Search found 367 matches
- Fri Jun 29, 2018 6:02 pm
- Forum: ImetelChat
- Topic: Clinical trial site update today MDS study
- Replies: 0
- Views: 3152
Clinical trial site update today MDS study
The Clinical trials site has been updated to reflect a 4 month extension of the anticipated conclusion of the MDS study. Since the extra 25 patients have completed enrollment in Feb I believe this extension signals a firm plan to proceed to part two of the phase III study. bp
- Thu Jun 28, 2018 10:23 pm
- Forum: ImetelChat
- Topic: So when does common sense and morality come into play?
- Replies: 1
- Views: 3042
Re: So when does common sense and morality come into play?
Nicely said Hunt, I think it is a good summary of the frustrations patients are feeling as they wait. And wait. Clearly the FDA was not willing to approve on the basis of the Dr. Tefferi studies or even the ET studies. In some ways waiting for a critical juncture is strategic-- the longer we wait th...
- Tue Jun 26, 2018 4:52 pm
- Forum: ImetelChat
- Topic: New Geron slide set on home page
- Replies: 2
- Views: 3063
Re: New Geron slide set on home page
Also note "exploratory" indications. This could mean anything. Solid tumors for example. bp
- Tue Jun 26, 2018 4:51 pm
- Forum: ImetelChat
- Topic: New Geron slide set on home page
- Replies: 2
- Views: 3063
Re: New Geron slide set on home page
The writing is on the wall for those who wish to read it. Toward the end of the presentation is a clear indication of future plans. ("if" continuation decision.) AML phase II/III, MF Phase III. MDS phase III. Re the reference to MF phase III: Scarlet has said that there are no plans within the rubri...
- Tue Jun 26, 2018 3:57 pm
- Forum: ImetelChat
- Topic: New Geron slide set on home page
- Replies: 2
- Views: 3063
- Mon Jun 25, 2018 8:14 pm
- Forum: ImetelChat
- Topic: Looking at EHA presentation a little more closely
- Replies: 4
- Views: 5788
Re: Looking at EHA presentation a little more closely
Ucj, it is my pleasure. I hope we can get an active vibrant board going. Greg, thank you for responding, if indeed we are looking at this correctly and I think we are, taken as a whole if only two patients did not respond at all and one patient got worse we are looking at over a 90% response rate. G...
- Sun Jun 24, 2018 8:59 pm
- Forum: ImetelChat
- Topic: Article ref form taz
- Replies: 1
- Views: 1992
Re: Article ref form taz
It appears that the MF pts in this study are not end stage advanced cases so results may not be comparable toJanssen study. The future possility of combinations remains intriguing bp
- Sun Jun 24, 2018 4:33 pm
- Forum: ImetelChat
- Topic: Article ref form taz
- Replies: 1
- Views: 1992
Article ref form taz
https://onlinelibrary.wiley.com/doi/ful ... /cam4.1619
Combo of rux and interferon with some remissions. Will do a close read and try to comment when I can but I thought I would at lease post the reference so folks can start reading and commenting. bp
Combo of rux and interferon with some remissions. Will do a close read and try to comment when I can but I thought I would at lease post the reference so folks can start reading and commenting. bp
- Sun Jun 24, 2018 1:24 am
- Forum: ImetelChat
- Topic: More on the EHA presentation re marrow recovery
- Replies: 2
- Views: 3070
Re: More on the EHA presentation re marrow recovery
I will look through my Dr.T notes but I think you are right. bp
- Sun Jun 24, 2018 1:22 am
- Forum: ImetelChat
- Topic: Sdraw epic thesis
- Replies: 1
- Views: 2063
Re: Sdraw epic thesis
Dogonenuts, Sdraw thoughts have been incredibly perspicacious. He did give permission for reposting (hint). Since the Imbark study collected data on the last patient on April 26th and since the FDA previously requested data from Janssen 6 or 7 months previously, I am thinking it’s possible the FDA a...
- Fri Jun 22, 2018 5:52 pm
- Forum: ImetelChat
- Topic: More on the EHA presentation re marrow recovery
- Replies: 2
- Views: 3070
More on the EHA presentation re marrow recovery
To my knowledge, CRs, PRs etc have not been previously described in MDS or MF, of this magnitude, is anyone aware of this occurring anywhere else? (I think Jakosa tried to make the case for JAKFI but I don't remember particulars and if anything there wasn't much of a comparison, correct me if I don'...
- Fri Jun 22, 2018 4:37 pm
- Forum: ImetelChat
- Topic: Looking at EHA presentation a little more closely
- Replies: 4
- Views: 5788
Looking at EHA presentation a little more closely
Good Day to all from your board moderator, biopearl. New members please don't forget to register or you can not post. Please do post and foster relevant discussions. Posts must be pertinent and avoid ad hominem attacks. A few thoughts on the EHA presentation. I have not actually heard the presentati...
- Mon Jun 18, 2018 7:13 pm
- Forum: ImetelChat
- Topic: Link to slides from EHA presentation
- Replies: 0
- Views: 2757
- Wed Jun 13, 2018 9:39 pm
- Forum: ImetelChat
- Topic: Goodbye
- Replies: 9
- Views: 13295
Re: Goodbye
Fish Jr., As you can see there are already many views on this site. You may not be aware that your Dad also posted on Seeking Alpha. I am including a link so you can see the comments made by those who will miss "Fish". I hope you have been able to read my notes to you and that we can move to a priva...
- Wed Jun 13, 2018 7:48 pm
- Forum: ImetelChat
- Topic: Goodbye
- Replies: 9
- Views: 13295
Re: Goodbye
Fish asked me to keep his medical condition confidential when he asked me to co moderate the Imetelchat board, and so I did. Now that his son "Fish Jr" has announced Fish's passing I think we can all extend to Fish's son our appreciation for the very high quality board his father established and fos...
- Wed Jun 13, 2018 3:18 pm
- Forum: ImetelChat
- Topic: To Fish Junior
- Replies: 0
- Views: 2797
To Fish Junior
Alex, First off you should know how greatly appreciated yours father's work on this board and his personal insights were valued by many. As to the future of this board, please know that I would like to communicate privately with you in this regard. The kind note you sent me had an invalid email addr...
- Fri Jun 08, 2018 10:11 pm
- Forum: ImetelChat
- Topic: Sdraw
- Replies: 3
- Views: 7479
Sdraw
Few posters has the scientific background or the willingness to educate that Sdraw does. I wish he would post here but I am unable to approve new posters even though I function as a moderator of sorts so instead I will for now be more of a triage agent and post links. Here is a link to Sdraws tweets...
- Wed May 30, 2018 11:03 pm
- Forum: ImetelChat
- Topic: Recent Interesting article
- Replies: 2
- Views: 4680
- Fri May 25, 2018 5:46 pm
- Forum: ImetelChat
- Topic: Imetelstat....real life story
- Replies: 3
- Views: 8859
Re: Imetelstat....real life story
Jingle, what you have posted is very relevant in terms of history but is unfortunately not current. I was honored to communicate directly with Irish for a few years while John was receiving therapy at Mayo. His progress was remarkable and he did go from advanced disease to CR/PR status. Unfortunatel...
- Fri May 25, 2018 4:11 am
- Forum: ImetelChat
- Topic: Geron is setting the stage to raise capital, a lot of it.
- Replies: 0
- Views: 3459
Geron is setting the stage to raise capital, a lot of it.
I was asked privately to comment on this. I completely missed the ATM sale pointed out by phil but not this time, no one can. While some have suggested Geron needs the money because J and J plans to walk and Geron will have to "go it alone", something fearless JS says he would do with no hesitation,...