Search found 107 matches

by sargasso
Sat Sep 17, 2016 5:39 pm
Forum: ImetelChat
Topic: The MDS market
Replies: 7
Views: 3844

Re: The MDS market

Thanks Fisher! The information provided in your reply is very helpful. So GERN has two shots on goal: one directed at high risk MF and the other MDS. It appears to me if Imet receives approval (and I still have no good reason to believe it will not) it may first be for MDS. But of course that is onl...
by sargasso
Sat Sep 17, 2016 4:01 am
Forum: ImetelChat
Topic: The MDS market
Replies: 7
Views: 3844

Re: The MDS market

This is what I don’t understand: Sep 2, 2016 Incyte’s 2Q16 revenues “As we’ve already seen, Incyte (INCY) reported revenues of $246.3 million in its 2Q16 results. This converts to a 51% revenue growth in 2Q16 compared to $163 million in 2Q15. There’s increasing demand for Incyte’s Jakafi, the only F...
by sargasso
Fri Sep 16, 2016 10:25 pm
Forum: ImetelChat
Topic: The MDS market
Replies: 7
Views: 3844

The MDS market

GERN stated in its recent announcement: “Janssen has conducted an initial internal review of efficacy, safety and pharmacokinetic data from a subset of patients from Part 1 of IMergeTM and this review indicated that emerging safety and efficacy in IMergeTM is consistent with data reported from the p...
by sargasso
Thu Sep 15, 2016 6:01 pm
Forum: ImetelChat
Topic: Imetelstat Update: Some Thoughts
Replies: 11
Views: 6693

Re: Imetelstat Update: Some Thoughts

BP,

Thanks for your excellent reply to my post. Your post was very informative. Note to Irish: your posts are most appreciated.
by sargasso
Wed Sep 14, 2016 11:13 pm
Forum: ImetelChat
Topic: Imetelstat Update: Some Thoughts
Replies: 11
Views: 6693

Re: Imetelstat Update: Some Thoughts

An interesting post from the YMB. Are the observations made in this post valid? Are the below claims more or less correct? "In melancholy tone, CEO Scarlett stated that, "In the 9.4 mg/kg dosing arm, even though at the week 12 data assessment an insufficient number of patients met the protocol defin...
by sargasso
Tue Sep 06, 2016 5:49 pm
Forum: ImetelChat
Topic: Was wondering what the various reasons are to continue the expansion of the CTs over the next year or more?
Replies: 6
Views: 3556

Re: Was wondering what the various reasons are to continue the expansion of the CTs over the next year or more?

BP,

I'm not entirely sure I understand the following sentence. When time permits could you clarify? Thanks:

"Unless a malicious type substituted path slides something amazing really happened."
by sargasso
Sat May 28, 2016 8:59 pm
Forum: ImetelChat
Topic: Thinking Senyak? Think again
Replies: 7
Views: 8550

Re: Thinking Senyak? Think again

bp, It seems more likely than not to me that the sponsor of GERN’s clinical trials informed Irish not to disclose any further information about the ongoing results of these trials and specifically, the progress of her husband w/ regard to his participation in these trials. It is my understanding tha...
by sargasso
Wed May 18, 2016 9:28 pm
Forum: ImetelChat
Topic: A dusting of breadcrumbs
Replies: 7
Views: 3191

Re: A dusting of breadcrumbs

bp,

Thanks for your reply. Your post included lots of useful information! You appear to have a very good understanding of GERN and of biotech in general.
by sargasso
Fri May 13, 2016 6:30 pm
Forum: ImetelChat
Topic: A dusting of breadcrumbs
Replies: 7
Views: 3191

Re: A dusting of breadcrumbs

bp and others, I am confused about what type of information may be shared by GERN at ASCO concerning the results of the on-going clinical trials. Is the below information correct or incorrect? This is taken from the YMB and is a recent post. Is Hoosier correct? "Check this out by Hoosier Investor on...
by sargasso
Tue May 10, 2016 8:42 pm
Forum: ImetelChat
Topic: Some thoughts on the conference call, by Sdrawkcabeman
Replies: 6
Views: 6862

Re: Some thoughts on the conference call, by Sdrawkcabeman

Scott,

Thanks for your reply. I also believe a buy-out is the most likely outcome based upon the above observations of cabeman.
by sargasso
Mon May 09, 2016 4:39 pm
Forum: ImetelChat
Topic: Some thoughts on the conference call, by Sdrawkcabeman
Replies: 6
Views: 6862

Re: Some thoughts on the conference call, by Sdrawkcabeman

Sdrawkcabeman on the YMB has recently run a series of post as to why he believes a buy-out from JNJ is the most likely outcome for GERN. He notes: “What I see as pushing it off the fence towards a B/O is the board's posture. Look at the preparations they've made. From staff reduction, to lab closure...
by sargasso
Wed Apr 13, 2016 1:07 am
Forum: ImetelChat
Topic: Geron vs Incyte's valuation and Jakafi revenues
Replies: 5
Views: 4967

Re: Geron vs Incyte's valuation and Jakafi revenues

Fisher, Thanks. That's the kind of rough estimates I was looking for. From the first article I previously linked: "Jakafi revenues increased to $601 million in 2015 as compared to $355 million in 2014 due to the increase in volume as well as the price of Jakafi in the US. Jakafi revenues are further...
by sargasso
Tue Apr 12, 2016 8:49 pm
Forum: ImetelChat
Topic: Geron vs Incyte's valuation and Jakafi revenues
Replies: 5
Views: 4967

Geron vs Incyte's valuation and Jakafi revenues

It’s interesting to compare GERN (Imetelstat) to Incyte (Jakafi). I realize this comparison is way premature, problematic and inexact. Nonetheless this comparison may give us some idea of what the potential market is for Imetelstat. That is the only reason I make this comparison; to obtain some idea...
by sargasso
Mon Apr 11, 2016 3:24 pm
Forum: ImetelChat
Topic: GERN buy-out
Replies: 4
Views: 5043

Re: GERN buy-out

Fisher and bp,

Thanks to you both for your excellent response to my post. The quality of the information on this board in my opinion far exceeds that of the YMB so I am pleased that Fisher has established this board.
by sargasso
Sun Apr 10, 2016 10:01 pm
Forum: ImetelChat
Topic: GERN buy-out
Replies: 4
Views: 5043

GERN buy-out

I have concluded that my role on this board is to ask EDQ's (exceedingly dumb questions.) Here’s my question: There is, has been, lots of talk on the YMB about an eventually buy-out of GERN; discussion of bidding wars, offers from companies other than JNJ, etc. Most of this talk to me is simply hype...
by sargasso
Sat Apr 09, 2016 2:29 am
Forum: ImetelChat
Topic: A mystery
Replies: 7
Views: 4384

Re: A mystery

Fisher, Just to be clear I stand by my prior evaluation of GERN. I have assembled a thick research file on this stock. I performed all of the research contained in that file before I purchased my first share of GERN. That research has lead me to believe that imetelstat has a high probability of bein...
by sargasso
Fri Apr 08, 2016 1:30 am
Forum: ImetelChat
Topic: A mystery
Replies: 7
Views: 4384

Re: A mystery

bioperal, That was a very good post. Due to your post I now have a better understanding of why the present price of GERN appears low. Here's another mystery (sorry, that was an attempt at humor) given all of the reasons you listed why have you held this stock for 15 years? I mean you have given an e...
by sargasso
Thu Mar 24, 2016 11:39 pm
Forum: ImetelChat
Topic: A mystery
Replies: 7
Views: 4384

Re: A mystery

Fisher, I am receiving the definite impression that you are not terribly fond of my posts. There is apparently some sort of format I am supposed to follow on this board dictated by you that is unknown to me. I am simply attempting to state, Fisher, that given the potential of this drug and what we p...
by sargasso
Thu Mar 24, 2016 4:45 pm
Forum: ImetelChat
Topic: A mystery
Replies: 7
Views: 4384

A mystery

One of the largest mysteries about GERN is its current price. Given everything we have learned about imetelstat to date and given the fact that the drug has an excellent chance of approval; given GERN has a very capable partner and that imetelstat appears to be a first in class platform drug the pre...