Search found 40 matches
- Tue Oct 02, 2018 2:57 am
- Forum: ImetelChat
- Topic: Recent events
- Replies: 3
- Views: 4194
Re: Recent events
My thoughts. If the ASH data were so good Janssen would have held on. I have no confidence in Scarlett and the board at this point. His statements of derisking the drug were very misleading and I think criminal to an SEC interpretation. I have been in this drug a long time and sold logging a loss th...
- Fri Aug 31, 2018 5:05 am
- Forum: ImetelChat
- Topic: Upcoming Catalysts
- Replies: 5
- Views: 11026
Re: Upcoming Catalysts
Bio, there are SEVERAL sessions where imet might be mentioned. Hanks for he link!
- Sun Aug 26, 2018 11:43 pm
- Forum: ImetelChat
- Topic: Do NOT sell
- Replies: 10
- Views: 15140
Re: Do NOT sell
Biopearl, As crazy as it sounds, I wonder if a lot of the questions you pose would not be cleared up were it not for th ASH info embargo. It is really unethical that the surprise value of a medical meeting would come before freeing up a new medication that might save a few lives between now and Dec....
- Mon Aug 20, 2018 4:51 am
- Forum: ImetelChat
- Topic: Just read a Fishermagnets post from 1/11/2016
- Replies: 2
- Views: 2910
Re: Just read a Fishermagnets post from 1/11/2016
BP I hope you are right in guessing the weight of Janssen vs. Geron. My suspicions at the time were based on the LFT elevations being so meaningless in the oncology world that Geron admitted they did not think them relavent to include in their initial reports. I hope whoever pulled the leverat the t...
- Sun Aug 19, 2018 2:44 pm
- Forum: ImetelChat
- Topic: Just read a Fishermagnets post from 1/11/2016
- Replies: 2
- Views: 2910
Just read a Fishermagnets post from 1/11/2016
He qoted Irish saying(paraphrased) that she had learned that cancer cures or near cures don’t come easy when there are competing interests. It seems that I am not the only one that thought the fda hold was fraudulent and desugned to give Incy and Celg some time. Why has there not been more made of t...
- Sun Aug 19, 2018 3:10 am
- Forum: ImetelChat
- Topic: New article in Blood re Jak inhibitors and lymphoid malignancy
- Replies: 4
- Views: 3660
Re: New article in Blood re Jak inhibitors and lymphoid malignancy
When I see articles like this and then consider the revenues the likes of Incyte and Celgene are bringing in for tx that is of very limited value, I have to believe someone was paid off at the FDA for the clinical hold on imet that almost ruined the company and greatly devalued GERN’s market cap. I ...
- Sat Aug 18, 2018 9:52 pm
- Forum: ImetelChat
- Topic: New article in Blood re Jak inhibitors and lymphoid malignancy
- Replies: 4
- Views: 3660
Re: New article in Blood re Jak inhibitors and lymphoid malignancy
BP, this is a pretty strong arguement for an alternative Tx for MF, MDS and would open the door for first line Tx once approved in the r/r setting. The authors’ demanding further investigation of Jak inhibitors being related to a 16 fold increase in likelihood of developing an aggressive lymphoma is...
- Sat Aug 18, 2018 9:51 pm
- Forum: ImetelChat
- Topic: New article in Blood re Jak inhibitors and lymphoid malignancy
- Replies: 4
- Views: 3660
Re: New article in Blood re Jak inhibitors and lymphoid malignancy
BP, this is a pretty strong arguement for an alternative Tx for MF, MDS and would open the door for first line Tx once approved in the r/r setting. The authors’ demanding further investigation of Jak inhibitors being related to a 16 fold increase in likelihood of developing an aggressive lymphoma is...
- Fri Aug 17, 2018 2:52 pm
- Forum: ImetelChat
- Topic: Blood Journal Article “How I Treat MF after failure of Jak inhibitor tx
- Replies: 1
- Views: 2331
Blood Journal Article “How I Treat MF after failure of Jak inhibitor tx
There was an interesting article in Bloodjournal.org back in Feb on treating MF patients failing Jak inhibitor tx. Very encouraging for imet prospects. Jak patient dropout and adverse effects noted makes the clinical hold on imet way back when even more fishy. Have no proof, but I would bet someone ...
- Fri Jul 20, 2018 1:25 am
- Forum: ImetelChat
- Topic: FDA Thoughts on Accelerated Approval
- Replies: 6
- Views: 8894
Re: FDA Thoughts on Accelerated Approval
I would agree, both of these are screeming both Imbark and Imerge! Just a matter of time.
Thanks for posting.
Thanks for posting.
- Sat Jun 23, 2018 9:16 pm
- Forum: ImetelChat
- Topic: Sdraw epic thesis
- Replies: 1
- Views: 2101
Sdraw epic thesis
For those who have not seen it, Sdraw has produced an epic thesis on where imet could go in combination therapies. It is a great tribute to the work Fishermagnets put in on this website over the years which helped many of us retain our sanity while we like salmon have swum continuously upstream wait...
- Sat Jun 23, 2018 9:12 pm
- Forum: ImetelChat
- Topic: More on the EHA presentation re marrow recovery
- Replies: 2
- Views: 3120
Re: More on the EHA presentation re marrow recovery
I think those bone marrow responses closely mirror the original Mayo study. BP, you probably have those numbers right at hand. This replication of results is of great significance, because, how many times have we seen one great set of results not reproduced in subsequent studies? History shows what ...
- Thu Jun 14, 2018 1:38 am
- Forum: ImetelChat
- Topic: Goodbye
- Replies: 9
- Views: 13410
Re: Goodbye
Fish Jr. I know how you must feel. The loss of a passionate father leaves a big hole. I appreciate the education many of us got from this message board. It is far more civilized than any other, thanks to your Dad’s diligence. I have a cousin recently diagnosed with MF, so it hits home to me. Hope yo...
- Sun Apr 15, 2018 11:52 pm
- Forum: ImetelChat
- Topic: (08-02-2018) - Janssen BioTech applies for global patent for combo treatment for hematologic cancers, incl imetelstat
- Replies: 5
- Views: 11578
Re: (08-02-2018) - Janssen BioTech applies for global patent for combo treatment for hematologic cancers, incl imetelsta
Fish, I am not averse to the horse pushing the cart every now and then!
- Sat Apr 14, 2018 11:51 pm
- Forum: ImetelChat
- Topic: (08-02-2018) - Janssen BioTech applies for global patent for combo treatment for hematologic cancers, incl imetelstat
- Replies: 5
- Views: 11578
Re: (08-02-2018) - Janssen BioTech applies for global patent for combo treatment for hematologic cancers, incl imetelsta
Fish and some of you more knowledgeable give me your thoughts here. My credentials are that I am an old MD, not a hematolgist, and I hated biochem, microbiology amd genetics in med school, but I do understand some of this stuff and Lord knows I have seen plenty of people with cancer in my practice o...
- Mon Apr 09, 2018 8:59 pm
- Forum: ImetelChat
- Topic: Reply to the short sellers
- Replies: 1
- Views: 2866
Re: Reply to the short sellers
More and more I feel we will see Imet as first line Tx, as discontinuation rate of Jakafi is pretty high.
- Wed Mar 28, 2018 6:10 pm
- Forum: ImetelChat
- Topic: Geron to present at 17th Needham Healthcare Conference on March 27, 2018
- Replies: 5
- Views: 8602
Re: Geron to present at 17th Needham Healthcare Conference on March 27, 2018
Lets just skip it next year!
- Wed Mar 28, 2018 5:46 pm
- Forum: ImetelChat
- Topic: Link to recent article on pancreatic cancer cell lines
- Replies: 2
- Views: 4879
Re: Link to recent article on pancreatic cancer cell lines
Some pretty heavy reading, but my if imet in combo with a parp could give pancreatic CA a good push back, now that would be huge. Pancreatic and glioblastoma are the final frontiers in oncology.
- Tue Mar 27, 2018 9:54 pm
- Forum: ImetelChat
- Topic: Needham conference
- Replies: 1
- Views: 2146
Re: Needham conference
It is available from the IR portal on the Geron site.
- Tue Mar 27, 2018 8:49 pm
- Forum: ImetelChat
- Topic: Needham conference
- Replies: 1
- Views: 2146
Needham conference
Can we listen to the webcast?