ImetelChat

Scarlett never addressed why JNJ was looking for a pricing manager for imetelstat for AML in addition to MDS and MF - that came out of nowhere - I would like to go to the shareholders meeting to ask him that question - was it a surprise to him or was he aware they were working on something? I am sur...

i think they bailed due to the italian paper on MOS - when it came out there was no chance to refute it or prove it and thus they didn't feel comfortable in committing up to a billion dollars to continue - that killed the deal - the FDA must think there is something here to grant fast track after lo...

i do not think he sold all but he did sell a large percentage

everyone got their stock options friday - a little later than years before - now they can let the price come up

if Imbark is approved, it is because they believe it is disease modifying - that would make it front line

brining this from seeking alpha - posted by Hoosier Investor - published a few days ago
https://www.cancernetwork.com/myeloprol ... lofibrosis

if Imbark is active against MF and not only covering symptoms it should not only be approved for those refractory to Jakafi - should be started with Jakafi or before - you dont wait until someone has one foot in the grave before starting a disease modifying compound I think they are going for AML li...

I agree about not addressing the cause - I always think about the May 4th Ct order and what it was regarding that was so unusual about the CRO plan
-could they go for AA for R/R and
-phase 3 for combo/ single agent study - cant see doing a placebo

they aren't going front line because the need is met - they are going after unmet needs because they wants AA and anything less would be a disappointment

Unmet need
- these patients have no hope - so if there ever was an indication for a phase 4 this would be it - maybe we can catch a break for once

i think a phase 3 approval is a no brainer - assumed this once the fast track was designated - was hoping for an early approval - this will decrease the stock price just in time for board members to get their stock options for the year

thanks for the link - hopefully we get some good news - I am expecting approval for a phase 3 but hoping for early approval

selling shares at such a low price does not give me the warm and fuzzies but I put a lot of stock in the people who left secure jobs to place their bet on GERN options - I have also been encouraged by this podcast http://www.managingmds.com/con-ed-mds/what’s-new-and-what’s-next-in-the-treatment-of-m...

i thought Scarlet said he would not be doing any result updates for the imerge trial

last year - they scheduled the third quarter results the day the ASH abstracts were announced - Nov1st - done at 430pm same day - this year they will issue a statement at 430pm and have a morning premarket meeting to update progress with Geron - they must have something positive to release outside o...

the abstracts are posted online at 9am EST Wed Nov 6th - odd they are doing the PC for recent happenings at 8am on thursday and releasing 3rd quarter results wednesday night

the phase 2 always said phase 2/3 and nobody could ever explain why - there were 55 patients in the phase 2/3 - 170 +55=225 and I think this was the plan all along to continue those patients from 2/3 into phase 3