Search found 30 matches

by Gwikley
Wed Jun 12, 2019 4:47 am
Forum: ImetelChat
Topic: The 2019 Annual Shareholders Meeting: My thoughts.
Replies: 13
Views: 1312

Re: The 2019 Annual Shareholders Meeting: My thoughts.

Thank you for your devotion and excellent summary of your take, and interactions, at the meeting!! Kudos!
by Gwikley
Thu May 30, 2019 6:24 am
Forum: ImetelChat
Topic: Hard times for the lowly investor
Replies: 1
Views: 302

Hard times for the lowly investor

Share price and such are never a topic here. Perhaps rightfully so. Suffice it to say that it is NOT a good time for the lowly investor in this co. And I do not see that changing any time soon.
by Gwikley
Fri May 17, 2019 4:50 am
Forum: ImetelChat
Topic: An end run...
Replies: 2
Views: 729

An end run...

The extended time frames are disappointing. But the idea of a sit down with the FDA and trying an end run around needing a dual trial for MF given the current stats, is a novel idea worth pursuing. Kudos for the crew that came up with it
by Gwikley
Thu May 16, 2019 5:11 am
Forum: ImetelChat
Topic: May 16th it is - Yet Another Day of Anticipation
Replies: 10
Views: 1728

Re: May 16th it is - Yet Another Day of Anticipation

At some point in this progression it seems as though the left hand has no idea of what the right hand is doing. Rhetorical question is why is there such a disconnect between the stats offered by the sub-group of 13, and the FDA's apparent indifference to the same? OS is the standard. As it should be...
by Gwikley
Fri May 03, 2019 11:50 pm
Forum: ImetelChat
Topic: May 16th it is - Yet Another Day of Anticipation
Replies: 10
Views: 1728

Re: May 16th it is - Yet Another Day of Anticipation

And this CT filing adds to the mystery.
by Gwikley
Thu Apr 25, 2019 3:07 am
Forum: ImetelChat
Topic: ? Can Geron proceed to a P3 w/o JnJ data
Replies: 4
Views: 764

? Can Geron proceed to a P3 w/o JnJ data

Was said that it would take a full year to return all data. Dated from the 9/28 CD, that puts full return in the Fall. Would/could Geron open a P3 without that data secured and analyzed? Seems the $$ burn rate, if extended until sometime in the Fall, would necessitate the share offering sooner rathe...
by Gwikley
Thu Mar 21, 2019 3:15 am
Forum: ImetelChat
Topic: EMA
Replies: 5
Views: 998

Re: EMA

My apology. You are correct. Fast track, no. Orphan status, yes.
Blinded by wishful thinking, I suppose.
by Gwikley
Wed Mar 20, 2019 4:35 pm
Forum: ImetelChat
Topic: EMA
Replies: 5
Views: 998

EMA

EMA granted fast track to IMET in '15..... IMO approval for MF will come from them before the FDA.
by Gwikley
Sun Feb 03, 2019 1:29 am
Forum: ImetelChat
Topic: And Scarlett goes for the gold medal...
Replies: 1
Views: 1050

Re: And Scarlett goes for the gold medal...

Have to give him some kudos for his choices here and w/ Rizo etc. The CRO and the Dr. are top of the line. Redemption is full his if he can pull this off.
by Gwikley
Sun Jan 20, 2019 1:04 am
Forum: ImetelChat
Topic: Approval
Replies: 1
Views: 1058

Approval

Without a major firms marketing, sales force, contacts and it's own reputation, approval of this drug is, in and of itself, not a blanket guarantee that it will have a commercial success. One of the downsides of the loss of the JnJ partnership. Going it alone, through the P3, and beyond ....to the m...
by Gwikley
Mon Jan 14, 2019 3:23 am
Forum: ImetelChat
Topic: Response to Gwikley query
Replies: 3
Views: 1084

Re: Response to Gwikley query

Once again, thank you for your efforts. Much Appreciated.
by Gwikley
Sat Jan 12, 2019 5:16 pm
Forum: ImetelChat
Topic: Response to Gwikley query
Replies: 3
Views: 1084

Re: Response to Gwikley query

Thank You.
by Gwikley
Fri Jan 11, 2019 8:52 pm
Forum: ImetelChat
Topic: Combo Patents
Replies: 1
Views: 606

Combo Patents

Someone with more knowledge than I, please explain how those Pharmas that have taken out combo patents, using Imet paired with their own drug, can do so without a license or at least some kind of contractual agreement with Geron? Thanks in advance.
by Gwikley
Mon Dec 24, 2018 3:37 am
Forum: ImetelChat
Topic: Letter to Dr. Scarlett
Replies: 23
Views: 4201

Re: Letter to Dr. Scarlett

Your are to be commended for your insightful letter and the intents behind it. Sad to realize that the company has a standing policy not to respond, except in boiler plate, cliche hyperbole. But good effort anyway.
by Gwikley
Sat Dec 15, 2018 10:51 pm
Forum: ImetelChat
Topic: What did JS et al at Geron, learn about the science during the Janssen saga?
Replies: 8
Views: 2562

Re: What did JS et al at Geron, learn about the science during the Janssen saga?

Constantly amazed at the plodding, hesitant and (still) cumbersome process(es) used by the FDA. Granted, protection is their mission. And appreciated. However, from a patients view point, if a drug candidate has controllable toxicity, and statistically gives just ONE MORE DAY to live, where is the j...
by Gwikley
Wed Dec 12, 2018 2:15 am
Forum: ImetelChat
Topic: GERON CORPORATION JUMPS BACK INTO THE SPOTLIGHT
Replies: 5
Views: 2155

Re: GERON CORPORATION JUMPS BACK INTO THE SPOTLIGHT

Hardly a spotlight.
by Gwikley
Tue Dec 04, 2018 6:35 am
Forum: ImetelChat
Topic: Here are the slides from Dr. Mascarenhas presentation on MF
Replies: 2
Views: 961

Re: Here are the slides from Dr. Mascarenhas presentation on MF

Honest enthusiasm is warranted for both patients and the stock. Impressive.
by Gwikley
Mon Nov 05, 2018 1:55 am
Forum: ImetelChat
Topic: State of the Union, post Storm
Replies: 4
Views: 1435

Re: State of the Union, post Storm

The economics of this company while controversial, are certainly important. That they are not discussed here is polite and respectful of the "science" emphasis of this board.
by Gwikley
Sun Oct 28, 2018 9:05 pm
Forum: ImetelChat
Topic: Data release
Replies: 0
Views: 1041

Data release

Seems we are facing yet ANOTHER binary decision. Is the data good enough to proceed, or did will we find that JnJ bailed because of significantly negative stats? Historically we have not fared all that well when it comes to go/no-go decisions. Just a hope, expressed here, that the coin flips in our ...
by Gwikley
Tue Oct 09, 2018 6:51 pm
Forum: ImetelChat
Topic: Why does Janssen need 12 months to transition the data to Geron & 9 months to start a P3 in MDS?
Replies: 11
Views: 2184

Re: Why does Janssen need 12 months to transition the data to Geron & 9 months to start a P3 in MDS?

You give color to the mindless,endless frustrations around this company. Like you I've no idea of the complexity both technically and legally around the cessation of the CD and transfer of the accumulated data. There is the compassionate consideration as well. Will the current patients be able to re...