Search found 1665 matches

by biopearl123
Tue Oct 24, 2023 3:39 pm
Forum: ImetelChat
Topic: MAIA
Replies: 1
Views: 661

MAIA

by biopearl123
Tue Oct 24, 2023 3:38 pm
Forum: ImetelChat
Topic: new article today
Replies: 6
Views: 2531

Re: new article today

You are totally right about cash burn.
by biopearl123
Tue Oct 24, 2023 12:49 am
Forum: ImetelChat
Topic: new article today
Replies: 6
Views: 2531

Re: new article today

Thanks for posting Jayfish, considering we have heard plenty from KOLs already, virtually all of which has been positive, I think an ADCOM is a positive event and will give voice to patient advocates, patients and physicians. The costly delay foisted on Geron and patients is shameful. What could pos...
by biopearl123
Mon Oct 23, 2023 7:59 pm
Forum: ImetelChat
Topic: Wither Lancet?
Replies: 2
Views: 1554

Wither Lancet?

We know the article presenting the PIII MDS data should be published in the widely read, highly regarded medical journal, Lancet should be out any week now. Also waiting on ASH abstracts (Nov 2), update on oral telomerase inhibitor and enrollment status of ongoing studies. MF trial enrollment still ...
by biopearl123
Sun Oct 22, 2023 9:13 pm
Forum: ImetelChat
Topic: ADCOM
Replies: 96
Views: 292162

Re: ADCOM

As noted, Imetelstat is not on the ADCOM agenda for Nov 16th.
by biopearl123
Sat Oct 14, 2023 9:35 pm
Forum: ImetelChat
Topic: ADCOM
Replies: 96
Views: 292162

Re: ADCOM

I don’t think they want more time to review. They have had plenty. I just think they are a top heavy institution (18,000 employees), that can’t get out of its own way.
by biopearl123
Fri Oct 13, 2023 5:17 pm
Forum: ImetelChat
Topic: ADCOM
Replies: 96
Views: 292162

Re: ADCOM

Lewis, this is very likely not a true statement and you should verify if you think it is. Who do you think is paying for Imetelstat for “anyone who needs it?”. I don’t think Geron is giving it away and I don’t know if insurance is providing coverage, do you? Geron is not a philanthropic organization...
by biopearl123
Fri Oct 13, 2023 3:05 am
Forum: ImetelChat
Topic: New Careers Listing - Head of IP
Replies: 2
Views: 4691

Re: New Careers Listing - Head of IP

Interesting. Defending from whom? MAIA or vice versa?
by biopearl123
Wed Oct 11, 2023 5:59 pm
Forum: ImetelChat
Topic: ADCOM
Replies: 96
Views: 292162

Re: ADCOM

LWS, the lesson has been taught many times over, there is no sure thing with Geron. I would caution you not to think in terms of absolutes. We have no idea what is in the heads of the FDA officials. We do know they did not think enough of Imetelstat to grant priority review. That fact alone is worth...
by biopearl123
Wed Oct 11, 2023 5:56 am
Forum: ImetelChat
Topic: What’s next?
Replies: 9
Views: 9494

Re: What’s next?

Kmall also to your point, there was a time when shareholders could physically go to a meeting and ask questions and follow ups. Now with the current format of submitting only written questions that may or may not be addressed does smack of control and disregard for shareholders. It’s a little like h...
by biopearl123
Wed Oct 11, 2023 12:14 am
Forum: ImetelChat
Topic: What’s next?
Replies: 9
Views: 9494

Re: What’s next?

Kmall, can’t say as I blame you. I have had many black cloud days with this company. All I am say is I think you will be back.

Ryan, if we don’t get plenary recognition this Dec we never will.
by biopearl123
Wed Oct 11, 2023 12:08 am
Forum: ImetelChat
Topic: ADCOM
Replies: 96
Views: 292162

Re: ADCOM

LWS until the agenda says Geron, it ain’t happening.
by biopearl123
Mon Oct 09, 2023 8:30 pm
Forum: ImetelChat
Topic: What’s next?
Replies: 9
Views: 9494

What’s next?

Short term we can anticipate major publication in Lancet. Then it’s only less than a month for the release of the ASH abstracts (Nov 2nd). Maybe more on status of ongoing studies and lymphoma and oral agent development updates. Best Wishes to all. bp
by biopearl123
Tue Oct 03, 2023 9:57 pm
Forum: ImetelChat
Topic: A reassuring review with big name authors
Replies: 1
Views: 4899

A reassuring review with big name authors

While we wait its always good to return to basics and listen to the KOL’s:

https://ashpublications.org/bloodadvanc ... in-myeloid
by biopearl123
Mon Oct 02, 2023 8:16 pm
Forum: ImetelChat
Topic: FDA shoot first ask questions later…
Replies: 0
Views: 14075

FDA shoot first ask questions later…

Does the FDA ever ask for advice or are they just imperious:

https://www.nejm.org/doi/full/10.1056/N ... 1833692513
by biopearl123
Mon Oct 02, 2023 4:54 pm
Forum: ImetelChat
Topic: Putting 6-thio-Dg into perspective
Replies: 15
Views: 14407

Re: Putting 6-thio-Dg into perspective

Here’s a report funded by MAIA, clearly not free of bias therefore. I would encourage a revisit to the question as to who controls the patent on 6-thio-Dg. Anyway we shouldn’t lose sight of the ties between MAIA, Sergei and Jerry Shay. I know I have read patent filings remotely that seemed to includ...
by biopearl123
Mon Oct 02, 2023 4:28 pm
Forum: ImetelChat
Topic: Putting 6-thio-Dg into perspective
Replies: 15
Views: 14407

Putting 6-thio-Dg into perspective

Worth continued watching, here’s a good place to start:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4293221/