g. a partner or couldn’t this be a poison pill strategy to prevent a hostile take over? Admittedly my understanding of this is limited and an expanded discussion of what they could possibly be think...
by biopearl123
Sat Apr 01, 2023 12:07 am
Forum: ImetelChat
Topic: increase shares proposal
Replies: 28
Views: 10336

Re: increase shares proposal

I nominate Dr. Samuel Hahnemann to the board.