Search found 210 matches

by biopearl123
Tue Apr 23, 2019 4:35 am
Forum: ImetelChat
Topic: A very basic note on other telomerase inhibitors
Replies: 4
Views: 1059

Re: A very basic note on other telomerase inhibitors

Rinconj, I think it’s pretty clear that imetelstat is trying to carve out “low risk (for aml ), high tx requirement niche. High risk pts you allude to are different, carry a poorer prognosis, and are clearly closer to aml. Since the discussion did not cover that pt population, your answer may lie th...
by biopearl123
Tue Apr 16, 2019 7:24 pm
Forum: ImetelChat
Topic: Another question for the upcoming meeting
Replies: 0
Views: 947

Another question for the upcoming meeting

First off Commisman and Kmall, great stuff, keep up the good work. I do hope some board members can make it to the meeting. I have posted some general questions previously but would like to add a request to get a breakdown as to how the new hires will be utilized, e.g. R and D, manufacturing, admini...
by biopearl123
Tue Apr 16, 2019 7:20 pm
Forum: ImetelChat
Topic: Notice to spammers
Replies: 0
Views: 854

Notice to spammers

We are starting to see some spam posters, advertisements etc. I will delete any extraneous posts immediately so don't waste your time. If you persist, I will suspend any new registrants and cut you off. Spam is not welcome on this board. bp
by biopearl123
Tue Apr 16, 2019 7:17 am
Forum: ImetelChat
Topic: Request to Bill W
Replies: 4
Views: 1082

Re: Request to Bill W

This was kindly provided by Hoosier Investor on SA: Hoosier Investor, Contributor Comments619 | Following BP, Conclusion: The International Search Report (ISR) is favorable on the patentability of the combination of Imetelstat + Venetoclax as a treatment for AML. Explanation: Two requirements must b...
by biopearl123
Mon Apr 15, 2019 7:57 pm
Forum: ImetelChat
Topic: Request to Bill W
Replies: 4
Views: 1082

Re: Request to Bill W

I have asked HI on SA to comment, he is very knowledgeable re patent law. bp
by biopearl123
Sat Apr 13, 2019 8:19 pm
Forum: ImetelChat
Topic: Worth watching this timely video
Replies: 3
Views: 1087

Re: Worth watching this timely video

Thanks Hunt, it actually wasn't my find. Hat tip to Richard on YMB for this one (and many others). bp
by biopearl123
Sat Apr 13, 2019 12:21 am
Forum: ImetelChat
Topic: Worth watching this timely video
Replies: 3
Views: 1087

Worth watching this timely video

http://www.managingmds.com/index.php?option=com_continued&view=material&Itemid=1233&course=155&nocredit=1&token=8088070b040224e7fec0c66dd2ba4ae9 Likelihood of approval is extremely high. Note discussion of disease modification. Dr. Steensma does not emphasize the more stringent entry criterion for I...
by biopearl123
Fri Apr 12, 2019 6:30 pm
Forum: ImetelChat
Topic: Request to Bill W
Replies: 4
Views: 1082

Request to Bill W

Cheng, for the benefit of the board would you consider a dispassionate (and I mean dispassionate) analysis of this paper and how this information might inform future combination studies? (If applicable at all.). Thanks, bp A non-natural nucleotide uses a specific pocket to selectively inhibit telome...
by biopearl123
Fri Apr 12, 2019 1:36 am
Forum: ImetelChat
Topic: Excellent summary of cc by Kmall
Replies: 2
Views: 1032

Re: Excellent summary of cc by Kmall

Kmall, of course! bp
by biopearl123
Wed Apr 10, 2019 6:20 pm
Forum: ImetelChat
Topic: Excellent summary of cc by Kmall
Replies: 2
Views: 1032

Excellent summary of cc by Kmall

Kmall since you have posted an excellent summary of the cc on YMB I will take that as implicit permission to re post here, thank you and keep up your "world travels"! Good morning board. During yesterdays call (which I was fortunate enough to have listened to twice) I took some notes to highlight wh...
by biopearl123
Wed Apr 10, 2019 1:21 am
Forum: ImetelChat
Topic: Today at Needham
Replies: 3
Views: 1036

Re: Today at Needham

by biopearl123
Tue Apr 09, 2019 11:13 pm
Forum: ImetelChat
Topic: Today at Needham
Replies: 3
Views: 1036

Today at Needham

Superb presentation by Dr. Scarlett easily accessible via Gwen site. I will try to post link later if someone doesn’t do it first. bp
by biopearl123
Sun Apr 07, 2019 9:14 pm
Forum: ImetelChat
Topic: Kmall - Global Update
Replies: 5
Views: 2370

Re: Kmall - Global Update

Kmall, I would love to see you take the record for "number of views". Keep up the good work! bp
by biopearl123
Sat Apr 06, 2019 6:48 am
Forum: ImetelChat
Topic: Where are the potential partners?
Replies: 7
Views: 1429

Re: Where are the potential partners?

That is my recollection as well. bp
by biopearl123
Sat Apr 06, 2019 12:40 am
Forum: ImetelChat
Topic: Where are the potential partners?
Replies: 7
Views: 1429

Re: Where are the potential partners?

Sargasso, thanks for responding. Actually I have to give Scarlett the benefit of the doubt. Yes the conference calls are frustrating since he only takes questions from the few remaining interested analysts. But the annual meeting has a different flavor. I think he really tries to answer questions si...
by biopearl123
Fri Apr 05, 2019 9:11 pm
Forum: ImetelChat
Topic: Where are the potential partners?
Replies: 7
Views: 1429

Re: Where are the potential partners?

Sargasso, Way not ask Scarlett directly in May?
by biopearl123
Fri Apr 05, 2019 1:09 am
Forum: ImetelChat
Topic: As we approach the annual meeting
Replies: 1
Views: 836

As we approach the annual meeting

First off welcome new members and thank you for your contributions. As we approach the annual meeting, it is the one time when Dr. Scarlett actually takes questions from shareholders, my wife is insisting I go but I will probably not make the substantial trip especially if some of our Californians w...
by biopearl123
Thu Apr 04, 2019 10:23 pm
Forum: ImetelChat
Topic: Commsman's Pitch for IMBARK Phase 3 to the Geron Executive Management Team
Replies: 3
Views: 1299

Re: Commsman's Pitch for IMBARK Phase 3 to the Geron Executive Management Team

Cheng, I think that fast track status conveys the privilege of more frequent meetings with the FDA and ongoing guidance regarding study design. This also allows for rolling submission of data. Even if the study design does not change from the original Janssen PIII, the FDA could confer an accelerate...
by biopearl123
Sun Mar 31, 2019 1:46 am
Forum: ImetelChat
Topic: "about Imetelstat"
Replies: 1
Views: 811

"about Imetelstat"

I always find the "fine print" which we all tend to gloss over, interesting. Looking back, there were allusions almost a year ago in the "forward looking statements", hints that Scarlett might go it alone with suggestions that Janssen may or may not continue the partnership etc. We know this all too...