Search found 33 matches
- Wed Jun 13, 2018 7:23 pm
- Forum: ImetelChat
- Topic: Goodbye
- Replies: 9
- Views: 13388
Re: Goodbye
So sorry to hear about your father. He created an incredible space for the discussion of MF and Imetelstat, and his personality came through in his often passionate writing. He'll be missed by many.
- Mon May 14, 2018 10:05 pm
- Forum: ImetelChat
- Topic: Questions for shareholders meeting
- Replies: 3
- Views: 3621
Re: Questions for shareholders meeting
Thanks for the response BP. There is so much written on Geron it's difficult to know what's been covered. And much information can be interpreted differently depending on your perspective. From Q4 2017 Geron Earnings Conference Call, Olivia Bloom: "For 2018 we are projecting an operating expense bur...
- Sun May 13, 2018 8:53 pm
- Forum: ImetelChat
- Topic: Questions for shareholders meeting
- Replies: 3
- Views: 3621
Re: Questions for shareholders meeting
Thanks BP. Where's Fish? Would like him to weigh in here if possible.
- Thu Apr 26, 2018 11:33 pm
- Forum: ImetelChat
- Topic: Quantitative analysis of Imetelchat
- Replies: 5
- Views: 4199
Re: Quantitative analysis of Imetelchat
Good Catch!
- Thu Apr 26, 2018 6:19 pm
- Forum: ImetelChat
- Topic: I have lost nearly all respect for SA
- Replies: 3
- Views: 3397
Re: I have lost nearly all respect for SA
Sargasso, perhaps you can post your response here. The current Alpha Exposure article is obviously written to accomplish a goal, and I despise it as I do pump pieces that also intentionally hide valuable information that might help to form a balanced view, and thus a more informed investment decisio...
- Thu Apr 26, 2018 7:39 am
- Forum: ImetelChat
- Topic: Quantitative analysis of Imetelchat
- Replies: 5
- Views: 4199
Quantitative analysis of Imetelchat
Not sure if this paper is referenced on ImetelChat....Quantitative analysis of imetelstat in plasma with LC–MS/MS using solid-phase or hybridization extraction (12/2017). Interesting to note at least three of the four authors are Janssen/Johnson & Johnson employees. Also interesting to view the 44 p...
- Wed Apr 11, 2018 11:18 pm
- Forum: ImetelChat
- Topic: Interesting news
- Replies: 1
- Views: 3341
Re: Interesting news
Prescient words; always appreciate your knowledge and intuition. You nailed it!
- Tue Mar 21, 2017 4:26 am
- Forum: ImetelChat
- Topic: A Comment on Seeking Alpha
- Replies: 5
- Views: 5341
A Comment on Seeking Alpha
Hi Fish, I thought I'd make a comment regarding the SA site. In my view, your posts are spot on and very well thought out; I've learned a lot from your site and writings. But, and I say this in a spirit of friendship, I believe it's counter-productive to engage with characters such as BM and Imetels...
- Mon Feb 13, 2017 7:59 pm
- Forum: ImetelChat
- Topic: Focus on Mechanism of Action
- Replies: 4
- Views: 4431
Re: Focus on Mechanism of Action
Agree Fish; If it’s determined for whatever reason(s) that Imetelstat isn’t having much affect on TI but is effective for other reasons, is that a big deal? It seems to me the narrative about Imetelstat has changed slightly over the last few CC's and wondering what your thoughts were. thx
- Sat Feb 11, 2017 8:21 pm
- Forum: ImetelChat
- Topic: Focus on Mechanism of Action
- Replies: 4
- Views: 4431
Focus on Mechanism of Action
The American Chemical Society recently put out a Top 40 list of Drugs in the Pipeline. Re. Imetelstat, they write: “Intriguingly, the data suggest that the drug is not altering telomerase activity, but instead acting through an alt. cellular mechanism to halt blood cell proliferation.” I recall duri...
- Wed Nov 02, 2016 6:10 am
- Forum: ImetelChat
- Topic: MF CTrials site updated
- Replies: 3
- Views: 3074
Re: MF CTrials site updated
Bio, you recently posted on SA some questions for someone to ask at the upcoming CC. I do believe anyone is able to call in and ask questions; perhaps you could do it yourself?
- Thu Jul 21, 2016 6:50 pm
- Forum: ImetelChat
- Topic: AML/MDS
- Replies: 2
- Views: 2546
AML/MDS
From Magic on SA: From the Yahoo board: Published on 19/07/2016 "Epigenetic landscape of the TERT promoter: a potential biomarker for high risk AML/MDS": Telomerase reverse transcriptase promoter;methylation profile;mutation analysis;acute myeloid leukaemia;survival curve Summary Although recent obs...
- Tue Jul 19, 2016 9:28 am
- Forum: ImetelChat
- Topic: Another S. Gryaznov article.
- Replies: 5
- Views: 5536
Another S. Gryaznov article.
Targeting homologous recombination and telomerase in Barrett's adenocarcinoma: impact on telomere maintenance, genomic instability and tumor growth. Lu R1, Pal J2, Buon L2, Nanjappa P2, Shi J3, Fulciniti M3, Tai YT3, Guo L4, Yu M4, Gryaznov S5, Munshi NC3, Shammas MA2. Author information: 11] Depart...
- Wed Jul 13, 2016 8:00 am
- Forum: ImetelChat
- Topic: PDCO
- Replies: 2
- Views: 2438
PDCO
Fisher, I think this was already posted, but like re-reading the interview with Dr. Sergei Gryaznov, I find it more stunning the second time. This is, again from last year's EMA PDCO (Pediatric) Minutes for the meeting on July 15-17 dated August 12, 2015 Janssen-Cilag International N.V; Treatment of...
- Wed Jul 13, 2016 7:30 am
- Forum: ImetelChat
- Topic: EMA action yesterday?
- Replies: 9
- Views: 7600
Re: EMA action yesterday?
Committee for Orphan Medicinal Products (COMP) Draft agenda for the meeting on 11-13 July 2016 Pre-meeting list of participants and restrictions in relation to declarations of interests applicable to the items of the agenda for the COMP plenary session to be held 11-13 July 2016. See July 2016 COMP ...
- Thu Jun 23, 2016 6:57 pm
- Forum: ImetelChat
- Topic: PRIME: new EU scheme for accelerated new drugs assessment/approval
- Replies: 1
- Views: 1735
- Tue Jun 07, 2016 5:03 pm
- Forum: ImetelChat
- Topic: Picture of Tefferi Poster at ASCO by Ruben Mesa
- Replies: 3
- Views: 3340
Re: Picture of Tefferi Poster at ASCO by Ruben Mesa
Thanks Bio. I think we can be reasonably confident John is still on the 7.5 dosage.
- Thu May 19, 2016 5:02 am
- Forum: ImetelChat
- Topic: Annual Meeting
- Replies: 6
- Views: 6588
Annual Meeting
The following was posted on Facebook @ Imet 33: Greg E. 5/18/16 Two other Shareholders and I were able to talk with Dr. Scarlett briefly after the Annual Meeting. As the meeting was now over, Dr. Scarlett said that he would answers questions at this time only if he felt he could. I asked him if he c...
- Wed May 18, 2016 9:16 pm
- Forum: ImetelChat
- Topic: Of bread crumbs and myeloma
- Replies: 11
- Views: 8233
Re: Of bread crumbs and myeloma
Hunting, I read he was treated with Revlimid, Velcade, and Dexamethasone.
- Fri May 13, 2016 6:08 pm
- Forum: ImetelChat
- Topic: "We have gotten positive feedback"
- Replies: 8
- Views: 5569
Re: "We have gotten positive feedback"
The question I have for the good doctor relates to "what's next" for Imetelstat. Any ideas on how to phrase the question for the best chance of response would be appreciated. I was reviewing an interview of Dr. Gryaznov, former employee of Geron by drkkd.com: "Dr. Gryaznov held the positions of Dire...