Search found 348 matches

by Ryan
Tue Mar 19, 2024 2:50 pm
Forum: ImetelChat
Topic: TD Cowen, Stifel, and Barclays
Replies: 1
Views: 718

TD Cowen, Stifel, and Barclays

I’m seeing new underwriters in TD Cowen and Barclays. RA Capital headlines, assume they took 9.99% of offering to stay at 9.99%. Did not see a mention of NEA though. These investment firms are willing to pay $3 when they could have literally paid $1’s last week in the open market. Things have certai...
by Ryan
Tue Mar 19, 2024 2:58 am
Forum: ImetelChat
Topic: This is a big deal- a convert
Replies: 2
Views: 847

Re: This is a big deal- a convert

Yawn. I respectfully disagree. He is a journalist with no background in science, and has been nothing but biased, glib, and unimpressive with his tales on Geron. His “article” (blog) is nothing but more gaseous click bait. He is now getting people to read who had never heard of Geron, and people to ...
by Ryan
Sat Mar 16, 2024 6:30 pm
Forum: ImetelChat
Topic: Public Hearing Comments (Patient #3; Patient #9)
Replies: 4
Views: 813

Re: Public Hearing Comments (Patient #3; Patient #9)

For those of you who didn't watch/listen to the ADCOM meeting, I recommend you listen to the public comments from Patient #3. Her story begins at the 4:32:07 mark of the video. https://www.youtube.com/watch?v=Om-cKKBsMS4 Many of us have "hung-in-there" for quite a while.....hoping the drug (and com...
by Ryan
Fri Mar 15, 2024 6:02 am
Forum: ImetelChat
Topic: Quite Surprising that....
Replies: 10
Views: 2698

Re: Quite Surprising that....

He did state his rationale - that the risks ultimately outweighed the benefit. He bought into the FDA shaping of the cytopenias, despite multiple clinicians (and he would also know) that these are manageable in MDS centers. I think a real interesting moment was when the Dr from the Moffitt Center in...
by Ryan
Fri Mar 15, 2024 3:53 am
Forum: ImetelChat
Topic: Geron Announces FDA Oncologic Drugs Advisory Committee Votes in Favor of the Clinical Benefit/Risk Profile of Imetelstat
Replies: 0
Views: 728

Geron Announces FDA Oncologic Drugs Advisory Committee Votes in Favor of the Clinical Benefit/Risk Profile of Imetelstat

Geron PR, AKA victory lap, today not posted here yet I don’t think: https://ir.geron.com/investors/press-releases/press-release-details/2024/Geron-Announces-FDA-Oncologic-Drugs-Advisory-Committee-Votes-in-Favor-of-the-Clinical-BenefitRisk-Profile-of-Imetelstat-for-the-Treatment-of-Transfusion-Depend...
by Ryan
Thu Mar 14, 2024 8:47 pm
Forum: ImetelChat
Topic: March 14th
Replies: 27
Views: 5438

Re: March 14th

Very entertaining... worst fear than any horror movie I have seen. Would have been perfect... except this is real life, impacting real patients and real families. I am ashamed at the incompetent FDA members and the panelist who voted no. May their family and friends never get this disease. Ash a bi...
by Ryan
Thu Mar 14, 2024 7:10 pm
Forum: ImetelChat
Topic: March 14th
Replies: 27
Views: 5438

Re: March 14th

Speakers 8 and 9 were patients. They were extremely compelling and 100% advocating for Imet. Dare I say, tear-jerkers...

9 Speakers was 9-0 in favor of Imetelstat.
by Ryan
Thu Mar 14, 2024 6:38 pm
Forum: ImetelChat
Topic: March 14th
Replies: 27
Views: 5438

Re: March 14th

Speaker #3 was a patient from TX, who said she was ready to meet the Lord upon hearing her treatments were not working. Before Imetelstat... needless to say, amazing story. Speaker #4 is Dr / expert from Cornell, non-sponsored who had consulted with Geron in the past.... "Enthusiastic to have Imetel...
by Ryan
Thu Mar 14, 2024 6:28 pm
Forum: ImetelChat
Topic: March 14th
Replies: 27
Views: 5438

Re: March 14th

Speaker #2 is equally "enthusiastic" (her word). She is a non-sponsor patient advocate with the MDS Foundation.

Seems the tide has definitely taking a decidedly (and maybe expected) +++ positive turn as the talk turns from anecdotes and real stories as compared to the data jargon...
by Ryan
Thu Mar 14, 2024 6:24 pm
Forum: ImetelChat
Topic: March 14th
Replies: 27
Views: 5438

Re: March 14th

Speaker #1 in the Open Hearing: MDS Doctor / expert in Canada. Had 3 patients in study and described experience of one, who was unblinded... She used the phrase "incredible drug", and "impressed". Halelujah moment for sure! Not that we did not know of these efficacy effects, however we did need this...
by Ryan
Thu Mar 14, 2024 5:28 pm
Forum: ImetelChat
Topic: March 14th
Replies: 27
Views: 5438

Re: March 14th

The Geron team and collaborators are indeed doing a great job. It’s hard not to characterize the FDA teams posture as being prosecuting attorneys. Ultimately this is nerve wracking as they are of course the ultimate arbiter as to if the drug is approved and the labeling. So I stick with my call that...
by Ryan
Wed Mar 13, 2024 9:32 pm
Forum: ImetelChat
Topic: Basic Considerations....
Replies: 13
Views: 2529

Re: Basic Considerations....

Numerous great / insightful comments the past 36 hours. I would say nothing left to do but wait. I still believe the vote will be unanimous in favor. It’s b/c of these Basic Considerations, because of (the unchanged) p values, and because of Geron’s response along with the independent experts from V...
by Ryan
Tue Mar 12, 2024 1:38 am
Forum: ImetelChat
Topic: New Comment on Regulatory docket
Replies: 2
Views: 626

Re: New Comment on Regulatory docket

Nice. I missed it in the noise - I see the link was posted but just now have read the comment (that I copy pasted).

This is truly an amazing comment. Onward.
by Ryan
Tue Mar 12, 2024 1:16 am
Forum: ImetelChat
Topic: New Comment on Regulatory docket
Replies: 2
Views: 626

New Comment on Regulatory docket

New comment posted. Ignore the noise, only truthful testimonials like this are important now. we are close to finally, finally proving, and being validated as, a life saving drug: Comment My name is Sharon Sams Chandler and I am a 59 year old woman who lives in Roanoke, TX. I am writing this to expl...
by Ryan
Mon Mar 11, 2024 7:54 pm
Forum: ImetelChat
Topic: Finally, disease modification?
Replies: 4
Views: 851

Re: Finally, disease modification?

24 million+ (edited from 30 Million, I overestimated) shares traded here say it’s a spring, or a slinkie :mrgreen:

I guess it's safe to say around 100 million shares will trade Friday. Onward here we go...
by Ryan
Mon Mar 11, 2024 7:06 pm
Forum: ImetelChat
Topic: Finally, disease modification?
Replies: 4
Views: 851

Re: Finally, disease modification?

Did you pay for access? It possible this is articulated , but of course the Headline ends in a question mark.

Isn’t that appropriate for Geron…? Always a question mark lurks… and of course max pain for retail investors as the question mark is just never removed.

I digress, Thursday it is.
by Ryan
Sat Mar 09, 2024 6:43 pm
Forum: ImetelChat
Topic: Taking the temperature at the FDA
Replies: 5
Views: 1136

Re: Taking the temperature at the FDA

A stock will not be halted based on an event, only a market reaction to an event, which causes a trade imbalance… So the stock will not be halted just based on the meeting happening, only if the stock trading gets nuts. I would suspect a 20-30 million trade day, and would doubt that stock is halted....
by Ryan
Sat Mar 09, 2024 12:41 am
Forum: ImetelChat
Topic: PPS
Replies: 79
Views: 133414

Re: PPS

Hopefully this is the start of something new, and up, for the PPS today, and not another, yet another, head fake. I mean the meeting is next week. :arrow:
by Ryan
Thu Mar 07, 2024 4:20 pm
Forum: ImetelChat
Topic: Additional comments to FDA
Replies: 10
Views: 2621

Re: Additional comments to FDA

Calm before the storm, it seems. I welcome it.
Seems I have one hand and a peace sign left to count down. Should be a good day.
by Ryan
Mon Mar 04, 2024 4:46 pm
Forum: ImetelChat
Topic: Using fingers to count down now
Replies: 3
Views: 1341

Using fingers to count down now

That ODAC meeting is getting close.

Per conversations and pure conjecture on other boards, I would say that the vote will be unanimous, in favor of course.