Search found 7 matches

by rinconj
Thu Apr 27, 2023 5:53 am
Forum: ImetelChat
Topic: Is this why Dr. Scarlett has been grinning so much
Replies: 11
Views: 2460

Re: Is this why Dr. Scarlett has been grinning so much

A glimmer of hope that that a cocktail with Imetelstat as a key ingredient might be effective again some solid tumors? We know Geron hasn't had any luck with solid tumors they have tried, but we all have heard that 90% of cancers use telomerase to survive. Maybe someone at Geron is still working on ...
by rinconj
Sat Sep 04, 2021 4:53 pm
Forum: ImetelChat
Topic: 2.0?
Replies: 5
Views: 2630

Re: 2.0?

The authors are all affiliated with Oxford university and have nothing to do with Geron? How strong are Geron's patents?
If some other company developed a better telomerase inhibitors than Imetelstat, do they have to pay Geron?
by rinconj
Wed May 26, 2021 6:16 am
Forum: ImetelChat
Topic: How does Imetelstat compare to antibiotics that inhibit telomerase?
Replies: 1
Views: 1032

Re: How does Imetelstat compare to antibiotics that inhibit telomerase?

Excerpted from the following book:” Antibiotics oflaxacin and levofloxacin inhibit the telomerase in cell extracts. Helenalin (a natural sesquiterpene lactone), polyunsaturated fatty acids with cis-double bond, also inhibit the telomerase [ 20 ]. However, some dietary polyphenols have been suggested...
by rinconj
Wed May 26, 2021 6:08 am
Forum: ImetelChat
Topic: How does Imetelstat compare to antibiotics that inhibit telomerase?
Replies: 1
Views: 1032

How does Imetelstat compare to antibiotics that inhibit telomerase?

Just found some articles on using some antibiotics that inhibit telomerase to treat cancers: 1.https://www.nature.com/articles/s41467-021-23068-1 2.https://today.uic.edu/can-antibiotics-treat-human-diseases-in-addition-to-bacterial-infections 3.https://m.ebiotrade.com/newsf/2013-7/201375154328895.ht...
by rinconj
Tue Jul 16, 2019 6:14 pm
Forum: ImetelChat
Topic: Sdraw
Replies: 3
Views: 7490

Re: Sdraw

He only has 3 twits so far this year and the last one was on Apr 10. I wonder how he is doing nowadays.
by rinconj
Tue Apr 23, 2019 4:14 am
Forum: ImetelChat
Topic: A very basic note on other telomerase inhibitors
Replies: 4
Views: 3120

Re: A very basic note on other telomerase inhibitors

I appreciate your effort to identify all potential competitors. We all need to do our DD. It's interesting to know that during Dr. Sekeres and Dr. Steensma's recent online conference call about future treatments of MDS they never mentioned Argenx or its AML and MDS drug cusatuzumab (ARGX-110). Cusat...
by rinconj
Wed Oct 10, 2018 7:32 am
Forum: ImetelChat
Topic: What do we know for sure at this point? And what can we speculate?
Replies: 7
Views: 5830

Re: What do we know for sure at this point? And what can we speculate?

That MF article about the failures in breast cancer and other solid tumors seems to be one of the many conflicting results I've read about Imet. It's true that Geron stopped their breast cancer trials due to lack of efficacy in 2012, but why are we seeing positive results from other more recent pape...