Search found 529 matches

by Fishermangents
Tue Jul 24, 2018 3:15 pm
Forum: ImetelChat
Topic: New members can register again!
Replies: 5
Views: 8554

New members can register again!

Hi all,

Due to some technical difficulties new members were unable to sign up for a while. I'm glad to announce this problem has been solved!

New members are once again welcome to register.

Regards,

Fish Jr.
by Fishermangents
Tue Jul 24, 2018 3:07 pm
Forum: ImetelChat
Topic: General Announcement from bio pearl
Replies: 6
Views: 11953

Re: General Announcement from biopearl

All,

I'd like to officially welcome Biopearl as Global Administrator!

I'm convinced that with his knowledge and dedication Biopearl will do a great job maintaining the high quality standard of discussion/content on this website.

Kind regards,

Fish Jr.
by Fishermangents
Wed Jun 13, 2018 2:10 pm
Forum: ImetelChat
Topic: Goodbye
Replies: 9
Views: 6458

Re: Goodbye

As to the future of Imetelstat.eu/ImetelChat: still unclear, will keep you posted.
by Fishermangents
Wed Jun 13, 2018 1:49 pm
Forum: ImetelChat
Topic: Goodbye
Replies: 9
Views: 6458

Goodbye

Dear reader, It is with great sadness that I announce the passing of my father and founder of this website, Fishermangents. He gave me his username and password before he died, as he became too weak to contribute in any way. "Fish" suffered from Myelofibrosis (MF) for which he received a stem cell t...
by Fishermangents
Sun Apr 15, 2018 11:11 pm
Forum: ImetelChat
Topic: (08-02-2018) - Janssen BioTech applies for global patent for combo treatment for hematologic cancers, incl imetelstat
Replies: 5
Views: 6364

Re: (08-02-2018) - Janssen BioTech applies for global patent for combo treatment for hematologic cancers, incl imetelsta

Great comments, thanks. For now I would stIck to hematolgic cancers and leave solid tumors aside. This patent is limited to that for very good and well researched reasons (medical, business), as we may expect from a partner like JnJ. It is this focus that adds to its strength.
by Fishermangents
Sat Apr 14, 2018 8:46 pm
Forum: ImetelChat
Topic: (08-02-2018) - Janssen BioTech applies for global patent for combo treatment for hematologic cancers, incl imetelstat
Replies: 5
Views: 6364

(08-02-2018) - Janssen BioTech applies for global patent for combo treatment for hematologic cancers, incl imetelstat

(08-02-2018) - Janssen BioTech applies for global patent for COMBINATION TREATMENT FOR HEMATOLOGICAL CANCERS, including Imetelstat. The present invention relates to a combination treatment for hematological cancers. More specifically; a combination of a telomerase inhibitor and a Bcl-2 inhibitor are...
by Fishermangents
Tue Mar 27, 2018 12:35 pm
Forum: ImetelChat
Topic: Link to recent article on pancreatic cancer cell lines
Replies: 2
Views: 2215

Re: Link to recent article on pancreatic cancer cell lines

Is on Imetelstat.info/pre-clinical Inhibitors of telomerase and poly(ADP-ribose) polymerases synergize to limit the lifespan of pancreatic cancer cells K.M. Burchett et al (2017) Imetelstat (GRN163L) is a potent and selective inhibitor of telomerase. We have previously reported that GRN163L could sh...
by Fishermangents
Tue Mar 27, 2018 12:29 pm
Forum: ImetelChat
Topic: Geron to present at 17th Needham Healthcare Conference on March 27, 2018
Replies: 5
Views: 3602

Re: Geron to present at 17th Needham Healthcare Conference on March 27, 2018

Difficult to say; I am not expecting real new things and I do believe known things to be confirmed. So in my opinion there is a good change of GERN going up further or there will be little profit taking. Both, on the longer term, are not that significant, so taking the momentum and setting aside som...
by Fishermangents
Fri Mar 23, 2018 10:07 am
Forum: ImetelChat
Topic: Geron to present at 17th Needham Healthcare Conference on March 27, 2018
Replies: 5
Views: 3602

Geron to present at 17th Needham Healthcare Conference on March 27, 2018

MENLO PARK, Calif., March 21, 2018 (GLOBE NEWSWIRE) -- Geron Corporation (GERN) today announced that John A. Scarlett, M.D., President and Chief Executive Officer, is scheduled to present at the 17th Annual Needham Healthcare Conference in New York at 4:00 p.m. Eastern Time on Tuesday, March 27, 201...
by Fishermangents
Thu Mar 22, 2018 9:12 pm
Forum: ImetelChat
Topic: Concerning anonymous short sellers
Replies: 5
Views: 4324

Re: Concerning anonymous short sellers

One of the measures a company can take is making sure that there is enough cash on board to bridge to success. So far Geron has anticipated to that. Suing manipulative short attacks is risky, as the shorters may use that to prove there is really something wrong. However, SEC should be able to step u...
by Fishermangents
Thu Mar 22, 2018 10:33 am
Forum: ImetelChat
Topic: How to join this board
Replies: 2
Views: 2987

Re: How to join this board

As you may have noticed the registration functionality is not activated. To become member please send an email to info@imetelstat.eu, mentioning your preferred username and valid email address. I will then contact you with your credentials.
by Fishermangents
Thu Mar 22, 2018 10:23 am
Forum: ImetelChat
Topic: In case Sdraw reads this board--repost from SA
Replies: 3
Views: 2244

Re: In case Sdraw reads this board--repost from SA

the Gupta PNAS article is great. Will add it to imetelstat.info soon.
by Fishermangents
Wed Mar 21, 2018 8:24 pm
Forum: ImetelChat
Topic: General Announcement--Assistant Moderator
Replies: 1
Views: 1543

Re: General Announcement--Assistant Moderator

Dear bio, I am honored and happy that you took up this role with me. Lets keep building this board into a concise and serious meetingplace for all those interested in telomerase, TI, imetelstat and Geron/JnJ.
by Fishermangents
Wed Mar 21, 2018 3:56 pm
Forum: ImetelChat
Topic: EMA Prime
Replies: 4
Views: 4152

Re: EMA Prime

If Median OS is not reached, that is good. In order to put the survivors into the perspective it is important how these survivors are doing, why they survive, even after Median OS has been achieved. That will give additional weight to the benefits and to see the depth of PR's and CR's and the target...
by Fishermangents
Wed Mar 21, 2018 3:46 pm
Forum: ImetelChat
Topic: OS vs median OS
Replies: 1
Views: 1808

Re: OS vs median OS

Wikipedia: 'Median survival, or "median overall survival" is also commonly used to express survival rates. This is the amount of time after which 50% of the patients have died and 50% have survived. In ongoing settings such as clinical trials, the median has the advantage that it can be calculated o...
by Fishermangents
Tue Mar 20, 2018 9:50 am
Forum: ImetelChat
Topic: Take aways from today's cc
Replies: 5
Views: 2648

Re: Take aways from today's cc

Transcript from Nasdaq / Fool Transcripts:
https://www.nasdaq.com/article/geron-ge ... t-cm936889
by Fishermangents
Tue Mar 20, 2018 9:44 am
Forum: ImetelChat
Topic: Take aways from today's cc
Replies: 5
Views: 2648

Re: Take aways from today's cc

Great summary, bio. Thanks.