Search found 210 matches

by biopearl123
Sun Mar 31, 2019 1:21 am
Forum: ImetelChat
Topic: New Board appointees
Replies: 0
Views: 827

New Board appointees

Everyone is probably aware of the new board appointees. They are impressive and have been granted generous stipends and options, here's the link:

http://ir.geron.com/news-releases/news- ... rd-members
by biopearl123
Fri Mar 22, 2019 5:56 am
Forum: ImetelChat
Topic: A reminder
Replies: 0
Views: 891

A reminder

As board moderator I have set up some what I think are reasonable ground rules to keep discussions relevant and civil. I encourage in depth discussion but I will not allow ad hominem attacks. If you have differences with a poster's ideas, state your arguments but do not attack the individual himself...
by biopearl123
Thu Mar 21, 2019 9:02 pm
Forum: ImetelChat
Topic: Kmall's 100 Day Campaign
Replies: 11
Views: 1598

Re: Kmall's 100 Day Campaign

Kmall, almost everyone with whom I have communicated and there have been many, who are interested in this drug, on the board or privately, has lost family and friends. I personally have been hit hard with the loss of family and Fish Sr and Irish became correspondence friends over several years time....
by biopearl123
Thu Mar 21, 2019 4:37 pm
Forum: ImetelChat
Topic: Kmall's 100 Day Campaign
Replies: 11
Views: 1598

Re: Kmall's 100 Day Campaign

Welcome Kamall and best wishes for the success of your campaign. bp
by biopearl123
Thu Mar 21, 2019 5:29 am
Forum: ImetelChat
Topic: EMA
Replies: 5
Views: 1280

Re: EMA

Gwikley, I appreciate your enthusiasm. Might be worth a gander at hunts musings on confirmation bias! :)
by biopearl123
Wed Mar 20, 2019 8:44 pm
Forum: ImetelChat
Topic: Confirmation Bias, is there a way through it?
Replies: 9
Views: 1905

Re: Confirmation Bias, is there a way through it?

Hunt, a marvelous Geron manifesto, thank you for posting and sharing your thoughts. Actually there has not been too much negativity on this board (unlike SA for example) and we were all in shock and traumatized by the Janssen decision. CB and your analysis of it is pertinent. Speaking for myself onl...
by biopearl123
Wed Mar 20, 2019 7:46 pm
Forum: ImetelChat
Topic: EMA
Replies: 5
Views: 1280

Re: EMA

Gwikley, I recall (from memory only) the EMA granting orphan status but not fast track, can you please post a link? The stock appears to be recovering nicely, it would be wonderful if there was EMA support. Thanks bp
by biopearl123
Fri Mar 08, 2019 6:12 pm
Forum: ImetelChat
Topic: Today's conference call
Replies: 2
Views: 1180

Re: Today's conference call

Ryan, I stand corrected, thank you. My recollection was 6 when Dr. O left but clearly not when Dr. S arrived, you are right. Yes the call was upbeat but I didn't see much new when one considered the prior info release regarding the new hires, planned expansion etc. I do think there is a sub rosa sea...
by biopearl123
Fri Mar 08, 2019 3:47 am
Forum: ImetelChat
Topic: Today's conference call
Replies: 2
Views: 1180

Today's conference call

Today's call sadly had no new information. Confirmation of MDS PIII with structure pretty much as outlined on clinical trials site. Just a bit of history, when JS took over the company seven or eight years ago the stock was selling for about 6. bp
by biopearl123
Thu Feb 21, 2019 7:53 pm
Forum: ImetelChat
Topic: Far from a straight line but still on course
Replies: 8
Views: 1685

Re: Far from a straight line but still on course

Ashah and Hunt (as always,--censorship? preposterous say what you will--within reason of course!), thank you for these contributions to the board. Ashah, I can assure you you are in good company and many here have losses that exceed your own. I do think Scarlett's hands are tied until he has full co...
by biopearl123
Thu Feb 21, 2019 7:26 pm
Forum: ImetelChat
Topic: Geron Jobs and Personnel
Replies: 10
Views: 3778

Re: Geron Jobs and Personnel

Hunt, thanks for updating this information. It seems pretty clear that there is a plan in place and Geron is gearing up. I suspect by the time the next quarterly update occurs, and it should be soon, the control should be back in Geron's hands and we should get some significant details. I am sure Dr...
by biopearl123
Thu Feb 14, 2019 10:22 pm
Forum: ImetelChat
Topic: Of general interest to the board
Replies: 2
Views: 1076

Of general interest to the board

https://patents.google.com/patent/US20190030064A1/en

First author on this patent application which embodies the MDS data from ASH is Dr. Rizo. Hope this helps lift some spirits. bp, your friendly board moderator.
by biopearl123
Wed Jan 30, 2019 8:31 pm
Forum: ImetelChat
Topic: Another one bites the dust
Replies: 0
Views: 1253

Another one bites the dust

Todays financial news reported yet another failed study, this time in Alzheimer's disease sponsored by Genentech. Recent news has reported cessation of studies in lung cancer and pancreatic cancer for lack of efficacy as well. Its not for lack of trying but it is clear that big Pharma is trying to g...
by biopearl123
Sat Jan 26, 2019 11:34 pm
Forum: ImetelChat
Topic: Brainstorm thread for activist role
Replies: 6
Views: 1989

Re: Brainstorm thread for activist role

Ryan, thank you for posting. You have been a reasoned champion for Imetelstat for as long as I can remember. Your comments as always are appreciated. In this case I think I would agree with much of what you have said but I think some things need to be tempered. For example, we ofter hear about "tant...
by biopearl123
Sat Jan 26, 2019 7:44 pm
Forum: ImetelChat
Topic: Brainstorm thread for activist role
Replies: 6
Views: 1989

Re: Brainstorm thread for activist role

kara, by rough head count we can raise about 2 million votes, those posted publicly and privately. This is a long way from the 3 % required to get a name on the ballot much less garner votes from institutional holders. Not sure where to go with this. Any board members with experience can weigh in wi...
by biopearl123
Mon Jan 21, 2019 11:01 pm
Forum: ImetelChat
Topic: Random musings on things I don’t understand
Replies: 9
Views: 2188

Re: Random musings on things I don’t understand

Almost half of patients (47%) stoped study drug because of 1. Lack of efficacy, 2. Physician decision 3. Patient decision. As I continue to think more about this I return to Buckminster Fuller. Almost half of the patients who withdrew or were withdrawn could not know they might be butterflies. Optim...
by biopearl123
Mon Jan 21, 2019 7:23 pm
Forum: ImetelChat
Topic: Random musings on things I don’t understand
Replies: 9
Views: 2188

Re: Random musings on things I don’t understand

Kara, it appears that 7 patients remained on trial as of the April data eval at 24 weeks. The investigators and the company do not appear to have shared how many patients remained on drug if any at the time of the Oct MOS determination. Yet another glaring omission of pertinent data. bp