Search found 210 matches

by biopearl123
Sat Aug 31, 2019 7:48 pm
Forum: ImetelChat
Topic: 57 P3 Site Locations and Counting?
Replies: 8
Views: 2156

Re: 57 P3 Site Locations and Counting?

Back in the USA! Sorry for the radio silence, have been on a long anticipated retirement trip of a couple of weeks. Also have been trying to deal with the now several thousand bogus registration attempts. Someone (s) want to make this site unusable. Can only assume its is some form of short attack s...
by biopearl123
Sat Aug 17, 2019 4:35 am
Forum: ImetelChat
Topic: On vacation
Replies: 1
Views: 988

On vacation

Will be out of the country for a couple of weeks. Would appreciate it if any of our regulars can keep the board up to date. There is a good post from Stig on YMB and recent good discussions on SA. Best Wishes, bp
by biopearl123
Mon Aug 12, 2019 6:24 pm
Forum: ImetelChat
Topic: P III
Replies: 5
Views: 2203

Re: P III

Thanks 1boardersooner, I can't take credit for that nice summation, it belongs to Ryan, a long time contributor. bp
by biopearl123
Thu Aug 08, 2019 3:14 pm
Forum: ImetelChat
Topic: P III
Replies: 5
Views: 2203

P III

by biopearl123
Wed Aug 07, 2019 12:22 am
Forum: ImetelChat
Topic: Imetelstat: The First Disease-Modifying Drug for Myelodysplastic Syndromes?
Replies: 4
Views: 1515

Re: Imetelstat: The First Disease-Modifying Drug for Myelodysplastic Syndromes?

kara, I think the low valuation is a strong reflection of the disillusionment and disappointment that accompanied the Janssen rejection. Not to mention the litany of failed studies and unfulfilled promises. That ought to do it. To some however that strange sequence of events and marked depression of...
by biopearl123
Tue Aug 06, 2019 8:23 pm
Forum: ImetelChat
Topic: Imetelstat: The First Disease-Modifying Drug for Myelodysplastic Syndromes?
Replies: 4
Views: 1515

Re: Imetelstat: The First Disease-Modifying Drug for Myelodysplastic Syndromes?

Ryan, thanks for your comments and for the link. It is a very nice summation from EHA. Yes, first in class, new drug should get a little more respect. Your point about waiting three years is an important one and it appears the market is thinking just that. I think those who follow the company such a...
by biopearl123
Tue Aug 06, 2019 2:16 am
Forum: ImetelChat
Topic: Excellent blog on SA
Replies: 0
Views: 1361

Excellent blog on SA

One of our excellent posters has made some terrific contributions on SA and has some articles and blogs which are very worthwhile. Here is the latest:

Geron: The Dilution Solution. - Bridge to sell | Seeking Alpha
by biopearl123
Thu Jul 25, 2019 10:57 pm
Forum: ImetelChat
Topic: General Info
Replies: 10
Views: 2388

General Info

Fellow Board Members: Every day I check this board a few times in fulfillment of my responsibilities as moderator. There are usually a few requests for approval to post which I have granted with the exception of anything that looks like a robot or a potential spam generator. Today this board was bom...
by biopearl123
Tue Jul 16, 2019 8:50 pm
Forum: ImetelChat
Topic: Sdraw
Replies: 3
Views: 4496

Re: Sdraw

rinconj, I agree, it would be very reassuring to hear from him right about now. bp
by biopearl123
Tue Jul 16, 2019 6:30 am
Forum: ImetelChat
Topic: +Seems almost impolite to speak of here
Replies: 2
Views: 1389

Re: +Seems almost impolite to speak of here

Gwikley, I can offer no counter argument. This has been a terrible investment, but is probably one of the longest surviving independent biotechs and may yet cross the finish line. bp
by biopearl123
Mon Jul 15, 2019 6:18 pm
Forum: ImetelChat
Topic: Just for fun while we wait, a repost from SA
Replies: 4
Views: 1941

Re: Just for fun while we wait, a repost from SA

esf, great thought but there could be no combo therapy trials in patients without FDA approval but there is some likelihood that research continues in the lab with various combination therapies. bp
by biopearl123
Tue Jul 09, 2019 11:53 pm
Forum: ImetelChat
Topic: Clinical Trials MDS site update
Replies: 1
Views: 1730

Re: Clinical Trials MDS site update

MF study also upgraded today to reflect transfer to Geron sponsorship. Also "new" site added which is a little confusing since the study stopped enrolling some time ago. I suspect this addition represents a site contributing Real World Data on a patient(s) only to enhance the "control" arm data. bp
by biopearl123
Mon Jul 08, 2019 5:30 pm
Forum: ImetelChat
Topic: Clinical Trials MDS site update
Replies: 1
Views: 1730

Clinical Trials MDS site update

The clinical trials site has been updated to reflect apparent finalization of study sites and anticipated end of study dates. No surprises yet. If the primary end point is truly 8 weeks of TI (more likely the FDA would be moved by 24 week TI rates), then it seems possible that the data may be presen...
by biopearl123
Sun Jul 07, 2019 11:30 pm
Forum: ImetelChat
Topic: Just for fun while we wait, a repost from SA
Replies: 4
Views: 1941

Just for fun while we wait, a repost from SA

Reposted from SA: Here's a long shot. As the final protocol becomes public soon and since we know the PIII design will not change much if at all, this nagging "proprietary" study design hinted at by Scarlett has been tugging at me. Is it possible that there will be a "Secret Third Arm" (in honor of ...
by biopearl123
Wed Jul 03, 2019 11:19 pm
Forum: ImetelChat
Topic: Thoughts re the post EHA reprise
Replies: 0
Views: 1553

Thoughts re the post EHA reprise

Fellow board members, first off happy fourth of July. I never lose sight of the tremendous opportunities and safety this blessed country has provided me and my family. I am grateful to those who made it happen and keep us safe and strong. I have listened again to the recent Geron presentation and I ...
by biopearl123
Tue Jul 02, 2019 4:38 am
Forum: ImetelChat
Topic: Re the early Mayo data, my response to a question on YMB
Replies: 1
Views: 1466

Re the early Mayo data, my response to a question on YMB

We have talked a lot about the Mayo data in the past and lamented its apparent burial. I think we just have to accept that we will never get a final reckoning. This is a response I posted earlier today in this regard on the YMB: Cathy, The Mayo Clinic data was the first to show actual CRs and PRs. T...
by biopearl123
Sun Jun 30, 2019 7:52 pm
Forum: ImetelChat
Topic: OPERATION KMALL - That's A Wrap !!!
Replies: 1
Views: 1449

Re: OPERATION KMALL - That's A Wrap !!!

Kudos to Kmall, job well done. Cast your bread...bp
by biopearl123
Sat Jun 22, 2019 7:49 pm
Forum: ImetelChat
Topic: Tues conference
Replies: 5
Views: 2602

Tues conference

While Geron has been criticized for a meeting to "reprise" already reported data, I think lost in the noise are the words, Key, Opinion and Leaders. Lets hope we can glean more than just the presented data, but also look to these leaders in the field for Key Opinions. Also it has been mentioned else...