Search found 23 matches
- Tue Nov 28, 2023 11:16 pm
- Forum: ImetelChat
- Topic: FDA Investigates Car T Immunotherapies
- Replies: 3
- Views: 3589
- Tue Nov 28, 2023 10:07 pm
- Forum: ImetelChat
- Topic: FDA Investigates Car T Immunotherapies
- Replies: 3
- Views: 3589
Re: FDA Investigates Car T Immunotherapies
This just came out today, Nov 28, 2023.
- Tue Nov 28, 2023 9:56 pm
- Forum: ImetelChat
- Topic: FDA Investigates Car T Immunotherapies
- Replies: 3
- Views: 3589
FDA Investigates Car T Immunotherapies
https://www.fda.gov/vaccines-blood-biologics/safety-availability-biologics/fda-investigating-serious-risk-t-cell-malignancy-following-bcma-directed-or-cd19-directed-autologous JNJ dropped the CD with Geron largely because they believed Car-T was the future of cancer treatments. This is a sad turn of...
- Thu Nov 16, 2023 1:26 pm
- Forum: ImetelChat
- Topic: Today the EMA Approves Modification to Imetelstat PIP
- Replies: 23
- Views: 14052
Re: Today the EMA Approves Modification to Imetelstat PIP
IMpress Phase 2 is an investigator-led study being led by The European Myelodysplastic Neoplasms Cooperative Group (EMSCO) and Australasian Leukaemia & Lymphoma Group (ALLG). Does this mean the primary funding for this trial comes from EMSCO and ALLG? Of course, I would presume the Imetelstat is don...
- Thu Nov 16, 2023 1:24 pm
- Forum: ImetelChat
- Topic: Today the EMA Approves Modification to Imetelstat PIP
- Replies: 23
- Views: 14052
Re: Today the EMA Approves Modification to Imetelstat PIP
@mck. I don't have any further details other than the link I provided in the 3rd post of this topic chain which opens the official EMA document which sanctions and approves the investigatory use of Imetelstat in children between the ages of 28 days and 18 years with MDS, JMML, and AML. I don't think...
- Thu Nov 16, 2023 1:10 pm
- Forum: ImetelChat
- Topic: Today the EMA Approves Modification to Imetelstat PIP
- Replies: 23
- Views: 14052
Re: Today the EMA Approves Modification to Imetelstat PIP
Sorry Biopearl. I didn't mean to suggest these trials are starting on Nov 13 2023 though I can see how my clumsy wording could be interpreted in that way. I meant to say these trials were officially approved in the EU by the EMA as of Nov 13, 2023.
- Tue Nov 14, 2023 8:49 pm
- Forum: ImetelChat
- Topic: Today the EMA Approves Modification to Imetelstat PIP
- Replies: 23
- Views: 14052
Re: Today the EMA Approves Modification to Imetelstat PIP
@ kmall - I don't know the exact changes made which is why I haven't said anything. I suspect the changes were to include the indications of MDS, JMML, and AML. I think previously approved conditions for Imetelstat investigations in EU children were brain cancer (which I believe was revoked at some ...
- Tue Nov 14, 2023 1:22 pm
- Forum: ImetelChat
- Topic: Today the EMA Approves Modification to Imetelstat PIP
- Replies: 23
- Views: 14052
Re: Today the EMA Approves Modification to Imetelstat PIP
Essentially, the EMA has adopted the proposed changes to the Pediatric Investigational Plan to allow a clinical trial for children with MDS, JMML and AML to commence as of Nov 13, 2023. The trial will have several stages where imetelstat is used in combination with 2 different chemotherapeutics and ...
- Tue Nov 14, 2023 4:58 am
- Forum: ImetelChat
- Topic: Today the EMA Approves Modification to Imetelstat PIP
- Replies: 23
- Views: 14052
Re: Today the EMA Approves Modification to Imetelstat PIP
Excellent point biopearl. Pediatric AML is a soul crushing form of cancer that gets a massive amount of media attention. We've all seen the pictures of little kids with bald heads in the news and research donation solicitations. If I'm reading these very early signs right, I think imetelstat may sho...
- Tue Nov 14, 2023 4:41 am
- Forum: ImetelChat
- Topic: Today the EMA Approves Modification to Imetelstat PIP
- Replies: 23
- Views: 14052
Re: Today the EMA Approves Modification to Imetelstat PIP
https://www.ema.europa.eu/en/medicines/ ... p03-20-m01
Here is a link to the EMA Approval Document. Near the bottom just under the field "DECISION" is the pdf document that was adopted by the EMA on Nov 13, 2023.
Here is a link to the EMA Approval Document. Near the bottom just under the field "DECISION" is the pdf document that was adopted by the EMA on Nov 13, 2023.
- Tue Nov 14, 2023 2:52 am
- Forum: ImetelChat
- Topic: Today the EMA Approves Modification to Imetelstat PIP
- Replies: 23
- Views: 14052
Today the EMA Approves Modification to Imetelstat PIP
Just today, Nov 13, 2023, the European Medicines Agency approved a modification to the Imetelstat Paediatric Investigation Plan to allow imetelstat to be administered to children between the ages of 28 days and 18 years with MDS, JMML, or AML. Why, and why now? This comes out just on the heels of th...
- Wed Feb 12, 2020 4:48 pm
- Forum: ImetelChat
- Topic: A Salute to Memom
- Replies: 5
- Views: 4418
A Salute to Memom
A Salute to Memom (pronounced mee-mom) A little over 6 ½ years ago, My Grandmother turned 90. In the spring of 2013, we had a huge family reunion for her to celebrate her 90s. Every single living descendant of hers with the exception of 1 grandchild was present to celebrate her 90th birthday. Notabl...
- Mon Feb 03, 2020 8:51 am
- Forum: ImetelChat
- Topic: Imet Angels - A grassroots movement
- Replies: 4
- Views: 4732
Imet Angels - A grassroots movement
I Met Angels We sure do have a strange way to conduct medical research! Ideally, medical science should be allowed to conduct true scientific research to find the most effective medical treatments and medicines without financial interests to dictate the priorities of the research. But here’s the rub...
- Sun Feb 02, 2020 6:02 pm
- Forum: ImetelChat
- Topic: Imetelstat May Become a Blockbuster Drug by Being 2nd?!?
- Replies: 1
- Views: 2973
Imetelstat May Become a Blockbuster Drug by Being 2nd?!?
Imetelstat May Become a Blockbuster Drug by Being 2nd?!? Abraham Lincoln became one of the most remembered and celebrated Presidents of the United States of America by being 2nd! Strange but true. You see, when Abraham Lincoln went to Chicago in May of 1860 for the Republican National Convention, he...
- Sun Feb 02, 2020 9:35 am
- Forum: ImetelChat
- Topic: Avalanch of Classaction Lawsuits
- Replies: 1
- Views: 2538
Avalanch of Classaction Lawsuits
Avalanche of Class-action Lawsuits Opened Against Geron. Last Thursday’s class action lawsuit avalanche is obviously a coordinated attack on Geron designed by the short cabal to rattle investor faith in the company, and to force the company to waste time, energy, and resources on legal battles inste...
- Sun Nov 17, 2019 9:42 pm
- Forum: ImetelChat
- Topic: Sequential Therapies are the Future of Cancer Treatments
- Replies: 0
- Views: 3713
Sequential Therapies are the Future of Cancer Treatments
“Title: Combination Treatment with Imetelstat, a Telomerase Inhibitor, and Ruxolitinib Depletes Myelofibrosis Hematopoietic Stem Cells and Progenitor Cells (Abstract #2963) Session Name: 635. Myeloproliferative Syndromes: Basic Science: Poster II Session Date: Sunday, December 8, 2019 Session Time: ...
- Thu Apr 25, 2019 6:01 am
- Forum: ImetelChat
- Topic: Salute to the Janssen Ladies of Geron! by Commsman
- Replies: 0
- Views: 3613
Salute to the Janssen Ladies of Geron! by Commsman
Greetings Imetelchat Community, Here is a post of mine that was deleted from the Yahoo Message Board, but I polished it a little and cleaned up a couple parts to ensure compliance with the forum rules. Always take advantage of a 2nd chance! I hope it’s ok for me to share these thoughts and observati...
- Wed Apr 17, 2019 8:24 am
- Forum: ImetelChat
- Topic: Update to Commsman's Pitcht for IMBARK PHASE III to the Geron Executive Management Team and Board of Directors
- Replies: 3
- Views: 3577
Re: Update to Commsman's Pitcht for IMBARK PHASE III to the Geron Executive Management Team and Board of Directors
kmall that is just TOO funny!!! I could just see Meatloaf going in there with 3 envelopes and successfully delivering two!
: - D
Bwaahaha!!
: - D
Bwaahaha!!
- Tue Apr 16, 2019 10:38 am
- Forum: ImetelChat
- Topic: Update to Commsman's Pitcht for IMBARK PHASE III to the Geron Executive Management Team and Board of Directors
- Replies: 3
- Views: 3577
Re: Update to Commsman's Pitcht for IMBARK PHASE III to the Geron Executive Management Team and Board of Directors
Truthfully, there is no real material difference from my original e-mail, but I felt much more confident that the words I had chosen were what was presented, and that all the little mistakes were fixed. I was also able to see exactly how it would be presented to the intended recipients. Life doesn’t...
- Tue Apr 16, 2019 10:31 am
- Forum: ImetelChat
- Topic: Update to Commsman's Pitcht for IMBARK PHASE III to the Geron Executive Management Team and Board of Directors
- Replies: 3
- Views: 3577
Update to Commsman's Pitcht for IMBARK PHASE III to the Geron Executive Management Team and Board of Directors
On Tuesday, April 9 at approximately 1:30 pm Eastern Time, I received the below e-mail from investor relations: “Hello Cxxxxxxx, Thank you for your interest in Geron, your feedback is appreciated. Stockholders wishing to communicate with the Board, or with a specific Board member, may do so by writi...