Search found 303 matches

by biopearl123
Tue Mar 10, 2020 7:43 pm
Forum: ImetelChat
Topic: No Job Openings
Replies: 4
Views: 1540

Re: No Job Openings

Yes, its a special bird that snatches your money and flies away.
by biopearl123
Tue Mar 10, 2020 4:30 am
Forum: ImetelChat
Topic: No Job Openings
Replies: 4
Views: 1540

Re: No Job Openings

Also I see you have run into the irritating spell correction which always changes Geron into a bird. bp
by biopearl123
Tue Mar 10, 2020 4:28 am
Forum: ImetelChat
Topic: No Job Openings
Replies: 4
Views: 1540

Re: No Job Openings

musketeer, Well, either the jobs were filled or Scarlett decided not to hire them after all. The latter very unlikely since stock options were issued. It appears the Scarlett continues to build a team that has the intention of manufacturing and marketing Imetelstat. The question is when. bp
by biopearl123
Thu Mar 05, 2020 10:58 pm
Forum: ImetelChat
Topic: Geron quarterly call
Replies: 1
Views: 1263

Geron quarterly call

https://ir.geron.com/investors/press-re ... fault.aspx

Where"s the part about discussing "recent events"?
by biopearl123
Wed Mar 04, 2020 12:40 am
Forum: ImetelChat
Topic: Clinical trials site updates
Replies: 2
Views: 1561

Clinical trials site updates

The MF study is now listed as completed and the MDS study has had more sites added for a total of 58 sites recruiting. Since many of the enrolling sites are in South Korea, Italy and Israel it is reasonable to expect that enrollments in these centers will be delayed due to Covid-19. bp
by biopearl123
Sat Feb 29, 2020 6:37 pm
Forum: ImetelChat
Topic: Imet Angels - A grassroots movement
Replies: 4
Views: 2263

Re: Imet Angels - A grassroots movement

But Geron kept Sergei's patents.
by biopearl123
Sat Feb 29, 2020 6:31 pm
Forum: ImetelChat
Topic: Perspective on the MF field
Replies: 7
Views: 1796

Re: Perspective on the MF field

Bill, thank you for your contributions as always. One thing about the ongoing studies you cite and there are many listed, have you seen any that suggest actual disease modification? Even the last Abbvie Venetoclax study update released yesterday in AML did not statistically prolong life even though ...
by biopearl123
Sat Feb 29, 2020 6:26 pm
Forum: ImetelChat
Topic: Perspective on the MF field
Replies: 7
Views: 1796

Re: Perspective on the MF field

rccola335, the Italian study on MOS certainly raised an eyebrow, but the FDA in looking at RWD would probably take a magnifying glass to the actual statistical analysis such as looking carefully at age/disease matched controls to be sure the comparisons are valid between the treatment group and the ...
by biopearl123
Thu Feb 13, 2020 4:47 pm
Forum: ImetelChat
Topic: A Salute to Memom
Replies: 5
Views: 1984

Re: A Salute to Memom

Commsman, the evil and sadness of cancer has affected us all. Thank you for sharing this touching family story. bp
by biopearl123
Mon Feb 10, 2020 2:15 am
Forum: ImetelChat
Topic: Hat tip to hay flick YMB
Replies: 4
Views: 1612

Re: Hat tip to hay flick YMB

Ryan, I think you were the one who said Geron was screening on the basis of molecular signature and I took issue since there was no mention on the clinical trials site. Looks like you will tun out to be right for future use!! I hope so. Regards, bp
by biopearl123
Sun Feb 09, 2020 7:47 pm
Forum: ImetelChat
Topic: Hat tip to hay flick YMB
Replies: 4
Views: 1612

Re: Hat tip to hay flick YMB

Worth a read in light of the WIPO post:

https://www.nature.com/articles/leu2013 ... rigin=ppub
by biopearl123
Fri Jan 24, 2020 12:11 am
Forum: ImetelChat
Topic: Geron Home Page
Replies: 0
Views: 2503

Geron Home Page

For those of you who obsessively check Geron's home page (I do, but mostly out a a sense of obligation to this board) its pretty clear that the careers section hasn't been updated despite the high probability that the positions have been filled several weeks ago and the options that attach issued. S...
by biopearl123
Mon Jan 13, 2020 9:48 pm
Forum: ImetelChat
Topic: New Company presentation
Replies: 1
Views: 1367

New Company presentation

https://s24.q4cdn.com/668523011/files/doc_presentations/2020/Geron-Corporate-Presentation-JPM-Jan-2020-01.13.2020-FINAL.pdf A few observation about the new presentation. 1. Emphasis on new class and IP protection to 2033 (they will need it at this rate). 2. New PIII MDS proposals to FDA--this does n...
by biopearl123
Mon Dec 30, 2019 7:19 pm
Forum: ImetelChat
Topic: Parsing the obnubulate Scarlett
Replies: 6
Views: 2709

Re: Parsing the obnubulate Scarlett

STA, I agree completely with your thoughts. A combo study would probably be the slowest path, possibly requiring a PII first. I have been intrigued by this statement in the last PR: " (i) whether regulatory authorities permit the further development of imetelstat for relapsed/refractory MF before Ge...
by biopearl123
Fri Dec 27, 2019 4:14 pm
Forum: ImetelChat
Topic: 14 months since Gernobyl
Replies: 3
Views: 1753

Re: 14 months since Gernobyl

Signet 01, you are quite correct, but the CD was to be based largely on the MF data if I remember correctly. Later Scarlett said Janssen would also take the MDS data into consideration before making a final decision. Regards, bp
by biopearl123
Fri Dec 27, 2019 3:59 am
Forum: ImetelChat
Topic: 14 months since Gernobyl
Replies: 3
Views: 1753

14 months since Gernobyl

Well its been about 14 months since Gernobyl. Since that time (ignoring the stock price) some very good things have happened. We have a first class management and development team, fast track in two indications, money in the bank, optimistic meetings with the FDA and multiple signals that manufactur...
by biopearl123
Mon Dec 23, 2019 3:12 am
Forum: ImetelChat
Topic: Parsing the obnubulate Scarlett
Replies: 6
Views: 2709

Re: Parsing the obnubulate Scarlett

I would submit that that need is not met. Rux is a treatment for symptoms but has not been clearly associated with disease modification. With front line there is potential to change the course of a uniformly fatal disease. I think the potential to help many more patients live longer and better is be...