Search found 303 matches

by biopearl123
Sun Apr 26, 2020 11:29 pm
Forum: ImetelChat
Topic: Near term events
Replies: 3
Views: 1085

Re: Near term events

Me too, brother. As the Ram Bam said, if not now, when?
by biopearl123
Sun Apr 26, 2020 6:45 pm
Forum: ImetelChat
Topic: Enhancement of Myeloproliferative Stem Cells
Replies: 1
Views: 472

Re: Enhancement of Myeloproliferative Stem Cells

GREAT post earfool, thank you. This may explain the findings presented in the Hu poster at last year's ASH. bp
by biopearl123
Sun Apr 26, 2020 2:23 am
Forum: ImetelChat
Topic: New paper of interest
Replies: 1
Views: 545

Re: New paper of interest

by biopearl123
Sun Apr 26, 2020 12:29 am
Forum: ImetelChat
Topic: New paper of interest
Replies: 1
Views: 545

New paper of interest

https://www.sciencedirect.com/science/a ... 1X20307798

May turn up at EHA. No doubt Incyte taking careful note. Regards, bp
by biopearl123
Fri Apr 24, 2020 7:03 pm
Forum: ImetelChat
Topic: Near term events
Replies: 3
Views: 1085

Re: Near term events

Correction: EHA Abstract release May 14th.
by biopearl123
Thu Apr 23, 2020 11:12 pm
Forum: ImetelChat
Topic: Near term events
Replies: 3
Views: 1085

Near term events

Hello fellow board members, hope everyone is safe. Here is what we have to look forward to in the next few weeks: 1. Release of EHA abstracts, should be in first week of May 2. Results of FDA meeting, should be around mid May 3. Annual shareholders meeting June 5th 4. EHA virtual meetings second wee...
by biopearl123
Mon Apr 13, 2020 11:50 pm
Forum: ImetelChat
Topic: If you are looking for the new shareholders letter
Replies: 7
Views: 1209

Re: If you are looking for the new shareholders letter

Yes, Bill is an acquired taste. I have always felt he had much to contribute and I hope to see him eating some serious crow (not CRO ) soon if we see favorable action by the FDA. Bill despite his detractors is the only person I know who has worked directly with Imetelstat and contributed to the body...
by biopearl123
Sat Apr 11, 2020 8:31 pm
Forum: ImetelChat
Topic: Patience and balance are virtues needed for the Geron journey
Replies: 9
Views: 1858

Re: Patience and balance are virtues needed for the Geron journey

Hi Hunt, thank you for your contributions (as always) to this board. I generally agree with your assessment and feel the potential for Geron has been long underestimated and that were coming into exciting times. While I have agreed with your black swan theory in general, I am concerned that the actu...
by biopearl123
Thu Apr 09, 2020 6:40 pm
Forum: ImetelChat
Topic: If you are looking for the new shareholders letter
Replies: 7
Views: 1209

If you are looking for the new shareholders letter

If you are looking for the new shareholders letter, it is in plain sight on the Geron website. I missed it at first since there is nothing to identify it as new and it fades into the background of the design of the site. Basically the web site is insipid with that ridiculous rocking horse. Time for ...
by biopearl123
Sun Apr 05, 2020 6:50 pm
Forum: ImetelChat
Topic: Reality check
Replies: 8
Views: 1350

Re: Reality check

Blood tax services listed here at about 3600. https://www.hopkinsmedicine.org/the_johns_hopkins_hospital/_docs/jhh_charges.pdf I have seen other estimates closer to 7 to 8 hundred per unit. Cost has to consider collection, screening for blood borne disease (including it appears COVID19), preparation...
by biopearl123
Sat Apr 04, 2020 6:32 am
Forum: ImetelChat
Topic: Reality check
Replies: 8
Views: 1350

Re: Reality check

If there are 40,000 MDS cases in the US and Imet can be applied to 85% of them per Geron's slides, and if each patients Tx requirements goes down by 2 units every 2 months (12 units/year--this is very conservative but allows for not all MDS patients having a tx requirement), then 408,000 units of bl...
by biopearl123
Sat Apr 04, 2020 12:25 am
Forum: ImetelChat
Topic: Reality check
Replies: 8
Views: 1350

Re: Reality check

STA, anemia amelioration is an issue not only for MDS but also AML and MF (a secondary endpoint in the MF study). Your point is relevant, important and right on. The FDA, with low risk to them and to patients could allow compassionate use in high TR, lower risk patients based on the current data. It...
by biopearl123
Fri Apr 03, 2020 10:04 pm
Forum: ImetelChat
Topic: Reality check
Replies: 8
Views: 1350

Re: Reality check

STA, agree but there has to be blood available and blood from good donors which is getting scarcer.
by biopearl123
Fri Apr 03, 2020 3:25 am
Forum: ImetelChat
Topic: Reality check
Replies: 8
Views: 1350

Reality check

Today's PR is hardly surprising and I have mentioned in previous posts on SA and maybe here too that major contributing sites like Italy, Israel, South Korea will be literally shut down regarding ongoing clinical studies. I think we need to take a worse case look and assume that no new patients are ...
by biopearl123
Wed Apr 01, 2020 4:42 am
Forum: ImetelChat
Topic: Telomerase
Replies: 3
Views: 991

Re: Telomerase

Bill W (Chang ho) would be a good one to answer this but it would require him to take the question seriously and avoid a glib response. You question calls for an in depth scholarly response. I am asking Bill W our anyone equipped to answer, to rise to the challenge. bp
by biopearl123
Sun Mar 15, 2020 12:19 am
Forum: ImetelChat
Topic: AML - Q4
Replies: 6
Views: 2142

Re: AML - Q4

Ryan, my money is on AA. 3 groups providing RWD to bolster original Janssen study (7month), now with Moffit, Lake Success and Italian center should satisfy FDA if MOS in R/R patients in line with Moffit study. bp
by biopearl123
Sat Mar 14, 2020 5:57 pm
Forum: ImetelChat
Topic: Since everyone is on lockdown....
Replies: 1
Views: 1799

Since everyone is on lockdown....

Here is some interesting reading while we spend time at home. Geron is expanding R and D and not in a small way. They must think the money will come from somewhere e.g. a partner or AA. Love the optimism. Here is a recent article, note the conclusion section. Bill maybe give us your take? https://ww...
by biopearl123
Fri Mar 13, 2020 8:39 pm
Forum: ImetelChat
Topic: Parsing Scarlett yet again
Replies: 0
Views: 1178

Parsing Scarlett yet again

Fellow board members (for those who are left), it is very trying time not just for investors but most importantly patients and their families. The COVID-19 pandemic has affected us all and I wish those who are ill a speedy recovery and send condolences for those who have died. Even Scarlett addresse...
by biopearl123
Fri Mar 13, 2020 8:18 pm
Forum: ImetelChat
Topic: Good Bye
Replies: 4
Views: 1212

Re: Good Bye

karagozoglu, I have always appreciated your contribution to this board. Since the stock is at its lowest point in history, every stock owner who has held, shares your disappointment and have experienced losses (by definition). Best Wishes for future success and if you haven't sold I hope you (and th...