ImetelChat

I cringe to think what the FDA would have done absent the ODAC and the 12-2 vote. I originally thought the ODAC was basically just another FDA hurdle they would misuse to create additional issues for Geron/Imetelstat on their path to commercialization. While I was likely right regarding the FDA’s in...

At the Needham fireside chat I think Dr. John Scarlett was more upbeat than I have ever seen him. He made several comments that reflected his enthusiasm and confidence that both patients and investors would be rewarded for their patience. Of course, he also reiterated many of the key points from pas...

Thanks, biopearl123 for your excellent thoughts on the possible impacts on the FDA because of the ODAC meeting. You are on point for sure that it is an evolutionary process and people’s minds are changed with education. I am hopeful the FDA will approve MDS ahead of the PDUFA date of June 16 as they...

Many of you may have known that RYTELO is the proposed trade name for Imetelstat. Anyway it was included in the FDA’s briefing document for the ODAC. “ Executive Summary Purpose/Objective of the AC Meeting The Applicant is seeking approval of imetelstat (proposed trade name RYTELO) for the treatment...

Definitely agree with Bigfun and second on the thanks to rccola335 for the links. It's always good to get Dr. John Scarlett's thoughts on where things stand and how hew he perceives the future, especially the next few months. Secondly, I would hope minimally board members could check out the second ...

Thanks biopearl123 for all your time, efforts and attention to detail. You have again laid out several really important points/observations from the ODAC meeting on 3/14. As usual, you have taken the high road and we all admire your character and discipline in that regard. I for one, prefer to take ...

I have watched Geron and its stock and have been an investor for a very long time. Certainly not the longest here, maybe even just average. I know there are many old timer investors here that are determined to see this through, many of us well over a decade and some even decades. Most of us know of ...

Yes, I agree. Unfortunately I don't drink anything stronger than coffee. But if I did, it would be Wild Turkey Liquor.

Agreed! I have always believed that Dr. Faye Feller was made for the CMO job, especially after watching the interview video link posted here long ago. She has also obviously grown into the job from her original strong underpinnings to be able to give the stellar performance we saw today. I know a lo...

Vote was 12-2 as follows: 1. AC-Joan Powell YES 2. AC-Ravi Madan(Chair) NO 3. AC-Neil Vasan YES 4. AC-Jorge Nieva YES 5. AC-Daniel Spratt YES 6. AC_Christopher Lieu YES 7. AC-Ashley Rosko YES 8. AC-Mark Conaway NO 9. AC-Anthony Hunter YES 10. AC-David Mitchell YES 11. AC-Toni Choueiri YES 12. AC-Pam...

Maybe my glasses are just to rose colored but while the FDA may have a right and need to play the devil’s advocate role, there is no justification for misconstruing the facts on AE’s or misusing statistics to water down the various strengths and stellar results of the CTs whose design they signed of...

Based on our experience, I would never under estimate the number of monkey wrenches the FDA is so blatantly willing to use to delay approval or continue to maintain its all out assault on any CT using Imetelstat. However, were we ever specifically/exactly certain what all the FDA was looking for out...

Members probably know this but the EAP is not available in India or anywhere outside of USA. Per the Geron website: The imetelstat expanded access protocol (EAP) is a U.S.-only protocol for eligible adult participants diagnosed with lower risk (very low, low, intermediate risk by IPSS-R) myelodyspla...

Back in my management days, we estimated an employee’s benefits cost 30-35% of their salaries (e.g. medical, 401k/retirement, etc.)

This article was interesting to me from several perspectives. It’s not a long read and has several striking quotes. And comparing the dance around CAR-T therapy’s issues compared to Dr. Patnaik’s comments in Lance is just another example to me of the subversive cabal working against Imetelstat comme...

Yes, great summary biopearl123. And to pile on kmall’s post, there is clearly something not right about the aim of Dr. Patnaik’s comments. I would suggest ulterior motives or just inept, could be both. I don’t think I’m paranoid here but I just find it hard to trust anyone or entity that continues a...

Dr. Aggarwal has been on our radar since the VIVO Capital buy-in. http://imetelchat.imetelstat.eu/imetelchat.imetelstat.eu/viewtopic.php?f=1&t=1247&p=4004&hilit=Vivo+Capital#p4004 Not sure why he is no longer employed there, I guess it does allow JS to make this comment in the announcement: "Dr. Agg...

mistergern, yes many of us here have been steadfast with our GERN stock positions. Maybe wrongly so however, I think instead of bashing Dr Scarlett and company, let’s not lose sight of the responsible parties for the most grievous offenses of incessant delays, ignoring great and unique results, road...